Emerging drugs for acute myocardial infarction

scientific article published on March 2010

Emerging drugs for acute myocardial infarction is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/14728210903405619
P698PubMed publication ID20055689

P2093author name stringRosanna Abbate
Serafina Valente
Chiara Lazzeri
Roberto Tarquini
G F Gensini
P2860cites workTime from symptom onset to treatment and outcomes after thrombolytic therapy. GUSTO-1 Investigators.Q53367479
The Hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction.Q53727713
Abciximab as Adjunctive Therapy to Reperfusion in Acute ST-Segment Elevation Myocardial InfarctionQ56944163
Comparison of benefits and complications of hirudin versus heparin for patients with acute coronary syndromes undergoing early percutaneous coronary interventionQ56944673
ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention—Summary ArticleQ56986819
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death--executive summary: A report of the American College of Cardiology/American Heart Association Task Force and the European SQ58973291
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology:Q22242896
Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarctionQ24683044
Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trialQ28193186
Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirinQ28200091
Clinical aspects of platelet inhibitors and thrombus formationQ28210313
Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) TrialQ28211092
A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery diseaseQ28213238
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevationQ28218789
Bivalirudin in patients undergoing primary angioplasty for acute myocardial infarction (HORIZONS-AMI): 1-year results of a randomised controlled trialQ28256871
Bivalirudin during primary PCI in acute myocardial infarctionQ28281179
Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized TrialQ28300233
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolaseQ28373346
Ticagrelor versus clopidogrel in patients with acute coronary syndromesQ29619002
Primary PCI for myocardial infarction with ST-segment elevationQ30442496
A randomized double-blind trial of intravenous trimetazidine as adjunctive therapy to primary angioplasty for acute myocardial infarction.Q31966140
Refractory no-reflow successfully treated with local infusion of high-dose adenosine and verapamil--a case reportQ32066885
Recognition, treatment, and prevention of heparin-induced thrombocytopenia: review and updateQ33368280
Clinical practice. Heparin-induced thrombocytopeniaQ33372371
Stem cells improve left ventricular function in acute myocardial infarction.Q33428042
Hotlines and clinical trial updates presented at the European Society of Cardiology Meeting 2009: data from RE-LY, PLATO, MADIT-CRT, PROTECT, SYNTAX, TRITON and moreQ33506115
Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overviewQ33860081
Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock.Q33872047
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) studyQ34009506
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interactionQ34168972
Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic TherapyQ34350556
Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hourQ34398044
A population-based study of the drug interaction between proton pump inhibitors and clopidogrelQ34603772
ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the MQ34649834
Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization andQ34775547
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of CardiologyQ34830023
Genetic determinants of response to clopidogrel and cardiovascular eventsQ34910210
Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndromeQ34956075
Cardiogenic shock complicating acute myocardial infarction: expanding the paradigmQ35160529
Society of cardiac angiography and interventions: Suggested management of the no‐reflow phenomenon in the cardiac catheterization laboratoryQ35546872
2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New EvideQ37031817
The pathogenesis and treatment of no-reflow occurring during percutaneous coronary interventionQ37060929
Late sodium current inhibition as a new cardioprotective approachQ37156945
Hyperglycaemia in acute coronary syndromes: risk-marker or therapeutic target?Q37242193
A systematic review and meta-analysis of intra-aortic balloon pump therapy in ST-elevation myocardial infarction: should we change the guidelines?Q37377110
Orphan targets for reperfusion injury.Q37436743
Aggressive chronic platelet inhibition with prasugrel and increased cancer risks: revising oral antiplatelet regimens?Q37509176
Management of cardiogenic shock: focus on tissue perfusionQ37547340
Adjunctive low molecular weight heparin during fibrinolytic therapy in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials.Q37554115
P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use.Q37562606
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trialsQ37590925
Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION studyQ38501716
Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction: a quantitative reviewQ38554587
Indications for implantable cardioverter-defibrillators based on evidence and judgmentQ39953794
Usefulness of intra-aortic balloon pump counterpulsation in patients with cardiogenic shock from acute myocardial infarctionQ39962044
