Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway

scientific article published on 20 August 2012

Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1041946288
P356DOI10.1038/APS.2012.83
P932PMC publication ID4002710
P698PubMed publication ID22902986
P5875ResearchGate publication ID230697907

P2093author name stringYing Xue
Jian-Ming Hou
Qing-Ming Lin
P2860cites workLactoferrin is a potent regulator of bone cell activity and increases bone formation in vivoQ24294453
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
RANK is essential for osteoclast and lymph node developmentQ24598872
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Runx2: a master organizer of gene transcription in developing and maturing osteoblastsQ28274182
Milk ribonuclease-enriched lactoferrin induces positive effects on bone turnover markers in postmenopausal womenQ28307740
The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cellsQ28580727
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Osteoclast differentiation and activationQ29547556
Lactoferrin--a novel bone growth factorQ33218791
Relationship of bone turnover to bone density and fracturesQ34430413
Multifunctional roles of lactoferrin: a critical overviewQ34464216
OsteoimmunologyQ36693328
Transcription factors controlling osteoblastogenesisQ37106754
Twenty-five years of research on bovine lactoferrin applicationsQ37201798
Current and emerging therapies for osteoporosis.Q37613807
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilizationQ40327271
Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosisQ40565765
Lactoferrin: molecular structure and biological functionQ40926159
Defective bone remodelling in osteoprotegerin-deficient miceQ44751176
Oral bovine lactoferrin improves bone status of ovariectomized mice.Q51646877
Orally administered lactoferrin preserves bone mass and microarchitecture in ovariectomized rats.Q51648275
Effect of lactoferrin-embedded collagen membrane on osteogenic differentiation of human osteoblast-like cells.Q51821276
Human lactotransferrin: amino acid sequence and structural comparisons with other transferrinsQ70710358
The effect of ovariectomy on bone metabolism in ratsQ70947099
Lactoferrin reduces in vitro osteoclast differentiation and resorbing activityQ74577370
Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathwayQ83226947
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmicrostructureQ1498213
P304page(s)1277-1284
P577publication date2012-08-20
P1433published inActa Pharmacologica SinicaQ15749885
P1476titleBovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway
P478volume33

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Q38643354Alendronate Functionalized Mesoporous Bioactive Glass Nanospheres.
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Q35689317Bone Regeneration Is Promoted by Orally Administered Bovine Lactoferrin in a Rabbit Tibial Distraction Osteogenesis Model
Q37653861Clinical Impact and Cellular Mechanisms of Iron Overload-Associated Bone Loss
Q35684335Coupling Hydroxyapatite Nanocrystals with Lactoferrin as a Promising Strategy to Fine Regulate Bone Homeostasis
Q33582576Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines
Q38412968Effects of in ovo injection of bovine lactoferrin before incubation in layer breeder eggs on tibia measurements and performance of laying hens
Q96231641Hepcidin deficiency causes bone loss through interfering with the canonical Wnt/β-catenin pathway via Forkhead box O3a
Q57812844Influence of Iron on Bone Homeostasis
Q35935497Lactoferrin Induces Osteoblast Growth through IGF-1R.
Q46256576Lactoferrin in a Context of Inflammation-Induced Pathology
Q36745179Lactoferrin inhibits apoptosis through insulin-like growth factor I in primary rat osteoblasts
Q56516677Lactoferrin promote primary rat osteoblast proliferation and differentiation via up-regulation of insulin-like growth factor-1 expression
Q50135768Local application of lactoferrin promotes bone regeneration in a rat critical-sized calvarial defect model as demonstrated by micro-CT and histological analysis.
Q28551480Multi-Scale Agent-Based Multiple Myeloma Cancer Modeling and the Related Study of the Balance between Osteoclasts and Osteoblasts
Q33794181The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways

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