| P7228 | access restriction status | open access | Q232932 |
| P50 | author | Jae Youl Cho | Q67190604 |
| | Bong-Sik Yun | Q87601546 |
| | Man Hee Rhee | Q40239551 |
| | Mehari Endale | Q49044835 |
| P2093 | author name string | Tae-Hwan Kim | |
| | Seung-Hyung Kim | |
| | Yi-Seong Kwak | |
| | Na-Mi Kim | |
| P2860 | cites work | TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells. | Q51979780 |
| | The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. | Q54595193 |
| | Torilin, a Sesquiterpene fromTorilis japonica, Reverses Multidrug-Resistance in Cancer Cells | Q56686484 |
| | Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes. | Q64991174 |
| | Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta | Q74047657 |
| | Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures | Q74179811 |
| | Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaB | Q80987392 |
| | Anti-angiogenic activity of torilin, a sesquiterpene compound isolated fromTorilis japonica | Q104666991 |
| | Natural Products Triggering Biological Targets- A Review of the Anti-Inflammatory Phytochemicals Targeting the Arachidonic Acid Pathway in Allergy Asthma and Rheumatoid Arthritis | Q37800950 |
| | Cell type-specific function of TAK1 in innate immune signaling | Q38105722 |
| | Anti-angiogenic activity of torilin, a sesquiterpene compound isolated from Torilis japonica | Q38526276 |
| | Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells | Q39144033 |
| | Ischemia induces regulator of G protein signaling 2 (RGS2) protein upregulation and enhances apoptosis in astrocytes | Q39759467 |
| | Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages | Q40895343 |
| | The role of p38 mitogen-activated protein kinase in IL-1 beta transcription | Q40956628 |
| | Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages | Q41100700 |
| | Suppression by a sesquiterpene lactone from Carpesium divaricatum of inducible nitric oxide synthase by inhibiting nuclear factor-kappaB activation | Q43557351 |
| | Anti-protozoal efficacy of high performance liquid chromatography fractions of Torilis japonica and Sophora flavescens extracts on Neospora caninum and Toxoplasma gondii. | Q45105652 |
| | Torilin ameliorates type II collagen-induced arthritis in mouse model of rheumatoid arthritis | Q45228751 |
| | New Guaiane Sesquiterpenes from the Fruits of Torilis japonica | Q46338310 |
| | Antimicrobial activity of torilin isolated from Torilis japonica fruit against Bacillus subtilis | Q46734764 |
| | Essential function for the kinase TAK1 in innate and adaptive immune responses | Q50335551 |
| | A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB | Q24321775 |
| | Toll-like receptor signalling | Q24570126 |
| | NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses | Q27861101 |
| | The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling | Q28139111 |
| | Phylogenetic perspectives in innate immunity | Q28144345 |
| | Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaB | Q28366566 |
| | TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo | Q28504462 |
| | The two NF-kappaB activation pathways and their role in innate and adaptive immunity | Q29614355 |
| | Ubiquitin signalling in the NF-kappaB pathway | Q29616322 |
| | Anti-invasive activity of torilin, a sesquiterpene compound isolated from Torilis japonica | Q31964847 |
| | Natural products as targeted modulators of the nuclear factor-kappaB pathway | Q34127458 |
| | LPS induction of gene expression in human monocytes | Q34189313 |
| | The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. | Q34505685 |
| | Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones | Q34516946 |
| | The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase | Q34517140 |
| | Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function. | Q35750832 |
| | Nuclear factor-kappaB: its role in health and disease | Q35791198 |
| | Structure and function of Toll receptors and their ligands | Q36760336 |
| | Back to basics: how natural products can provide the basis for new therapeutics | Q36985862 |
| | Signaling to NF-kappaB by Toll-like receptors | Q37009320 |
| | Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potential | Q37178982 |
| | A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation | Q37187515 |
| | Inhibition of inducible NO synthase, cyclooxygenase-2 and interleukin-1beta by torilin is mediated by mitogen-activated protein kinases in microglial BV2 cells | Q37230736 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | Apiaceae | Q145794 |
| | Torilis japonica | Q1468770 |
| | NF-κB | Q411114 |
| | [(4S,6R,7S)-7-(2-acetyloxypropan-2-yl)-1,4-dimethyl-2-oxo-3,3a,4,5,6,7,8,8a-octahydro-1H-azulen-6-yl] (Z)-2-methylbut-2-enoate | Q104667357 |
| | torilin | Q27287943 |
| P6954 | online access status | open access | Q232932 |
| P304 | page(s) | 7250968 | |
| P577 | publication date | 2017-02-20 | |
| P1433 | published in | Mediators of Inflammation | Q2144494 |
| P1476 | title | Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF-κB Activation | |
| P478 | volume | 2017 | |