Antimicrobial peptide LL-37 promotes YB-1 expression, and the viability, migration and invasion of malignant melanoma cells

scientific article published on 02 December 2016

Antimicrobial peptide LL-37 promotes YB-1 expression, and the viability, migration and invasion of malignant melanoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2016.5978
P932PMC publication ID5355658
P698PubMed publication ID27922666

P2093author name stringWei Wang
Yuan Wang
Qiong Wang
Yan Zheng
Yongping Shao
Jinjing Jia
Zhengxiao Li
Huling Yan
P2860cites workTwo human genes isolated by a novel method encode DNA-binding proteins containing a common region of homologyQ24294626
Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptorQ24306866
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
LL-37, the only human member of the cathelicidin family of antimicrobial peptidesQ28241675
Nuclear translocation of the Y-box binding protein by ultraviolet irradiationQ28257567
Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cellsQ28535383
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.Q30486489
Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells.Q30490685
Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancerQ33792003
Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications.Q34091593
NF-κB, an active player in human cancersQ34138728
LL‐37 as a therapeutic target for late stage prostate cancerQ34511108
Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitroQ34592889
Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials.Q35603108
Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapyQ36458742
YB-1, the E2F pathway, and regulation of tumor cell growthQ36755479
Human antimicrobial protein hCAP18/LL-37 promotes a metastatic phenotype in breast cancerQ37205544
Tumors sound the alarmin(s).Q37243109
Cathelicidin LL-37: a multitask antimicrobial peptideQ37668182
Y-box-binding protein 1 (YB-1) and its functionsQ37984603
YB-1: oncoprotein, prognostic marker and therapeutic target?Q38065264
Y-box binding protein 1--a prognostic marker and target in tumour therapyQ38181719
Cantharidin impairs cell migration and invasion of A375.S2 human melanoma cells by suppressing MMP-2 and -9 through PI3K/NF-κB signaling pathwaysQ38911160
The antimicrobial peptide human cationic antimicrobial protein-18/cathelicidin LL-37 as a putative growth factor for malignant melanoma.Q39639712
P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance.Q39701578
LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathwayQ39838058
Host defence peptide LL-37 induces IL-6 expression in human bronchial epithelial cells by activation of the NF-kappaB signaling pathway.Q39900346
The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y-box-binding protein-1 overexpressing tumor cellsQ40007855
Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasionQ40062395
The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cellsQ40086400
Overexpression of coxsackie and adenovirus receptor inhibit growth of human bladder cancer cell in vitro and in vivoQ40132212
The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance.Q40176953
Antimicrobial protein hCAP18/LL-37 is highly expressed in breast cancer and is a putative growth factor for epithelial cells.Q40479004
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.Q40609292
The up-regulation of Y-box binding proteins (DNA binding protein A and Y-box binding protein-1) as prognostic markers of hepatocellular carcinomaQ44919330
Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cellsQ45405723
Recent trends of cutaneous leishmaniasis in Alert Hospital, Addis AbabaQ46910496
Y-box binding protein-1 is a novel molecular target for tumor vesselsQ48234561
Twist promotes tumor cell growth through YB-1 expression.Q53507465
Molecular events in melanoma development and progressionQ77309976
Prognostic implications of the nuclear localization of Y-box-binding protein-1 and CXCR4 expression in ovarian cancer: their correlation with activated Akt, LRP/MVP and P-glycoprotein expressionQ80216629
The over expression of cathelicidin peptide LL37 in head and neck squamous cell carcinoma: the peptide marker for the prognosis of cancerQ84312777
P433issue1
P921main subjectcell migrationQ189092
antimicrobial peptideQ1201508
P304page(s)240-248
P577publication date2016-12-02
P1433published inMolecular Medicine ReportsQ26842180
P1476titleAntimicrobial peptide LL-37 promotes YB-1 expression, and the viability, migration and invasion of malignant melanoma cells
P478volume15

Reverse relations

cites work (P2860)
Q89326760Detection of a MicroRNA molecular signature of ultraviolet radiation in the superficial regions of melanocytic nevi on sun-exposed skin
Q91782691Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Q64277502Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling
Q54977356miR372 Promotes Progression of Liver Cancer Cells by Upregulating erbB-2 through Enhancement of YB-1.

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