Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells

scientific article published on 12 January 2017

Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/CDDIS.2016.488
P932PMC publication ID5386388
P698PubMed publication ID28079882

P50authorHyun Seung BanQ59707837
P2093author name stringJoo-Young Im
Young-Jin Jung
Bo-Kyung Kim
Misun Won
Kyoung-Jae Won
Kyeong Eun Jung
P2860cites workRhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cellsQ24318183
Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligaseQ24320293
CHIP has a protective role against oxidative stress-induced cell death through specific regulation of endonuclease GQ28292712
STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagyQ28568829
noxin, a novel stress-induced gene involved in cell cycle and apoptosisQ28594946
Ubiquitin ligase CHIP suppresses cancer stem cell properties in a population of breast cancer cells.Q51508400
The stability of wild-type and deletion mutants of human C-terminus Hsp70-interacting protein (CHIP).Q51539506
CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.Q51574887
CHIPping away at base excision repair.Q51574893
DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion.Q51643074
Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathwayQ28910332
Identification of residues on Hsp70 and Hsp90 ubiquitinated by the cochaperone CHIPQ34048681
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase βQ34581562
Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinomaQ35043581
Balance between folding and degradation for Hsp90-dependent client proteins: a key role for CHIP.Q35121021
Decreased expression of CHIP leads to increased angiogenesis via VEGF-VEGFR2 pathway and poor prognosis in human renal cell carcinomaQ35663710
The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradationQ35939892
CHIP activates HSF1 and confers protection against apoptosis and cellular stressQ36266926
A CHIPotle in physiology and disease.Q38275347
Human Noxin is an anti-apoptotic protein in response to DNA damage of A549 non-small cell lung carcinomaQ38311315
The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5.Q38812367
DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancerQ38825679
ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-cateninQ38902925
p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosisQ39014692
MIF4G domain containing protein regulates cell cycle and hepatic carcinogenesis by antagonizing CDK2-dependent p27 stability.Q39043607
The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.Q39356833
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancerQ39358562
Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cellsQ40279515
Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.Q41271701
NOXIN as a cofactor of DNA polymerase-primase complex could promote hepatocellular carcinoma.Q41542420
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectlung cancerQ47912
P304page(s)e2554
P577publication date2017-01-12
P1433published inCell Death and DiseaseQ2197222
P1476titleStability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells
P478volume8

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cites work (P2860)
Q49798105Benzidine Induces Epithelial-Mesenchymal Transition of Human Bladder Cancer Cells through Activation of ERK5 Pathway
Q89558432CHIP-mediated ubiquitination of Galectin-1 predicts colorectal cancer prognosis
Q47101736CHIPped balance of proteostasis and longevity
Q92406835DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells
Q47291846DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.
Q93159937Development and validation of a CIMP-associated prognostic model for hepatocellular carcinoma
Q90122397Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner
Q39428376Hsp70 - a master regulator in protein degradation
Q92864486Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation