review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.2217/IMT.10.31 |
P698 | PubMed publication ID | 20636004 |
P50 | author | Jan L Ceuppens | Q45773073 |
P2093 | author name string | Stefaan W Van Gool | |
Bert Verbinnen | |||
P2860 | cites work | Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse | Q24290693 |
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Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? | Q28207052 | ||
The B7 family revisited | Q28240070 | ||
The inhibitory cytokine IL-35 contributes to regulatory T-cell function | Q28258462 | ||
Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade | Q28564305 | ||
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7 | Q28591451 | ||
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism | Q29614266 | ||
Regulatory T cells and immune tolerance | Q29616864 | ||
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy | Q29619109 | ||
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 | Q29619324 | ||
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis | Q29619339 | ||
CTLA-4 control over Foxp3+ regulatory T cell function | Q29619413 | ||
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells | Q30080038 | ||
The impact of T cell intrinsic antigen adaptation on peripheral immune tolerance | Q33260750 | ||
Mechanisms of tolerance induction: blockade of co-stimulation. | Q33772256 | ||
Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation | Q33814943 | ||
Mixed chimerism and transplantation tolerance | Q34131999 | ||
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion | Q42941965 | ||
T cell apoptosis by tryptophan catabolism | Q44137068 | ||
CTLA-4-Ig regulates tryptophan catabolism in vivo. | Q44170968 | ||
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo | Q44355387 | ||
Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys | Q44493665 | ||
OX40 controls islet allograft tolerance in CD154 deficient mice by regulating FOXP3+ Tregs | Q44892329 | ||
Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells | Q44986020 | ||
Beneficial effects of costimulatory blockade with anti-inducible costimulator antibody in conjunction with CTLA4Ig on prevention of islet xenograft rejection from rat to mouse | Q45183367 | ||
Costimulation blockade with belatacept in renal transplantation | Q46569880 | ||
Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity. | Q47725914 | ||
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. | Q51541351 | ||
Induction of regulatory cells and control of cellular but not vascular rejection by costimulation blockade in hamster-to-rat heart xenotransplantation. | Q51800713 | ||
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation. | Q51815669 | ||
OX40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival. | Q51823618 | ||
ICOS-Dependent and -independent functions of memory CD4 T cells in allograft rejection. | Q51966823 | ||
Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection. | Q51992235 | ||
Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockade. | Q53467808 | ||
CTLA-4 engagement and regulatory CD4+CD25+ T cells independently control CD8+-mediated responses under costimulation blockade. | Q53626991 | ||
Critical role of OX40 in CD28 and CD154-independent rejection. | Q53905524 | ||
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. | Q54073234 | ||
The role of B7 ligands (CD80 and CD86) in CD152-mediated allograft tolerance: a crosscheck hypothesis | Q56903575 | ||
When ligand becomes receptor--tolerance via B7 signaling on DCs | Q56904184 | ||
Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment | Q56906119 | ||
Blocking CD40 - CD154 and CD80/CD86 - CD28 interactions during primary allogeneic stimulation results in T cell anergy and high IL-10 production | Q56906817 | ||
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways | Q56908985 | ||
T cell tolerance by clonal elimination in the thymus | Q56922465 | ||
Pretransplant Donor Peripheral Blood Mononuclear Cells Infusion Induces Transplantation Tolerance by Generating Regulatory T Cells | Q57702909 | ||
Positive and negative selection of T cells | Q34157557 | ||
CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase | Q34356219 | ||
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates | Q34433847 | ||
CTLA-4 (CD152) and its involvement in autoimmune disease | Q34560446 | ||
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. | Q34569888 | ||
The B7-CD28 superfamily | Q34575331 | ||
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses | Q34650346 | ||
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation | Q34674495 | ||
OX40 ligand shuts down IL-10-producing regulatory T cells | Q35016533 | ||
T cell anergy | Q35019694 | ||
Specialization in tolerance: innate CD(4+)CD(25+) versus acquired TR1 and TH3 regulatory T cells | Q35630644 | ||
Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning | Q35679173 | ||
Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients | Q35824531 | ||
Regulatory T cells and mechanisms of immune system control | Q35852343 | ||
Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection | Q35939463 | ||
OX40 costimulation turns off Foxp3+ Tregs. | Q36007580 | ||
Peripheral tolerance of CD8 T lymphocytes | Q36076297 | ||
Regulation of immune and autoimmune responses by ICOS-B7h interaction | Q36115747 | ||
Regulation of immunity by self-reactive T cells | Q36148406 | ||
CTLA-4 is a second receptor for the B cell activation antigen B7 | Q36230356 | ||
Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance | Q36364608 | ||
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. | Q36370315 | ||
Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance | Q36401145 | ||
The induction and maintenance of T cell anergy | Q36438018 | ||
Regulation of the T cell response | Q36643790 | ||
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation | Q37088900 | ||
CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance | Q37106789 | ||
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. | Q37256978 | ||
TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade. | Q37290406 | ||
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo | Q37308435 | ||
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. | Q37382702 | ||
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. | Q39785791 | ||
Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. | Q40459668 | ||
CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. | Q40658295 | ||
T-cell-receptor affinity and thymocyte positive selection | Q41192128 | ||
The CD40 pathway in allograft rejection, acceptance, and tolerance | Q41642375 | ||
Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand | Q42767299 | ||
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin | Q42936502 | ||
P433 | issue | 4 | |
P304 | page(s) | 497-509 | |
P577 | publication date | 2010-07-01 | |
P1433 | published in | Immunotherapy | Q18713038 |
P1476 | title | Blocking costimulatory pathways: prospects for inducing transplantation tolerance | |
P478 | volume | 2 |