Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs

scientific article published on 05 January 2008

Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXPNEUROL.2007.12.019
P932PMC publication ID3979422
P698PubMed publication ID18291370

P2093author name stringJun Zhang
Douglas H Smith
David F Meaney
Xiao-Han Chen
Rasmus Rojkjaer
Sherman C Stein
Victoria E Johnson
Kevin D Browne
Jason Huang
Robert F Groff
Eric D Schwartz
P2860cites workSerine proteases and brain damage - is there a link?Q30305943
The role of platelets and recombinant factor VIIa on thrombin generation, platelet activation and clot formationQ33360627
Recombinant activated factor VII for acute intracerebral hemorrhage.Q34397275
Diffuse axonal injury in head traumaQ34459202
Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathyQ34522223
The use of recombinant factor VIIa in controlling surgical bleeding in non-haemophiliac patientsQ34817997
Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain traumaQ35103035
A cell-based model of coagulation and the role of factor VIIaQ35617165
Moderate and severe traumatic brain injury: epidemiologic, imaging and neuropathologic perspectivesQ35802472
Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleedingQ35839531
Delayed brain injury after head trauma: significance of coagulopathyQ35905754
Coagulopathy in traumatic brain injuryQ36262718
Preclinical trauma studies of recombinant factor VIIaQ36284643
Effects of recombinant activated factor VII in traumatic nonsurgical intracranial hemorrhageQ36592943
Diffuse axonal injury in non-missile head injuryQ37274633
Safety and feasibility of recombinant factor VIIa for acute intracerebral hemorrhage.Q40519948
Recombinant activated factor VII in children with acute bleeding resulting from liver failure and disseminated intravascular coagulation.Q40620271
Guidelines for the management of severe head injury. Brain Trauma FoundationQ41348510
Binding of alpha-thrombin to fibrin depends on the quality of the fibrin networkQ41909182
Progressive hemorrhage after head trauma: predictors and consequences of the evolving injuryQ43856783
Recombinant activated factor VII for adjunctive hemorrhage control in traumaQ44472174
Disseminated intravascular coagulation associated with massive brain injuryQ44545125
Venous thromboembolism prophylaxis after head and spinal trauma: intermittent pneumatic compression devices versus low molecular weight heparinQ45085263
Factor VIIa for correction of traumatic coagulopathyQ45130198
Possible role of recombinant activated factor VII (rFVIIa) in the control of hemorrhage associated with massive trauma.Q45858062
The Effect of Recombinant Factor VIIa on Noncoagulopathic Pigs with Grade V Liver InjuriesQ45862242
The role of recombinant factor VIIa (FVIIa) in fibrin structure in the absence of FVIII/FIX.Q45863825
Preferential localization of recombinant factor VIIa to platelets activated with a combination of thrombin and a glycoprotein VI receptor agonistQ45865116
Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A.Q45882175
Recombinant factor VIIa for the treatment of severe postoperative and traumatic hemorrhageQ45882217
Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: a report by the Israeli Multidisciplinary rFVIIa Task ForceQ45882922
Platelet activity of high-dose factor VIIa is independent of tissue factorQ45884609
The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuriesQ45888438
Breakdown of the blood-brain barrier after fluid percussive brain injury in the rat. Part 1: Distribution and time course of protein extravasationQ46304244
Breakdown of the Blood–Brain Barrier After Fluid Percussion Brain Injury in the Rat: Part 2: Effect of Hypoxia on Permeability to Plasma ProteinsQ46576120
Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury periodQ46954679
Plasminogen activators potentiate thrombin-induced brain injuryQ47976056
MR imaging of experimentally induced intracranial hemorrhage in rabbits during the first 6 hoursQ48170509
Hematoma enlargement in spontaneous intracerebral hemorrhageQ48197733
Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformationQ48277556
Modulation of hippocampal neuron survival by thrombin and factor Xa.Q48358999
Delayed and progressive brain injury in closed-head trauma: radiological demonstrationQ48363389
Dynamics of intraventricular hemorrhage in patients with spontaneous intracerebral hemorrhage: risk factors, clinical impact, and effect of hemostatic therapy with recombinant activated factor VII.Q48397525
MR follow-up of small experimental intracranial haemorrhages from hyperacute to subacute phaseQ48623285
Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pigQ48675620
Head-injured patients who talk and deteriorate into coma. Analysis of 211 cases studied with computerized tomographyQ48675734
Treatment of severe coagulopathy after gunshot injury to the head using recombinant activated factor VII.Q48791426
Early hemorrhage growth in patients with intracerebral hemorrhageQ48821770
Factors associated with neurological outcome and lesion progression in traumatic subarachnoid hemorrhage patients.Q48953684
Antiapoptotic effect of coagulation factor VIIa.Q51837430
Mannitol pharmacokinetics and serum osmolality in dogs and humans.Q52429650
Traumatic brain injuryQ54273190
Treatment of traumatic bleeding with recombinant factor VIIa.Q55033461
A prospective study of venous thromboembolism after major trauma.Q55065749
Effective Management of Refractory Postcardiotomy Bleeding With the Use of Recombinant Activated Factor VIIQ59259297
Traumatic Brain Injury in the United States: A Public Health PerspectiveQ61424636
Evolving brain lesions in the first 12 hours after head injury: analysis of 37 comatose patientsQ70894547
Fibrin in human plasma: gel architectures governed by rate and nature of fibrinogen activationQ72887288
Sequential computerized tomography changes and related final outcome in severe head injury patientsQ73468538
Immediate coma following inertial brain injury dependent on axonal damage in the brainstemQ74125872
Control of life-threatening pulmonary bleeding with activated recombinant factor VIIQ77763143
Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trialQ78840677
Detection and appearance of intraparenchymal haematomas of the brain at 1.5 T with spin-echo, FLAIR and GE sequences: poor relationship to the age of the haematomaQ80076066
Recombinant factor VIIa increases the pressure at which rebleeding occurs in porcine uncontrolled aortic hemorrhage modelQ80347296
Effects of increasing doses of activated recombinant factor VII on haemostatic parameters in swineQ81402653
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjecttraumatic brain injuryQ1995526
P304page(s)645-655
P577publication date2008-01-05
P1433published inExperimental NeurologyQ5421127
P1476titleHemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs
P478volume210

