Glycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease.

scientific article published on January 2010

Glycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2174/138161210793176581
P698PubMed publication ID20698823

P50authorJesús Ávila de GradoQ5930854
Miguel MedinaQ37835217
P2093author name stringMiguel Medina
Jesús Avila
P433issue25
P921main subjectAlzheimer's diseaseQ11081
P304page(s)2790-2798
P577publication date2010-01-01
P1433published inCurrent Pharmaceutical DesignQ5195068
P1476titleGlycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease
P478volume16

Reverse relations

cites work (P2860)
Q35018692A GSK-3β inhibitor protects against radiation necrosis in mouse brain
Q38258171A colorful history: the evolution of indigoids.
Q30458968Activation of GABA(B) receptors inhibits protein kinase B/glycogen synthase kinase 3 signaling
Q37728532Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells
Q38592451Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity
Q27315944Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling
Q42135408Deconstructing GSK-3: The Fine Regulation of Its Activity
Q38778638Defeating Alzheimer's disease and other dementias: a priority for European science and society
Q38230391Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer's disease
Q34071884Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.
Q49333511Disparate Effects of Lithium and a GSK-3 Inhibitor on Neuronal Oscillatory Activity in Prefrontal Cortex and Hippocampus
Q24610904Evidence for irreversible inhibition of glycogen synthase kinase-3β by tideglusib
Q38306065Further understanding of tau phosphorylation: implications for therapy.
Q35972878Future Therapeutics in Alzheimer's Disease: Development Status of BACE Inhibitors.
Q38673149GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory
Q21285144GSK-3β: A Bifunctional Role in Cell Death Pathways
Q48005072Gender difference in valproic acid-induced neuroprotective effects on APP/PS1 double transgenic mice modeling Alzheimer's disease
Q39728463Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment
Q38272835Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases
Q36335972Glycogen synthase kinase-3β regulates tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis via the NF-κB pathway in hepatocellular carcinoma
Q42759595Inhibition of glycogen synthase kinase-3 increases the cytotoxicity of enzastaurin
Q48311391Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance
Q38773662Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model
Q37946881Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies
Q37978196New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.
Q38149943New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease.
Q51533923Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.
Q26858851Platelet biomarkers in Alzheimer's disease
Q39393192Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates
Q26859305Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?
Q37256805Tau oligomers as potential targets for Alzheimer's diagnosis and novel drugs
Q41985456Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
Q38101982Understanding the relationship between GSK-3 and Alzheimer's disease: a focus on how GSK-3 can modulate synaptic plasticity processes
Q50707979Valproic Acid Modifies Synaptic Structure and Accelerates Neurite Outgrowth Via the Glycogen Synthase Kinase-3β Signaling Pathway in an Alzheimer's Disease Model.
Q38034060What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer's disease, about the therapeutic strategies in Alzheimer's research