The role of B cell depleting therapy in graft versus host disease after allogeneic hematopoietic cell transplant

scientific article published on 08 February 2010

The role of B cell depleting therapy in graft versus host disease after allogeneic hematopoietic cell transplant is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3109/10428190903586318
P698PubMed publication ID20141428

P2093author name stringVoravit Ratanatharathorn
Amin M Alousi
Joseph Uberti
P2860cites workMinor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantationQ24537575
Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remissionQ24539030
Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell-depleting therapy with rituximabQ28274444
The biology of CD20 and its potential as a target for mAb therapyQ28295215
Drug insight: the mechanism of action of rituximab in autoimmune disease--the immune complex decoy hypothesisQ30442932
Anti-CD20 chimeric monoclonal antibody treatment of refractory immune-mediated thrombocytopenia in a patient with chronic graft-versus-host diseaseQ33333428
Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura.Q33338442
Treatment of refractory chronic GVHD with rituximab: a GITMO study.Q33375484
Rituximab for the treatment of corticosteroid-refractory chronic graft-versus-host diseaseQ33385079
Translational Mini-Review Series on B Cell-Directed Therapies: Recent advances in B cell-directed biological therapies for autoimmune disordersQ33385389
Autoantibodies in human chronic graft-versus-host disease after hematopoietic cell transplantationQ33603172
Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-toleranceQ33749097
High levels of B-cell activating factor in patients with active chronic graft-versus-host diseaseQ34135089
Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantationQ34186689
The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.Q34540035
B cells move to centre stage: novel opportunities for autoimmune disease treatmentQ34544062
BAFF: a fundamental survival factor for B cells.Q34718112
Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host diseaseQ34791351
Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot studyQ34897189
Expression of costimulatory molecules on peripheral blood lymphocytes of patients with systemic lupus erythematosusQ35550436
Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistanceQ35567244
Dry eye as a major complication associated with chronic graft-versus-host disease after hematopoietic stem cell transplantationQ35619625
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host diseaseQ35848361
Rituximab for steroid-refractory chronic graft-versus-host diseaseQ35848933
Prior rituximab correlates with less acute graft-versus-host disease and better survival in B-cell lymphoma patients who received allogeneic peripheral blood stem cell transplantationQ35970489
Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host diseaseQ36141721
Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximabQ36219690
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrowQ36342244
Development of graft-vs.-host disease-like syndrome in cyclosporine-treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivityQ36355418
Pathophysiology of graft-versus-host diseaseQ36368101
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
Murine models of chronic graft-versus-host disease: insights and unresolved issuesQ36645730
Reduced-intensity regimens in allogeneic stem-cell transplantation for non-hodgkin lymphoma and chronic lymphocytic leukemiaQ36662259
Pharmacokinetics of rituximab and its clinical use: thought for the best use?Q36730842
In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host diseaseQ36843821
Mechanisms of killing by anti-CD20 monoclonal antibodies.Q36927853
Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunityQ36990647
Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosusQ36993242
A unique cell surface antigen identifying lymphoid malignancies of B cell originQ37025725
Molecular framework for response to imatinib mesylate in systemic sclerosis.Q37088947
Risk factors for acute graft-versus-host disease after human leukocyte antigen-identical sibling transplants for adults with leukemiaQ37104236
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host diseaseQ37162874
GVHD pathophysiology: is acute different from chronic?Q37173437
Newer monoclonal antibodies for hematological malignancies.Q37195353
The role of complement in the mechanism of action of rituximab for B-cell lymphoma: implications for therapyQ37263773
Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody productionQ37354525
Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytesQ37358432
Imatinib mesylate as salvage therapy for refractory sclerotic chronic graft-versus-host diseaseQ37511121
Efficacy of rituximab in the setting of steroid-refractory chronic graft-versus-host disease: a systematic review and meta-analysisQ37574510
Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritisQ40119794
Mouse CD20 expression and functionQ40605430
The role of CD40 ligand in costimulation and T-cell activationQ41332099
Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cellsQ42079747
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapyQ42971266
Chronic graft-versus-host disease after allogeneic blood stem cell transplantationQ43727815
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphomaQ43864036
Nonablative allogeneic stem-cell transplantation for advanced/recurrent mantle-cell lymphomaQ44674126
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeksQ44774931
Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphomaQ44905104
CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphomaQ45115068
Imatinib for refractory chronic graft-versus-host disease with fibrotic features.Q46031486
A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: the first fifty patientsQ46067913
Isolation and characterization of the B-cell marker CD20.Q46351260
Rituximab improves the treatment results of DHAP-VIM-DHAP and ASCT in relapsed/progressive aggressive CD20+ NHL: a prospective randomized HOVON trialQ46923089
Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcomeQ47359749
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.Q47365613
Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestationsQ47605536
Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.Q47775652
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection.Q50796687
Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6.Q51965126
Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE.Q51978495
In vivo CD86 blockade inhibits CD4+ T cell activation, whereas CD80 blockade potentiates CD8+ T cell activation and CTL effector function.Q52013494
Splenic B cells function as immunogenic antigen-presenting cells for the induction of effector T cells.Q52216973
Defective induction of antigen-reactive proliferating T cells in B cell-deprived mice. II. Anti-mu treatment affects the initiation and recruitment of T cells.Q52216986
Role of B cells as antigen-presenting cells in vivo revisited: antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations.Q52544618
Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD.Q52935953
Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma.Q53497567
The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery.Q53632072
Bone marrow transplantation from unrelated donors: the impact of mismatches with substitutions at position 116 of the human leukocyte antigen class I heavy chainQ56877667
Identification of a graft versus host disease-associated human minor histocompatibility antigenQ56929110
Donor-derived thymic-dependent T cells cause chronic graft-versus-host diseaseQ57917586
Altered Toll-Like Receptor 9 Responses in Circulating B Cells at the Onset of Extensive Chronic Graft-versus-Host DiseaseQ59094143
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)376-389
P577publication date2010-02-08
P1433published inLeukemia & LymphomaQ6534493
P1476titleThe role of B cell depleting therapy in graft versus host disease after allogeneic hematopoietic cell transplant
P478volume51

