Influence of Cyp2c19*2 Gene Variant on Therapeutic Response During Clopidogrel Treatment in Patients with Carotid Artery Stenosis

scientific article published on 30 December 2015

Influence of Cyp2c19*2 Gene Variant on Therapeutic Response During Clopidogrel Treatment in Patients with Carotid Artery Stenosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1515/JOMB-2015-0009
P932PMC publication ID5346798
P698PubMed publication ID28356861

P50authorJelena S Kusic-TismaQ84523977
P2093author name stringBranko Čalija
Ðorđe Radak
Dragana Bačković
Dragica Radojković
Evgenija Strugarević
Ljiljana Rakićević
Mirjana Kovač
Svetlana Ignjatović
P2860cites workGenetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients.Q50946747
Impact of point-of-care testing for CYP2C19 on platelet inhibition in patients with acute coronary syndrome and early dual antiplatelet therapy in the emergency settingQ56770154
Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: the PEGASUS-PCI studyQ58071120
Impact of high post-loading platelet aggregation on 30-day clinical outcomes after primary percutaneous coronary intervention. The antiplatelet regimen tailoring after primary PCI (ART-PCI) trialQ84211092
Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery diseaseQ87056362
[Statin and clopidogrel pharmacological interaction]Q87175621
Pharmacokinetic drug interactions with clopidogrel: updated review and risk management in combination therapyQ26852535
High platelet reactivity on clopidogrel therapy correlates with increased coronary atherosclerosis and calcification: a volumetric intravascular ultrasound studyQ30450312
Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stentsQ33335010
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapyQ34019082
The role of clinical parameters and of CYP2C19 G681 and CYP4F2 G1347A polymorphisms on platelet reactivity during dual antiplatelet therapyQ34397563
Genetic determinants of response to clopidogrel and cardiovascular eventsQ34910210
Cytochrome p-450 polymorphisms and response to clopidogrelQ34910228
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery diseaseQ37259929
Pharmacogenomics of clopidogrel: evidence and perspectivesQ37876990
The pharmacogenetics of antiplatelet agents: towards personalized therapy?Q37913976
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysisQ37971875
Response variability to clopidogrel: is tailored treatment, based on laboratory testing, the right solution?Q37973457
Pharmacogenomics in cardiovascular disease: focus on aspirin and ADP receptor antagonistsQ38117748
Genetics of platelet inhibitor treatmentQ38131848
Clinical implications of drug-drug interactions with P2Y12 receptor inhibitorsQ38177048
Antithrombotic therapy in carotid artery stenosis: an updateQ38268760
Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: a 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrQ42857052
Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapyQ43057001
Platelet responsiveness to clopidogrel treatment after peripheral endovascular procedures: the PRECLOP study: clinical impact and optimal cutoff value of on-treatment high platelet reactivityQ43643299
Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome.Q45947797
Relationship between CYP2C19 loss-of-function polymorphism and platelet reactivities with clopidogrel treatment in Japanese patients undergoing coronary stent implantationQ46784167
The use of amlodipine, but not of P-glycoprotein inhibiting calcium channel blockers is associated with clopidogrel poor-responseQ50199244
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 4.0 InternationalQ24082749
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectclopidogrelQ410237
carotid artery stenosisQ1576205
P304page(s)26-33
P577publication date2015-12-30
P1433published inJournal of Medical BiochemistryQ15766602
P1476titleInfluence of Cyp2c19*2 Gene Variant on Therapeutic Response During Clopidogrel Treatment in Patients with Carotid Artery Stenosis
P478volume35

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