review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Michael Blaber | |
Maria A Juliano | |||
Hyesook Yoon | |||
Isobel A Scarisbrick | |||
Sachiko I Blaber | |||
P2860 | cites work | Plasmin-platelet interaction involves cleavage of functional thrombin receptor | Q71404326 |
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma | Q73266466 | ||
Stratum corneum tryptic enzyme in normal epidermis: a missing link in the desquamation process? | Q73321995 | ||
Prostatic kallikrein hK2, but not prostate-specific antigen (hK3), activates single-chain urokinase-type plasminogen activator | Q73407627 | ||
Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression | Q22009031 | ||
LEKTI, a novel 15-domain type of human serine proteinase inhibitor | Q22010419 | ||
Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation | Q22010631 | ||
The new human kallikrein gene family: implications in carcinogenesis | Q22253190 | ||
Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4 | Q24290170 | ||
Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region | Q24290448 | ||
Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins | Q24298352 | ||
Proteinase-activated receptors, targets for kallikrein signaling | Q24298638 | ||
LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome | Q24314860 | ||
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14 | Q24316359 | ||
Correlation between SPINK5 gene mutations and clinical manifestations in Netherton syndrome patients | Q46909606 | ||
Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma | Q46934948 | ||
Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR). | Q46959722 | ||
Factor Xa stimulates fibroblast procollagen production, proliferation, and calcium signaling via PAR1 activation | Q47849719 | ||
Proteolytic processing of human growth hormone (GH) by rat tissues in vitro: influence of sex and age. | Q49010216 | ||
Estrogen-dependent expression of the tissue kallikrein gene (Klk1) in the mouse uterus and its implications for endometrial tissue growth. | Q53577758 | ||
Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2. | Q53689045 | ||
Activation profiles and regulatory cascades of the human kallikrein-related peptidases. | Q54434829 | ||
The New Human Tissue Kallikrein Gene Family: Structure, Function, and Association to Disease1 | Q56637802 | ||
Proteolytic processing of human growth hormone by multiple tissue kallikreins and regulation by the serine protease inhibitor Kazal-Type5 (SPINK5) protein | Q57941688 | ||
Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins | Q57941803 | ||
Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy† | Q58011108 | ||
Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice | Q58083211 | ||
Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate | Q69003522 | ||
Cloning and characterization of human protease-activated receptor 4 | Q24322941 | ||
A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation | Q24324426 | ||
SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor | Q24336459 | ||
A proteolytic cascade of kallikreins in the stratum corneum | Q24338337 | ||
Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors | Q28140072 | ||
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome | Q28145552 | ||
Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis | Q28187574 | ||
Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor | Q28188116 | ||
Specificity of coagulation factor signaling | Q28188159 | ||
Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides | Q28204632 | ||
The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions | Q28205501 | ||
Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase | Q28209506 | ||
Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences | Q28243373 | ||
A comprehensive nomenclature for serine proteases with homology to tissue kallikreins | Q28248469 | ||
Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain | Q28249933 | ||
Stratum corneum chymotryptic enzyme: a proteinase which may be generally present in the stratum corneum and with a possible involvement in desquamation | Q28253225 | ||
Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7 | Q28261469 | ||
A dual thrombin receptor system for platelet activation | Q28280578 | ||
The emerging roles of human tissue kallikreins in cancer | Q28290701 | ||
Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression | Q28300449 | ||
Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species | Q28367213 | ||
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma | Q29615947 | ||
The new human tissue kallikrein gene family: structure, function, and association to disease. | Q30328102 | ||
Emerging Interest in the Kallikrein Gene Family for Understanding and Diagnosing Cancer | Q30923168 | ||
Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer. | Q31127351 | ||
Defining the extended substrate specificity of kallikrein 1-related peptidases | Q33304675 | ||
Substrate specificity of human kallikreins 1 and 6 determined by phage display | Q33325124 | ||
Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor | Q33405253 | ||
Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity | Q33715917 | ||
A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15 | Q33726814 | ||
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1. | Q33859268 | ||
Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4. | Q33919333 | ||
Identification and characterization of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains. | Q33932708 | ||
Human tissue kallikrein gene family: a rich source of novel disease biomarkers | Q34119299 | ||
uPAR: a versatile signalling orchestrator | Q34162183 | ||
Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages | Q34223479 | ||
Measurement of Prostate-Specific Antigen in Serum as a Screening Test for Prostate Cancer | Q34577447 | ||
Protease-activated receptor signaling: new roles and regulatory mechanisms | Q34616653 | ||
An overview of the kallikrein gene families in humans and other species: emerging candidate tumour markers | Q35209855 | ||
Human prostate-specific antigen: structural and functional similarity with serine proteases | Q35604260 | ||
Human tissue kallikreins: physiologic roles and applications in cancer. | Q35802061 | ||
Protease-activated receptors in hemostasis, thrombosis and vascular biology | Q36230881 | ||
Emerging insights in tissue factor-dependent signaling events. | Q36396856 | ||
Thrombin generation and the pathogenesis of cancer | Q36467899 | ||
The autolytic regulation of human kallikrein-related peptidase 6. | Q36840687 | ||
Growth Hormone Heterogeneity: Genes, Isohormones, Variants, and Binding Proteins | Q36869909 | ||
Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis | Q36962704 | ||
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa | Q36968186 | ||
Prostate-specific antigen and prostate cancer: prediction, detection and monitoring. | Q37109209 | ||
Functions of KLK4 and MMP-20 in dental enamel formation | Q37207580 | ||
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs). | Q37216570 | ||
Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer | Q37216583 | ||
Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines | Q37217423 | ||
Proteinases as hormones: targets and mechanisms for proteolytic signaling | Q37315770 | ||
Functional roles of human kallikrein-related peptidases | Q37612613 | ||
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. | Q39626396 | ||
Immunofluorometric activity-based probe analysis of active KLK6 in biological fluids | Q39961337 | ||
Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression | Q40007756 | ||
Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs). | Q40262724 | ||
A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein | Q40921349 | ||
Crystallization and preliminary X-ray analysis of neuropsin, a serine protease expressed in the limbic system of mouse brain | Q41117838 | ||
An active zymogen: unravelling the mystery of tissue-type plasminogen activator. | Q41730397 | ||
Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents | Q41845983 | ||
Generation of angiostatin-like fragments from plasminogen by prostate-specific antigen | Q42267377 | ||
Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing | Q43658907 | ||
Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts. | Q44382063 | ||
Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4. | Q44770013 | ||
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation. | Q44979423 | ||
Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression | Q45267227 | ||
PAR1 cleavage and signaling in response to activated protein C and thrombin. | Q46022355 | ||
Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI). | Q46819732 | ||
hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. | Q46819911 | ||
Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects | Q46830854 | ||
P433 | issue | 4 | |
P304 | page(s) | 311-320 | |
P577 | publication date | 2010-04-01 | |
P1433 | published in | Biological Chemistry | Q4914948 |
P1476 | title | Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis | |
P478 | volume | 391 |
Q36560848 | Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6. |
Q39393155 | Human kallikrein-related peptidase 12 (KLK12) splice variants expression in breast cancer and their clinical impact |
Q37579925 | Induction of complement C3a receptor responses by kallikrein-related peptidase 14. |
Q33898347 | Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration |
Q35474479 | Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells |
Q34457491 | Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs). |
Q34256463 | Protease-armed bacteria in the skin |
Q38966192 | Proteinases, Their Extracellular Targets, and Inflammatory Signaling. |
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