Reverse relations

cites work (P2860)
Q37899200B cell homeostasis and the development of chronic graft-versus-host disease: implications for B cell-depleting therapy
Q37923305Bronchiolitis obliterans after allo-SCT: clinical criteria and treatment options.
Q50143234Effect of Rituximab on Pulmonary Function in Bronchiolitis Obliterans Syndrome due to Graft-Versus-Host-Disease
Q38226527Extracorporeal photopheresis (photochemotherapy) in the treatment of acute and chronic graft versus host disease: immunological mechanisms and the results from clinical studies
Q42203241In vitro effects of different 8-methoxypsoralen treatment protocols for extracorporeal photopheresis on mononuclear cells
Q27307168In vivo depletion of lymphotoxin-alpha expressing lymphocytes inhibits xenogeneic graft-versus-host-disease
Q64882848Myasthenia Gravis Presenting as Graft versus Host Disease after Allogeneic Blood Stem Cell Transplant.
Q34202277NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantatio
Q36159937Overview of T-cell depletion in haploidentical stem cell transplantation
Q33396969Renal thrombotic microangiopathy associated with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Q34622755Strategies to Prevent EBV Reactivation and Posttransplant Lymphoproliferative Disorders (PTLD) after Allogeneic Stem Cell Transplantation in High-Risk Patients
Q44282314Successful treatment of severe myasthenia gravis developed after allogeneic hematopoietic stem cell transplantation with plasma exchange and rituximab.
Q39460016The effect of lentivirus-mediated expression of tumor necrosis factor related apoptosis-inducing ligand and shRNA against Bcl-2 on the growth of lymphoma cells
Q82152061The humanized anti-HLA-DR moAb, IMMU-114, depletes APCs and reduces alloreactive T cells: implications for preventing GVHD
Q35084404The pathophysiology of chronic graft-versus-host disease: the unveiling of an enigma
Q38392246Therapeutic benefits targeting B-cells in chronic graft-versus-host disease
Q26851433Treatment of chronic graft-versus-host disease in 2011

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