Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis

scientific article published on April 2010

Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1515/BC.2010.024
P932PMC publication ID3047482
P698PubMed publication ID20128685
P5875ResearchGate publication ID41403664

P2093author name stringMichael Blaber
Maria A Juliano
Hyesook Yoon
Isobel A Scarisbrick
Sachiko I Blaber
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Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progressionQ28300449
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Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.Q33859268
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Identification and characterization of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains.Q33932708
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The autolytic regulation of human kallikrein-related peptidase 6.Q36840687
Growth Hormone Heterogeneity: Genes, Isohormones, Variants, and Binding ProteinsQ36869909
Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axisQ36962704
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Functions of KLK4 and MMP-20 in dental enamel formationQ37207580
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs).Q37216570
Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancerQ37216583
Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell linesQ37217423
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Functional roles of human kallikrein-related peptidasesQ37612613
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.Q39626396
Immunofluorometric activity-based probe analysis of active KLK6 in biological fluidsQ39961337
Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progressionQ40007756
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A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle proteinQ40921349
Crystallization and preliminary X-ray analysis of neuropsin, a serine protease expressed in the limbic system of mouse brainQ41117838
An active zymogen: unravelling the mystery of tissue-type plasminogen activator.Q41730397
Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodentsQ41845983
Generation of angiostatin-like fragments from plasminogen by prostate-specific antigenQ42267377
Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessingQ43658907
Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts.Q44382063
Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4.Q44770013
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.Q44979423
Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progressionQ45267227
PAR1 cleavage and signaling in response to activated protein C and thrombin.Q46022355
Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI).Q46819732
hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6.Q46819911
Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effectsQ46830854
P433issue4
P304page(s)311-320
P577publication date2010-04-01
P1433published inBiological ChemistryQ4914948
P1476titleFunctional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis
P478volume391

Reverse relations

cites work (P2860)
Q36560848Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6.
Q39393155Human kallikrein-related peptidase 12 (KLK12) splice variants expression in breast cancer and their clinical impact
Q37579925Induction of complement C3a receptor responses by kallikrein-related peptidase 14.
Q33898347Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration
Q35474479Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells
Q34457491Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).
Q34256463Protease-armed bacteria in the skin
Q38966192Proteinases, Their Extracellular Targets, and Inflammatory Signaling.

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