Reverse relations

cites work (P2860)
Q41356124A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration
Q33694285Age Is a Determinant of Leukocyte Infiltration and Loss of Cortical Volume after Traumatic Brain Injury
Q39203875An in vivo, MRI-integrated real-time model of active contrast extravasation in acute intracerebral hemorrhage
Q35589949Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?
Q27025951Animal models of traumatic brain injury
Q30476151Assessing learning and memory in pigs
Q30739121Diffusion tensor imaging and magnetic resonance spectroscopy in traumatic brain injury: a review of recent literature
Q88687080Factor VIIa administration in traumatic brain injury: an AAST-MITC propensity score analysis
Q95790496Folic acid enhances early functional recovery in a piglet model of pediatric head injury
Q35212583Mild traumatic brain injury and diffuse axonal injury in swine
Q30968544Pre-Clinical Traumatic Brain Injury Common Data Elements: Toward a Common Language Across Laboratories
Q39611127The influence of coagulation and inflammation research on the improvement of polytrauma care
Q64082897The pig as a preclinical traumatic brain injury model: current models, functional outcome measures, and translational detection strategies
Q36768885Therapy development for diffuse axonal injury
Q33581052Use of recombinant factor VIIa (rFVIIa) as pre-hospital treatment in a swine model of fluid percussion traumatic brain injury
Q84509682[Use of activated recombinant factor VII in patients with brain injury or undergoing brain surgery]

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