Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

scientific article published on 16 October 2016

Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.12700
P932PMC publication ID5341925
P698PubMed publication ID27756890

P50authorShanshan YuQ82374754
P2093author name stringJiawei Wang
Jingjing Huang
Xi Lu
Lin Lu
Fan Xu
Xiaoling Liang
Yue Xu
Boyu Yang
Yaguang Hu
P2860cites workNeuroprotection in GlaucomaQ26740388
Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric DisordersQ26745690
Retinal Macroglial Responses in Health and DiseaseQ26746666
Current perspective of neuroprotection and glaucomaQ26774852
Neuroprotective therapies in glaucoma: II. Genetic nanotechnology toolsQ26777286
Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injuryQ34137646
Mouse models of retinal ganglion cell death and glaucomaQ34664035
Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time- and dose-dependent manner in ratsQ34764850
Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammationQ35262027
The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal InflammationQ35895350
Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucomaQ36071513
Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB.Q36317535
Bilateral neuroinflammatory processes in visual pathways induced by unilateral ocular hypertension in the ratQ36599983
Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration?Q37827535
Polyphenols and neuroprotection against ischemia and neurodegenerationQ37954434
The molecular basis of retinal ganglion cell death in glaucomaQ37966513
Neuroprotection in glaucoma: present and futureQ38099770
Interconnection between brain and retinal neurodegenerationsQ38211671
Evidence That Erythropoietin Modulates Neuroinflammation through Differential Action on Neurons, Astrocytes, and MicrogliaQ38265508
Neuroprotective therapies in glaucoma: I. Neurotrophic factor deliveryQ38573732
Neuroinflammation in Glaucoma and Optic Nerve DamageQ38574387
Macro- and microglial responses in the fellow eyes contralateral to glaucomatous eyes.Q38615511
The Role of Long Noncoding RNAs in Neurodegenerative Diseases.Q38748575
RETINAL VASCULAR CYSTOID MACULAR EDEMA: Review and New TheoryQ38872179
Neuroinflammation pathways: a general reviewQ38895785
Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cellsQ38937095
Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cellsQ39164977
Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells.Q39202269
Up-regulation of Wip1 involves in neuroinflammation of retinal astrocytes after optic nerve crush via NF-κB signaling pathwayQ39748414
Ketorolac Administration Attenuates Retinal Ganglion Cell Death After Axonal InjuryQ39922042
Apoptotic Retinal Ganglion Cell Death After Optic Nerve Transection or Crush in Mice: Delayed RGC Loss With BDNF or a Caspase 3 InhibitorQ40094329
Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.Q40143788
Prothymosin-alpha preconditioning activates TLR4-TRIF signaling to induce protection of ischemic retinaQ41002934
GRP75 Involves in Retinal Ganglion Cell Apoptosis After Rat Optic Nerve CrushQ41561595
Upregulation of CREM-1 relates to retinal ganglion cells apoptosis after light-induced damage in vivo.Q44527543
Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cellsQ44751866
Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusionQ45092194
Effect of brain-derived neurotrophic factor on mouse axotomized retinal ganglion cells and phagocytic microgliaQ46097407
Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activityQ46412530
Wogonin prevents rat dorsal root ganglion neurons death via inhibiting tunicamycin-induced ER stress in vitroQ48461468
Glutamate Inhibits the Pro-Survival Effects of Insulin-Like Growth Factor-1 on Retinal Ganglion Cells in Hypoxic Neonatal Rat Retina.Q48736068
Therapeutic Retrobulbar Inhibition of STAT3 Protects Ischemic Retina Ganglion Cells.Q51040094
siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms.Q52885910
CD200Fc reduces TLR4-mediated inflammatory responses in LPS-induced rat primary microglial cells via inhibition of the NF-κB pathway.Q53155339
Toll-like receptor-4 knockout mice are more resistant to optic nerve crush damage than wild-type mice.Q53585154
Caspase-3 inhibitor Z-DEVD-FMK enhances retinal ganglion cell survival and vision restoration after rabbit traumatic optic nerve injury.Q53644251
Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway.Q53669008
Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway.Q55070103
Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats.Q55073618
Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injuryQ61757974
Anticancer properties of the flavone wogoninQ87340528
The expression changes of myelin and lymphocyte protein (MAL) following optic nerve crush in adult rats retinal ganglion cellsQ87986393
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
toll-like receptorQ408004
wogoninQ409606
NF-κBQ411114
retinal ganglion cellQ927337
P304page(s)72503-72517
P577publication date2016-10-16
P1433published inOncotargetQ1573155
P1476titleWogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush
P478volume7

Reverse relations

cites work (P2860)
Q92716024Associations between TLR4 Polymorphisms and Open Angle Glaucoma: A Meta-Analysis
Q47252786CD200Fc Attenuates Retinal Glial Responses and RGCs Apoptosis After Optic Nerve Crush by Modulating CD200/CD200R1 Interaction
Q64937596Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death.
Q47700181Cell activity during peripheral nerve defect repair process using a nerve scaffold
Q92488295Dexmedetomidine Post-Conditioning Alleviates Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting High Mobility Group Protein B1 Group (HMGB1)/Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling Pathway
Q47951826Inhibition of TLR4 alleviates the inflammation and apoptosis of retinal ganglion cells in high glucose.
Q90605831Kaempferol attenuates retinal ganglion cell death by suppressing NLRP1/NLRP3 inflammasomes and caspase-8 via JNK and NF-κB pathways in acute glaucoma
Q91807499Protective Efficacy of a Dietary Supplement Based on Forskolin, Homotaurine, Spearmint Extract, and Group B Vitamins in a Mouse Model of Optic Nerve Injury
Q54940884Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Q97536785Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro
Q90278209Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade
Q58760376lectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway

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