Herpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes

scientific article published on May 2010

Herpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1070985852
P356DOI10.3109/13550281003739040
P698PubMed publication ID20450378

P2093author name stringIsamu Mori
P2860cites workPrevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, IV, VI, VII, and XII.Q44749534
Reactivation of HSV-1 in the brain of patients with familial Alzheimer's diseaseQ44955143
Herpes simplex virus type 1 and Alzheimer's disease: the autophagy connection.Q45396897
Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulationQ45399423
The latency-associated transcript of herpes simplex virus type 1 promotes survival and stimulates axonal regeneration in sympathetic and trigeminal neuronsQ45404813
PKR-dependent autophagic degradation of herpes simplex virus type 1.Q45413954
Productive herpes simplex virus in brain of elderly normal subjects and Alzheimer's disease patientsQ45534759
Expression from the herpes simplex virus type 1 latency-associated promoter in the murine central nervous systemQ45744427
Herpes simplex virus type 1 gene expression and reactivation of latent infection in the central nervous systemQ45782777
Latency of alpha-herpes viruses is accompanied by a chronic inflammation in human trigeminal ganglia but not in dorsal root ganglia.Q54577994
Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaquesQ22252858
The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domainQ24292276
The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genesQ24607496
Herpes simplex virus type 1 latency in the murine nervous system is associated with oxidative damage to neuronsQ28140454
Herpes simplex virus type 1 in brain and risk of Alzheimer's diseaseQ28302548
Mild forms of herpes encephalitisQ33620497
Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing?Q33716707
The locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice.Q33780491
Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice.Q33894781
Herpes simplex virus type 1 in Alzheimer's disease: the enemy withinQ34011777
Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.Q34341979
Herpes simplex virus type 1 evades the effects of antibody and complement in vivoQ34345831
Basic principles of immunological surveillance of the normal central nervous systemQ34398602
The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteinsQ34479586
Synaptic retrogenesis and amyloid-beta in Alzheimer's diseaseQ34926455
Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effectsQ35020024
Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosisQ35320264
Herpes simplex virus gene products: the accessories reflect her lifestyle wellQ35625938
Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAPQ35899978
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-Q35964369
HSV ICP0 recruits USP7 to modulate TLR-mediated innate responseQ36105979
Olfactory transmission of neurotropic virusesQ36203757
Accessory genes define the relationship between the herpes simplex virus and its hostQ36543418
Anterograde spread of herpes simplex virus type 1 requires glycoprotein E and glycoprotein I but not Us9.Q37333821
Two small RNAs encoded within the first 1.5 kilobases of the herpes simplex virus type 1 latency-associated transcript can inhibit productive infection and cooperate to inhibit apoptosisQ37333965
Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal gangliaQ37365331
Interaction of ICP34.5 with Beclin 1 modulates herpes simplex virus type 1 pathogenesis through control of CD4+ T-cell responsesQ37452021
Herpes simplex virus type 1 latency-associated transcript inhibits apoptosis and promotes neurite sprouting in neuroblastoma cells following serum starvation by maintaining protein kinase B (AKT) levelsQ39768142
Herpes simplex virus type 1 glycoprotein E mediates retrograde spread from epithelial cells to neuritesQ39874187
Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1.Q39883251
Herpes simplex virus type 1 Us3 gene deletion influences toll-like receptor responses in cultured monocytic cellsQ39913603
Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products.Q39959993
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy proteinQ40051258
CTL are inactivated by herpes simplex virus-infected cells expressing a viral protein kinaseQ40609272
Stimulation of enveloped virus infection by beta-amyloid fibrilsQ40718080
Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptideQ41737202
Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latencyQ43130211
HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.Q43743343
The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B.Q44559466
P433issue3
P921main subjectHerpes simplex virus type 1Q655331
P304page(s)203-207
P577publication date2010-05-01
P1433published inJournal of NeuroVirologyQ6295640
P1476titleHerpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes
P478volume16

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cites work (P2860)
Q38003697Geriatric dermatoses: a clinical review of skin diseases in an aging population.
Q64100321Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders
Q40054408Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase
Q38001036Herpes simplex virus US3 protein kinase regulates host responses and determines neurovirulence

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