| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Marton Keszei | Q45406796 |
| P2093 | author name string | Cox Terhorst | |
| Cynthia Detre | |||
| Xavier Romero | |||
| George C Tsokos | |||
| P2860 | cites work | Mapping autoimmune disease genes in humans: lessons from IBD and SLE | Q81928627 |
| The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM | Q22003958 | ||
| Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition | Q22010755 | ||
| Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP | Q24291284 | ||
| Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients | Q24291489 | ||
| A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome | Q24292245 | ||
| SAP couples Fyn to SLAM immune receptors | Q24293203 | ||
| SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells | Q24297438 | ||
| The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation | Q24303904 | ||
| Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity | Q24306586 | ||
| Molecular cloning of the lymphocyte activation marker Blast-1 | Q24339640 | ||
| Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells | Q24535874 | ||
| Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease | Q24536218 | ||
| Follicular helper T cells: lineage and location | Q24647274 | ||
| The role of NKT cells in tumor immunity | Q24648939 | ||
| Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice | Q24799092 | ||
| Structure of CD84 provides insight into SLAM family function | Q27645635 | ||
| The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2) | Q28181256 | ||
| Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family | Q28203554 | ||
| X-linked lymphoproliferative disease: a progressive immunodeficiency | Q28204385 | ||
| The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease | Q28206630 | ||
| XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome | Q28271832 | ||
| The biology of NKT cells | Q28277482 | ||
| Expression of the Blast-1 activation/adhesion molecule and its identification as CD48 | Q28280431 | ||
| NKT cells derive from double-positive thymocytes that are positively selected by CD1d | Q28508188 | ||
| Genomic organization and characterization of mouse SAP, the gene that is altered in X-linked lymphoproliferative disease | Q28511409 | ||
| Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development | Q28584820 | ||
| Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor | Q28585941 | ||
| SAP is required for generating long-term humoral immunity | Q28588045 | ||
| SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9. | Q30164163 | ||
| Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation | Q30164947 | ||
| Genetics of type 1A diabetes | Q30448199 | ||
| Invariant NKT cells sustain specific B cell responses and memory | Q30479030 | ||
| Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells | Q33700550 | ||
| Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP | Q33879986 | ||
| Defective B cell responses in the absence of SH2D1A | Q33935159 | ||
| The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes | Q34104677 | ||
| Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. | Q34144312 | ||
| Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors | Q34150421 | ||
| A major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31 | Q34153866 | ||
| Delineating the genetic basis of systemic lupus erythematosus | Q34376876 | ||
| Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. | Q34416740 | ||
| NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family | Q34574420 | ||
| The SLAM and SAP gene families control innate and adaptive immune responses. | Q34781617 | ||
| Genetics and pathogenesis of multiple sclerosis | Q35004746 | ||
| ITK and IL-15 support two distinct subsets of CD8+ T cells | Q35033191 | ||
| Lupus susceptibility loci in New Zealand mice | Q35836652 | ||
| Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia | Q35845861 | ||
| Going both ways: immune regulation via CD1d-dependent NKT cells | Q35951531 | ||
| Follicular helper T cells as cognate regulators of B cell immunity | Q37510254 | ||
| X-linked recessive progressive combined variable immunodeficiency (Duncan's disease) | Q39324844 | ||
| Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development | Q39569415 | ||
| Differential requirement for the SAP-Fyn interaction during NK T cell development and function | Q39953297 | ||
| Regulation of B cell tolerance by the lupus susceptibility gene Ly108. | Q40267209 | ||
| Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice | Q40388457 | ||
| Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244). | Q40457804 | ||
| Lysosomal glycosphingolipid recognition by NKT cells | Q40493118 | ||
| Dynamic redistribution of the activating 2B4/SAP complex at the cytotoxic NK cell immune synapse | Q40517805 | ||
| Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia | Q40635781 | ||
| Aberrant DAP12 signaling in the 129 strain of mice: implications for the analysis of gene-targeted mice | Q40712509 | ||
| Malignant lymphoma in the X-linked lymphoproliferative syndrome | Q40797813 | ||
| X-linked lymphoproliferative disease: twenty-five years after the discovery | Q40944318 | ||
| Active and passive experimental autoimmune encephalomyelitis in strain 129/J (H-2b) mice | Q41174668 | ||
| Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families | Q41612386 | ||
| Documentation of Burkitt lymphoma with t(8;14) (q24;q32) in X-linked lymphoproliferative disease | Q41983081 | ||
| The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction | Q42576920 | ||
| Confirmation of genetic linkage between human systemic lupus erythematosus and chromosome 1q41. | Q42611334 | ||
| Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus. | Q42687796 | ||
| Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development | Q42944908 | ||
| The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression | Q43194838 | ||
| Fasciola hepatica infection downregulates Th1 responses in mice. | Q43514231 | ||
| CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells. | Q43622854 | ||
| SAP controls T cell responses to virus and terminal differentiation of TH2 cells. | Q43692363 | ||
| The absence of Itk inhibits positive selection without changing lineage commitment | Q44021498 | ||
| The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. | Q44155406 | ||
| Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation. | Q45147807 | ||
| Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus | Q45180946 | ||
| Analysis of SH2D1A mutations in patients with severe Epstein-Barr virus infections, Burkitt's lymphoma, and Hodgkin's lymphoma | Q45730987 | ||
| Correlation of mutations of the SH2D1A gene and epstein-barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease. | Q45740032 | ||
| NKT-cell help to B lymphocytes can occur independently of cognate interaction. | Q45880618 | ||
| Association of LY9 in UK and Canadian SLE families | Q46742866 | ||
| A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice | Q46859596 | ||
| Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions | Q47800852 | ||
| CD1d1-dependent control of the magnitude of an acute antiviral immune response | Q47991973 | ||
| Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. | Q50930741 | ||
| NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner. | Q51821741 | ||
| The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. | Q51980787 | ||
| Loss of circulating CD27+ memory B cells and CCR4+ T cells occurring in association with elevated EBV loads in XLP patients surviving primary EBV infection | Q52004511 | ||
| Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. | Q52915840 | ||
| SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. | Q53579591 | ||
| SAP is required for Th cell function and for immunity to influenza. | Q53595803 | ||
| Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells. | Q53612045 | ||
| Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. | Q53616648 | ||
| EBV-induced human CD8+ NKT cells suppress tumorigenesis by EBV-associated malignancies. | Q54461022 | ||
| Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. | Q54626090 | ||
| CD1d antigen presentation: treats for NKT cells | Q56917516 | ||
| Genetic Dissection of Spontaneous Autoimmunity Driven by 129-Derived Chromosome 1 Loci When Expressed on C57BL/6 Mice | Q57089462 | ||
| Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice | Q57089590 | ||
| Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions | Q58328314 | ||
| Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP | Q63226059 | ||
| Amelioration of experimental systemic lupus erythematosus (SLE) by retrovirus infection | Q71612543 | ||
| IL-5 and Rp105 signaling defects in B cells from commonly used 129 mouse substrains | Q73201942 | ||
| Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome | Q74420409 | ||
| Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus | Q79333229 | ||
| Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death | Q79696856 | ||
| Antibody class switching differs among SJL, C57BL/6 and 129 mice | Q79847353 | ||
| PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr | Q79974102 | ||
| Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c | Q80345175 | ||
| SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1 | Q80991137 | ||
| An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population | Q81354592 | ||
| Regulation of NKT cell development by SAP, the protein defective in XLP | Q81402277 | ||
| Genetic determination of T cell help in loss of tolerance to nuclear antigens | Q81827351 | ||
| Signaling for NKT cell development: the SAP-FynT connection | Q36076597 | ||
| SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation | Q36228622 | ||
| Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP | Q36310561 | ||
| Genetics of T cell defects in lupus | Q36373642 | ||
| The Src family tyrosine kinase Fyn regulates natural killer T cell development | Q36375458 | ||
| The cell surface receptor SLAM controls T cell and macrophage functions | Q36399495 | ||
| SH2D1A regulates T-dependent humoral autoimmunity | Q36399879 | ||
| Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product | Q36402758 | ||
| Requirement for CD1d expression by B cells to stimulate NKT cell-enhanced antibody production | Q36445859 | ||
| Autoimmunity in systemic lupus erythematosus: integrating genes and biology | Q36483710 | ||
| Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17 | Q36502818 | ||
| Requirements for selection of conventional and innate T lymphocyte lineages | Q36648754 | ||
| Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development | Q36811142 | ||
| Immunological and genetic bases of new primary immunodeficiencies | Q36981181 | ||
| NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis | Q36982958 | ||
| Natural killer T cells and X-linked lymphoproliferative syndrome | Q36995956 | ||
| SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation | Q37001206 | ||
| T follicular helper (TFH) cells in normal and dysregulated immune responses | Q37049341 | ||
| Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis | Q37087428 | ||
| SAP-controlled T-B cell interactions underlie germinal centre formation | Q37119530 | ||
| Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities | Q37129666 | ||
| The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development | Q37158945 | ||
| Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk | Q37171086 | ||
| Follicular helper T cells are required for systemic autoimmunity | Q37234304 | ||
