G protein-coupled receptor heteromers as new targets for drug development

scientific article published on January 2010

G protein-coupled receptor heteromers as new targets for drug development is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S1877-1173(10)91002-8
P698PubMed publication ID20691958
P5875ResearchGate publication ID45536577

P50authorRafael FrancoQ40238726
Enric I. CanelaQ52339029
Antoni CortésQ111519448
P2093author name stringCarme Lluís
Gemma Navarro
Josefa Mallol
Vicent Casadó
Sergi Ferré
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Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand seriesQ34244966
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Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4.Q36949065
Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.Q36970776
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Blocking striatal adenosine A2A receptors: a new strategy for basal ganglia disordersQ37067424
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayerQ37118269
The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intakeQ37376376
A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesiaQ37416417
Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.Q37446783
GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?Q37576200
Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cellsQ37587515
Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerizationQ37629365
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Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.Q39817865
Analysis of receptor oligomerization by FRAP microscopy.Q39880976
Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signalingQ40025475
Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-proteinQ40367280
The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinitiesQ40411565
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptorsQ40516448
Dopamine D2 and adenosine A2A receptors regulate NMDA-mediated excitation in accumbens neurons through A2A-D2 receptor heteromerizationQ41130757
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Oligomerization of mu- and delta-opioid receptors. Generation of novel functional propertiesQ44331872
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Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.Q55035681
P921main subjectG protein-coupled receptorQ38173
P304page(s)41-52
P577publication date2010-01-01
P1433published inProgress in Molecular Biology and Translational ScienceQ15753415
P1476titleG protein-coupled receptor heteromers as new targets for drug development
P478volume91

Reverse relations

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