Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats

scientific article published on 05 February 2014

Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/IJMM.2014.1644
P932PMC publication ID3976124
P698PubMed publication ID24503957
P5875ResearchGate publication ID260120483

P2093author name stringJianping Li
Jianlin Zhou
Hao Peng
Sen Chen
Hongsong Fang
P2860cites workErythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injuryQ24530090
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Caspases: enemies withinQ29547315
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Osteonecrosis of the femoral head: An update in year 2012.Q30426768
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Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged miceQ33806970
New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model.Q34027668
Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord traumaQ34035654
Glucocorticoid-induced osteonecrosisQ34240713
Erythropoietin protects against diabetes through direct effects on pancreatic beta cellsQ34420833
Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) show microstructural bone loss during hibernation but preserve bone macrostructural geometry and strengthQ34712300
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodelingQ34960679
Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosisQ35617021
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.Q35813751
Glucocorticoid-induced osteoporosis and osteonecrosisQ36157622
Glucocorticoids in osteonecrosis of the femoral head: a new understanding of the mechanisms of action.Q37476212
Erythropoetin as a novel agent with pleiotropic effects against acute lung injuryQ37808657
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VEGF and bone cell signalling: an essential vessel for communication?Q38057998
Erythropoietin protects the kidneys against ischemia reperfusion injury by activating hypoxia inducible factor-1alphaQ40129215
Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisoloneQ40317542
Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strengthQ40604863
Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivoQ40962410
Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat.Q41398632
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formationQ41672985
Differential expression of vascular endothelial growth factor in glucocorticoid-related osteonecrosis of the femoral headQ41788376
Protective effect of erythropoietin on myocardial infarction in rats by inhibition of caspase-12 expressionQ41902286
Derivatives of erythropoietin that are tissue protective but not erythropoieticQ47213815
Prevention of glucocorticoid-induced apoptosis in osteocytes and osteoblasts by calbindin-D28kQ47893367
Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury.Q54497604
Glucocorticoid induces apoptosis of osteoblast cells through the activation of glycogen synthase kinase 3beta.Q54782211
Humoral regulation of red cell productionQ73093468
Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosteroneQ73315959
Glucocorticoid-induced, caspase-dependent organ apoptosis early after burn injuryQ73630833
The extent of osteocyte death in the proximal femur of patients with osteonecrosis of the femoral headQ73848068
Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hipQ74184826
Diagnostic criteria for non-traumatic osteonecrosis of the femoral head. A multicentre studyQ78175836
Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injuryQ81059168
Neuroprotection of erythropoietin and methylprednisolone against spinal cord ischemia-reperfusion injuryQ82261756
Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn woundsQ82583855
Erythropoietin protects critically perfused flap tissueQ83014331
Caspase-3 may be employed as an early predictor for fracture‑induced osteonecrosis of the femoral head in a canine modelQ84464660
Erythropoietin stimulates bone formation, cell proliferation, and angiogenesis in a femoral segmental defect model in miceQ84788674
Changes in Femoral Head Blood Supply and Vascular Endothelial Growth Factor in Rabbits with Steroid-induced OsteonecrosisQ84986001
P433issue4
P921main subjecterythropoietinQ218706
osteonecrosis of the femoral headQ1652102
P304page(s)840-848
P577publication date2014-02-05
P1433published inInternational Journal of Molecular MedicineQ6051492
P1476titleAdministration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats
P478volume33

Reverse relations

cites work (P2860)
Q52692042Animal models of steroid-induced osteonecrosis of the femoral head-a comprehensive research review up to 2018.
Q42874015Bilateral idiopathic osteonecrosis of the femoral head: a case report with an emphasis on differential diagnosis, imaging, and treatment
Q92208788Crocin protects against dexamethasone‑induced osteoblast apoptosis by inhibiting the ROS/Ca2+‑mediated mitochondrial pathway
Q98895939Dual Switch Mechanism of Erythropoietin as an Antiapoptotic and Pro-Angiogenic Determinant in the Retina
Q36148607Effect of SDF-1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury
Q33723789Erythropoietin facilitates the recruitment of bone marrow mesenchymal stem cells to sites of spinal cord injury
Q47329032Erythropoietin induces the osteogenesis of periodontal mesenchymal stem cells from healthy and periodontitis sources via activation of the p38 MAPK pathway
Q91015233Erythropoietin modulates bone marrow stromal cell differentiation
Q51366727Evaluation of the osteogenesis and angiogenesis effects of erythropoietin and the efficacy of deproteinized bovine bone/recombinant human erythropoietin scaffold on bone defect repair.
Q92016330Feature Article: Altered morpho-functional features of bones in autoimmune disease-prone BXSB/MpJ- Yaa mice
Q36477097Glucocorticoids Significantly Influence the Transcriptome of Bone Microvascular Endothelial Cells of Human Femoral Head
Q36148603Lithium chloride attenuates the abnormal osteogenic/adipogenic differentiation of bone marrow-derived mesenchymal stem cells obtained from rats with steroid-related osteonecrosis by activating the β-catenin pathway
Q35856644Nitric oxide content and apoptosis rate in steroid-induced avascular necrosis of the femoral head
Q36592615Protection against ischemia/reperfusion‑induced renal injury by co‑treatment with erythropoietin and sodium selenite
Q93057024Relationship of α2-Macroglobulin with Steroid-Induced Femoral Head Necrosis: A Chinese Population-Based Association Study in Southeast China
Q41818436Research in the precaution of recombinant human erythropoietin to steroid-induced osteonecrosis of the rat femoral head
Q35671575Steroid-induced ischemic bone necrosis of femoral head: Treatment strategies
Q90361703The impact of hypoxic-ischemic brain injury on stem cell mobilization, migration, adhesion, and proliferation
Q52728308Valproic acid prevents glucocorticoid‑induced osteonecrosis of the femoral head of rats.
Q36727078Vitamin K2 Prevents Glucocorticoid-induced Osteonecrosis of the Femoral Head in Rats

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