| The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease | Q37274351 | ||
| X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses | Q37278914 | ||
| Rheumatoid arthritis: a view of the current genetic landscape | Q37315484 | ||
| Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP). | Q37348054 | ||
| SLAM receptors and SAP influence lymphocyte interactions, development and function | Q37349689 | ||
| Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation | Q37358144 | ||
| Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. | Q37363074 | ||
| Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus | Q37363440 | ||
| Innate-like recognition of microbes by invariant natural killer T cells | Q37398859 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 157-171 | |
| P577 | publication date | 2010-02-10 | |
| P1433 | published in | Seminars in Immunopathology | Q15724576 |
| P1476 | title | SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions | |
| P478 | volume | 32 |
| Q90254584 | 2B4 Mediates Inhibition of CD8+ T Cell Responses via Attenuation of Glycolysis and Cell Division |
| Q50533096 | A CD8α- Subset of CD4+ SLAMF7+ Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment. |
| Q38794091 | A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education. |
| Q35102250 | A novel isoform of the Ly108 gene ameliorates murine lupus. |
| Q28115070 | A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activation |
| Q35092855 | Abnormalities of T cell signaling in systemic lupus erythematosus |
| Q40775934 | Allelic expression imbalance polymorphisms in susceptibility chromosome regions and the risk and survival of breast cancer |
| Q92735504 | BCL-6 suppresses miR-142-3p/5p expression in SLE CD4+ T cells by modulating histone methylation and acetylation of the miR-142 promoter |
| Q36368306 | CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORγt recruitment to the IL17A promoter in human T lymphocytes |
| Q28081315 | Coevolution of MHC genes (LMP/TAP/class Ia, NKT-class Ib, NKp30-B7H6): lessons from cold-blooded vertebrates |
| Q35825797 | Correlative studies on the effects of obesity, diabetes and hypertension on gene expression in omental adipose tissue of obese women |
| Q28588043 | Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse |
| Q27329902 | Cytomegalovirus m154 hinders CD48 cell-surface expression and promotes viral escape from host natural killer cell control |
| Q37952177 | Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation |
| Q36971202 | Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production |
| Q54312096 | Decreased microRNA-142-3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus. |
| Q34116824 | Development and characterization of domain-specific monoclonal antibodies produced against human SLAMF9 |
| Q37689394 | EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization. |
| Q55310350 | Elotuzumab for the Treatment of Relapsed or Refractory Multiple Myeloma, with Special Reference to its Modes of Action and SLAMF7 Signaling. |
| Q42705255 | Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus |
| Q38111622 | Gene-function studies in systemic lupus erythematosus. |
| Q92734901 | Immune Relevant and Immune Deficient Mice: Options and Opportunities in Translational Research |
| Q24632664 | Immunodeficiency and autoimmunity: lessons from systemic lupus erythematosus |
| Q42151219 | Integrated copy number and gene expression profiling analysis of Epstein-Barr virus-positive diffuse large B-cell lymphoma |
| Q36183169 | Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility |
| Q37057979 | Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens. |
| Q46300761 | Measles Vaccine |
| Q38714305 | Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway |
| Q40197875 | Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses |
| Q42229053 | SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8+ T Cells with Innate Lymphocyte Characteristics |
| Q36079768 | SAP expression in invariant NKT cells is required for cognate help to support B-cell responses |
| Q41832753 | SAP modulates B cell functions in a genetic background-dependent manner |
| Q92129398 | SLAM receptors foster iNKT cell development by reducing TCR signal strength after positive selection |
| Q64096305 | SLAM-ing the brakes on iNKT cell selection |
| Q98623775 | SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2 |
| Q89981008 | SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint |
| Q50069715 | SLE-Associated Defects Promote Altered T Cell Function |
| Q64092279 | Serum biomarker panels for the diagnosis of gastric cancer |
| Q58785647 | Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions |
| Q40376398 | Signaling Lymphocytic Activation Molecule Family Member 7 Engagement Restores Defective Effector CD8+ T Cell Function in Systemic Lupus Erythematosus. |
| Q52584346 | Signaling lymphocytic activation molecules Slam and cancers: friends or foes? |
| Q37184787 | Simultaneous TCR and CD244 signals induce dynamic downmodulation of CD244 on human antiviral T cells. |
| Q90613288 | The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus |
| Q30010025 | The adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling |
| Q30529641 | The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner |
| Q41636146 | Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation. |
| Q28740832 | Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses |
| Q35747417 | Wild-Type Measles Virus is Intrinsically Dual-Tropic. |
| Q42063701 | Wild-type measles virus interferes with short-term engraftment of human CD34+ hematopoietic progenitor cells |
| Q27690253 | X-linked lymphoproliferative syndromes: brothers or distant cousins? |
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