| scholarly article | Q13442814 |
| P50 | author | Domenico Maiorano | Q42732029 |
| Siem Van Der Laan | Q43185178 | ||
| P2093 | author name string | Philippe Coulombe | |
| Chames Kermi | |||
| Dana Hodroj | |||
| Nikolay Tsanov | |||
| P2860 | cites work | Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin | Q24293055 |
| Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin | Q24298173 | ||
| CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis | Q24298314 | ||
| A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1 | Q24301361 | ||
| Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells | Q24302543 | ||
| Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis. | Q24304921 | ||
| DNA-damage response control of E2F7 and E2F8 | Q24306816 | ||
| FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress | Q24309138 | ||
| Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase | Q24309424 | ||
| FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress | Q24312780 | ||
| PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex | Q24312855 | ||
| Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination | Q24563236 | ||
| Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint | Q24563819 | ||
| N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome | Q24563960 | ||
| The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells | Q24599645 | ||
| SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation | Q24653723 | ||
| DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1 | Q24672982 | ||
| Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen | Q27653714 | ||
| Analysis of the role of PCNA-DNA contacts during clamp loading | Q27659293 | ||
| Structure and mechanism of human DNA polymerase η | Q27662730 | ||
| The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. | Q53328853 | ||
| p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition | Q79077543 | ||
| Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts | Q81313201 | ||
| PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication | Q81640024 | ||
| Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis | Q82812575 | ||
| p53 and p21 regulate error-prone DNA repair to yield a lower mutation load | Q83294924 | ||
| Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA | Q27730804 | ||
| Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA | Q27733704 | ||
| XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis | Q28141884 | ||
| The Cdt1 protein is required to license DNA for replication in fission yeast | Q28141890 | ||
| Essential role of human CDT1 in DNA replication and chromatin licensing | Q28207460 | ||
| Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint | Q28212584 | ||
| The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase | Q28216141 | ||
| Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair | Q28240258 | ||
| CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation | Q28290857 | ||
| PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination | Q28291192 | ||
| PCNA, the maestro of the replication fork | Q28303101 | ||
| Oncogenic potential of the DNA replication licensing protein CDT1 | Q28507582 | ||
| Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage | Q28646728 | ||
| Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
| Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis | Q29619757 | ||
| Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage | Q30410142 | ||
| CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation | Q30430339 | ||
| Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. | Q31136186 | ||
| DNA damage induced Pol eta recruitment takes place independently of the cell cycle phase | Q33508790 | ||
| Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage | Q33733896 | ||
| PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule? | Q34042861 | ||
| The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells. | Q34144213 | ||
| Localisation of human DNA polymerase kappa to replication foci | Q34157610 | ||
| CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase | Q34215301 | ||
| Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression | Q34221836 | ||
| Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs | Q34222698 | ||
| Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage | Q34353149 | ||
| A p53-dependent checkpoint pathway prevents rereplication | Q34533175 | ||
| A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus | Q35222221 | ||
| Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase | Q35237385 | ||
| DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity | Q35633543 | ||
| Translesion synthesis in mammalian cells | Q36541050 | ||
| Translesion synthesis: Y-family polymerases and the polymerase switch | Q36760898 | ||
| Y-family DNA polymerases and their role in tolerance of cellular DNA damage. | Q36778894 | ||
| The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing | Q36898085 | ||
| UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability | Q37080401 | ||
| Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans | Q37105901 | ||
| Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells | Q38304800 | ||
| A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. | Q38666669 | ||
| Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro | Q38782589 | ||
| The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells | Q39487655 | ||
| Regulation of translesion synthesis DNA polymerase eta by monoubiquitination | Q39738889 | ||
| ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells | Q39745219 | ||
| p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. | Q39941387 | ||
| The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair | Q40273191 | ||
| Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines | Q40529050 | ||
| Ubiquitin-dependent DNA damage bypass is separable from genome replication | Q41170108 | ||
| Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2 | Q41928650 | ||
| Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1. | Q42152367 | ||
| Two different replication factor C proteins, Ctf18 and RFC1, separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV irradiation. | Q42196591 | ||
| Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation | Q42859238 | ||
| Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. | Q44785638 | ||
| CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing | Q47069271 | ||
| Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis | Q47858261 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3692-3706 | |
| P577 | publication date | 2014-01-14 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage | |
| P478 | volume | 42 |
| Q28253511 | A novel cell permeable DNA replication and repair marker |
| Q48109551 | An ATR-dependent function for the Ddx19 RNA helicase in nuclear R-loop metabolism. |
| Q90365195 | Bistable switches as integrators and actuators during cell cycle progression |
| Q37432824 | Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells. |
| Q60924153 | Direct binding of Cdt2 to PCNA is important for targeting the CRL4 E3 ligase activity to Cdt1 |
| Q35497978 | Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21(WAF1), Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells |
| Q34480026 | Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry |
| Q58768271 | Maneuvers on PCNA Rings during DNA Replication and Repair |
| Q36302154 | Mismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase |
| Q36209538 | PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress |
| Q47104269 | Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
| Q35833998 | Protein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stability |
| Q37396238 | Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. |
| Q38534219 | Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance. |
| Q92947920 | Regulation of translesion DNA synthesis in mammalian cells |
| Q26827585 | Role of DNA polymerase κ in the maintenance of genomic stability |
| Q64387319 | Role of Y-family translesion DNA polymerases in replication stress: Implications for new cancer therapeutic targets |
| Q92328617 | The PCNA interaction motifs revisited: thinking outside the PIP-box |
| Q35205026 | The fork and the kinase: a DNA replication tale from a CHK1 perspective |
| Q38498838 | The identification of translesion DNA synthesis regulators: Inhibitors in the spotlight. |
| Q34044719 | Thymine DNA glycosylase is a CRL4Cdt2 substrate |
| Q39079498 | Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases. |
| Q28771759 | USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication |
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