Met interacts with EGFR and Ron in canine osteosarcoma

scientific article published on 08 December 2011

Met interacts with EGFR and Ron in canine osteosarcoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1476-5829.2011.00309.X
P932PMC publication ID3969615
P698PubMed publication ID22235915

P2093author name stringC Khanna
C A London
C Mazcko
J K McCleese
M D Bear
S K Kulp
P2860cites workCross-talk between the proto-oncogenes Met and RonQ22254408
EGFR/Met association regulates EGFR TKI resistance in breast cancerQ24338635
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibQ24646295
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signalingQ27851406
The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasivenessQ28201215
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor familyQ28285975
Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor functionQ28678683
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitorsQ29547463
Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cellsQ30415408
Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factorQ30436756
Gefitinib: a review of its use in the management of advanced non-small-cell lung cancerQ33207883
Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.Q33916081
The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapyQ34325749
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.Q34398347
From concept to reality: the long road to c-Met and RON receptor tyrosine kinase inhibitors for the treatment of cancerQ34939284
HGF-independent potentiation of EGFR action by c-MetQ35078530
Update on the biology and management of canine osteosarcomaQ35173803
Mitogen-activated protein kinases in apoptosis regulationQ35743118
Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cellsQ36090650
RON, a tyrosine kinase receptor involved in tumor progression and metastasisQ36096934
Small molecules with EGFR-TK inhibitor activityQ36108991
Signaling networks assembled by oncogenic EGFR and c-MetQ36392991
Cross talk between c-Met and epidermal growth factor receptor during retinal pigment epithelial wound healingQ36407762
Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumorsQ36486421
Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patientsQ36523502
Constitutive activation of the RON gene promotes invasive growth but not transformationQ36564393
Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladderQ36615866
Comparative biology of human and canine osteosarcoma.Q36757513
Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.Q36882696
Crosstalk in Met receptor oncogenesisQ37598460
Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicinQ39620039
met oncogene activation qualifies spontaneous canine osteosarcoma as a suitable pre-clinical model of human osteosarcoma.Q39859049
Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cellsQ40006240
Epidermal growth factor receptor in osteosarcoma: expression and mutational analysisQ40131620
A novel small molecule Met inhibitor, PF2362376, exhibits biological activity against osteosarcoma.Q40179159
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.Q40443024
Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cellsQ40893206
The HGF receptor family: unconventional signal transducers for invasive cell growthQ41458148
Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancerQ41969702
Acquired resistance of non-small cell lung cancer cells to MET kinase inhibition is mediated by a switch to epidermal growth factor receptor dependencyQ42081770
Interaction between heterologous receptor tyrosine kinases. Hormone-stimulated insulin receptors activate unoccupied IGF-I receptors.Q42825078
Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomasQ42854019
The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cellsQ43680631
A randomized controlled trial of octreotide pamoate long-acting release and carboplatin versus carboplatin alone in dogs with naturally occurring osteosarcoma: evaluation of insulin-like growth factor suppression and chemotherapy.Q44061944
Switching signals on or off by receptor dimerizationQ46100759
The prognostic significance of RON and MET receptor coexpression in patients with colorectal cancerQ46553705
Expression of hepatocyte growth factor and the proto-oncogenic receptor c-Met in canine osteosarcomaQ47834432
The expression of epidermal growth factor receptor and its downstream signaling molecules in osteosarcoma.Q51825091
Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylationQ67689119
Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell linesQ73491986
Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cellsQ74172362
STEALTH liposome-encapsulated cisplatin (SPI-77) versus carboplatin as adjuvant therapy for spontaneously arising osteosarcoma (OSA) in the dog: a randomized multicenter clinical trialQ74599244
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomasQ77386062
Epidermal growth factor receptor expression in high-grade osteosarcomas is associated with a good clinical outcomeQ80341321
Tyrosine kinases as targets for cancer therapyQ80367757
P4510describes a project that usesImageJQ1659584
P433issue2
P304page(s)124-139
P577publication date2011-12-08
P1433published inVeterinary and Comparative OncologyQ15759976
P1476titleMet interacts with EGFR and Ron in canine osteosarcoma
P478volume11

Reverse relations

cites work (P2860)
Q95840408AKT and JUN are differentially activated in mesenchymal stem cells after infection with human and canine oncolytic adenoviruses
Q92190792Aberrant RON and MET Co-overexpression as Novel Prognostic Biomarkers of Shortened Patient Survival and Therapeutic Targets of Tyrosine Kinase Inhibitors in Pancreatic Cancer
Q38220804Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology
Q49602648Canine sarcomas as a surrogate for the human disease.
Q34768509Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts
Q28607304Comparative oncology: what dogs and other species can teach us about humans with cancer
Q42634367Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.
Q41901776Dasatinib Modulates Invasive and Migratory Properties of Canine Osteosarcoma and has Therapeutic Potential in Affected Dogs
Q36034972Effects of epidermal growth factor receptor kinase inhibition on radiation response in canine osteosarcoma cells
Q28084034Epidermal growth factor signaling in transformed cells
Q28593437Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis
Q42837140Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer
Q27313336OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts
Q92565594Ursolic acid suppresses the biological function of osteosarcoma cells
Q89170829miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells

Search more.