Glucose normalization and outcomes in patients with acute myocardial infarctionQ39996366
Results of the first clinical study of adjunctive CAldaret (MCC-135) in patients undergoing primary percutaneous coronary intervention for ST-Elevation Myocardial Infarction: the randomized multicentre CASTEMI studyQ40280772
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist propertiesQ41906079
???Q28222150
Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusionQ41967273
The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatinQ42049501
Intracoronary versus intravenous abciximab in ST-segment elevation myocardial infarction: rationale and design of the CICERO trial in patients undergoing primary percutaneous coronary intervention with thrombus aspirationQ42590257
Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trialQ42614551
Ticagrelor--is there need for a new player in the antiplatelet-therapy field?Q43283545
Otamixaban for the treatment of patients with non-ST-elevation acute coronary syndromes (SEPIA-ACS1 TIMI 42): a randomised, double-blind, active-controlled, phase 2 trialQ43283673
Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomesQ43445863
Use of the percutaneous left ventricular assist device in patients with severe refractory cardiogenic shock as a bridge to long-term left ventricular assist device implantation.Q43509133
P2y(12), a new platelet ADP receptor, target of clopidogrelQ43591480
Low-dose glucose-insulin-potassium is ineffective in acute myocardial infarction: results of a randomized multicenter Pol-GIK trialQ43625417
The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trialQ43796510
Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLandQ43811969
Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial.Q44074134
Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarctionQ44128296
No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary interventionQ44270415
Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis modelQ44316947
Cardioprotective effect of trimetazidine during thrombolytic therapy in patients with acute myocardial infarction.Q44379335
Glucose-insulin-potassium infusion inpatients treated with primary angioplasty for acute myocardial infarction: the glucose-insulin-potassium study: a randomized trialQ44574635
Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidityQ44642265
A randomized evaluation of the effects of glucose-insulin-potassium infusion on myocardial salvage in patients with acute myocardial infarction treated with reperfusion therapyQ44950894
Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trialQ45238837
Efficacy of ranolazine in patients with chronic angina observations from the randomized, double-blind, placebo-controlled MERLIN-TIMI (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Segment Elevation Acute Coronary Syndromes) 36 TrQ46038950
Platelet inhibition with prasugrel and increased cancer risks: potential causes and implicationsQ46046440
Ischemia detected on continuous electrocardiography after acute coronary syndrome: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis In Myocardial InQ46048410
Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trialQ46105774
Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-upQ46178120
Time of onset and outcome of cardiogenic shock in acute coronary syndromesQ46252624
Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patientsQ46338658
Initial assessment of clinical impact of a drug interaction between clopidogrel and proton pump inhibitorsQ46373411
Short-term bridge to heart transplant using the BVS 5000 external ventricular assist device.Q46432954
Levosimendan is superior to enoximone in refractory cardiogenic shock complicating acute myocardial infarctionQ46457030
A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).Q46528602
Metabolic management of acute myocardial infarction comes to the fore and extends beyond control of hyperglycemiaQ46621659
Impact of reversibility of no reflow phenomenon on 30-day mortality following percutaneous revascularization for acute myocardial infarction-insights from a 1,328 patient registryQ46662897
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in MyocQ46868498
Prasugrel versus clopidogrel in patients with acute coronary syndromesQ46915044
Cardiac mitochondrial alterations induced by insulin deficiency and hyperinsulinaemia in rats: targeting membrane homeostasis with trimetazidineQ46918342
Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trialsQ46928598
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidineQ46960760
Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shockQ46983271
Fondaparinux in ST-segment elevation myocardial infarction: the drug, the strategy, the environment, or all of the above?Q46990598
Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism.Q48887708
The disposition of prasugrel, a novel thienopyridine, in humans.Q50700156
Randomized comparison of intra-aortic balloon support with a percutaneous left ventricular assist device in patients with revascularized acute myocardial infarction complicated by cardiogenic shock.Q51535796
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmyocardial infarctionQ12152
P304page(s)87-105
P577publication date2010-03-01
P1433published inExpert Opinion on Emerging DrugsQ5421207
P1476titleEmerging drugs for acute myocardial infarction
P478volume15

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