scholarly article | Q13442814 |
P50 | author | Rakesh P. Patel | Q42121105 |
P2093 | author name string | Neil Hogg | |
Daniel B Kim-Shapiro | |||
P2860 | cites work | Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation | Q79243073 |
Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration | Q79758204 | ||
Nitrite reductase function of deoxymyoglobin: oxygen sensor and regulator of cardiac energetics and function | Q80314214 | ||
In vitro and in vivo kinetic handling of nitrite in blood: effects of varying hemoglobin oxygen saturation | Q80357971 | ||
Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator | Q80552011 | ||
Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays | Q80980901 | ||
Mechanisms of vasodilatation induced by nitrite instillation in intestinal lumen: possible role of hemoglobin | Q81391538 | ||
The emerging biology of the nitrite anion | Q82242034 | ||
Plasma nitroso compounds are decreased in patients with endothelial dysfunction | Q82468170 | ||
Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes | Q83039149 | ||
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite | Q24628398 | ||
Erythrocytes: oxygen sensors and modulators of vascular tone | Q24653317 | ||
The nitrite anion binds to human hemoglobin via the uncommon O-nitrito mode | Q27651209 | ||
Mechanism of NO-induced oxidation of myoglobin and hemoglobin | Q27733120 | ||
Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling | Q27939786 | ||
Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery | Q28344146 | ||
Exercising skeletal muscle blood flow in humans responds to reduction in arterial oxyhaemoglobin, but not to altered free oxygen | Q28351698 | ||
Nitrite reductase activity of cytochrome c | Q28386250 | ||
Protein S-nitrosylation: purview and parameters | Q29615181 | ||
Plasma nitrite response and arterial reactivity differentiate vascular health and performance | Q30436021 | ||
Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite | Q33553326 | ||
Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner | Q33590497 | ||
Nitric oxide and iron proteins | Q33631329 | ||
Reactions of nitrite in erythrocyte suspensions measured by membrane inlet mass spectrometry | Q33638871 | ||
Nitrate and nitrite in biology, nutrition and therapeutics | Q33685139 | ||
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver | Q33743659 | ||
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control | Q33901706 | ||
Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation. | Q33946476 | ||
Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action | Q33948130 | ||
Biological chemistry and clinical potential of S-nitrosothiols | Q33991767 | ||
Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the beta subunits | Q34469860 | ||
An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate | Q34694150 | ||
The functional nitrite reductase activity of the heme-globins | Q34791443 | ||
The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies. | Q34880703 | ||
Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans | Q35304987 | ||
Nitrite enhances RBC hypoxic ATP synthesis and the release of ATP into the vasculature: a new mechanism for nitrite-induced vasodilation | Q35547955 | ||
Erythrocytes are the major intravascular storage sites of nitrite in human blood. | Q35847971 | ||
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation | Q35849284 | ||
Artery-to-vein differences in nitric oxide metabolites are diminished in sepsis | Q35878275 | ||
Mechanistic studies of S-nitrosothiol formation by NO*/O2 and by NO*/methemoglobin | Q46409853 | ||
Rates of nitric oxide dissociation from hemoglobin | Q46554493 | ||
Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals | Q46713563 | ||
Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin | Q46914805 | ||
Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation | Q46983570 | ||
Nitrite-methemoglobin inadequate for hypoxic vasodilation | Q47782092 | ||
Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin | Q47842687 | ||
Comparative analysis of nitrite uptake and hemoglobin-nitrite reactions in erythrocytes: sorting out uptake mechanisms and oxygenation dependencies. | Q50586090 | ||
Enhancing nitrite reductase activity of modified hemoglobin: bis-tetramers and their PEGylated derivatives. | Q50593506 | ||
NO metabolite flux across the human coronary circulation. | Q50694341 | ||
S-nitrosohemoglobin: a mechanism for its formation in conjunction with nitrite reduction by deoxyhemoglobin. | Q50739637 | ||
The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. | Q51498689 | ||
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. | Q51556849 | ||
Role of nitric oxide in capillary perfusion and oxygen delivery regulation during systemic hypoxia. | Q51820412 | ||
Rate of oxygen loss from arterioles is an order of magnitude higher than expected. | Q52537455 | ||
Blood vessel specific vaso-activity to nitrite under normoxic and hypoxic conditions. | Q53516185 | ||
Effects of dietary nitrate on blood pressure in healthy volunteers. | Q55042872 | ||
Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans | Q56864000 | ||
Reply to 'Nitrite–methemoglobin inadequate for hypoxic vasodilation' | Q58205629 | ||
Stomach NO synthesis | Q59048359 | ||
[38] Stopped-flow, rapid mixing measurements of ligand binding to hemoglobin and red cells | Q59599949 | ||
Hypoxic Modulation of Exogenous Nitrite-Induced Vasodilation in Humans | Q60056639 | ||
Nitrite-dependent vasodilation is facilitated by hypoxia and is independent of known NO-generating nitrite reductase activities | Q63413250 | ||
Cooperativity in the dissociation of nitric oxide from hemoglobin | Q67771608 | ||
Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites | Q70976030 | ||
The erythrocyte as a regulator of vascular tone | Q70986072 | ||
ATP: the red blood cell link to NO and local control of the pulmonary circulation | Q71978359 | ||
Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs | Q73184291 | ||
Active nitric oxide produced in the red cell under hypoxic conditions by deoxyhemoglobin-mediated nitrite reduction | Q73894738 | ||
Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions | Q74601251 | ||
Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin | Q36040992 | ||
Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide: mechanism(s) and physiologic versus pathophysiologic relevance | Q36075181 | ||
Assessments of the chemistry and vasodilatory activity of nitrite with hemoglobin under physiologically relevant conditions | Q36089728 | ||
Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis | Q36676815 | ||
The reaction between nitrite and oxyhemoglobin: a mechanistic study | Q36741493 | ||
Nitric oxide synthase-derived plasma nitrite predicts exercise capacity | Q36767764 | ||
Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall | Q36844531 | ||
Red not dead: signaling in and from erythrocytes | Q36981005 | ||
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics | Q37048314 | ||
Nitrite-induced improved blood circulation associated with an increase in a pool of RBC-NO with no bioactivity | Q37148270 | ||
Quantification of intermediates formed during the reduction of nitrite by deoxyhemoglobin | Q37176397 | ||
Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation | Q37200270 | ||
Magnetic resonance study of the transmembrane nitrite diffusion | Q37258856 | ||
The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase | Q37265485 | ||
Nitrite as regulator of hypoxic signaling in mammalian physiology | Q37301113 | ||
Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage | Q37535175 | ||
An electron paramagnetic resonance study of the affinity of nitrite for methemoglobin | Q37628879 | ||
A mechanism for the conversion of oxyhemoglobin to methemoglobin by nitrite | Q39125785 | ||
Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase | Q39599563 | ||
Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase. | Q39691316 | ||
Reactions of nitrite with hemoglobin measured by membrane inlet mass spectrometry | Q39890157 | ||
Hemoglobin mediated nitrite activation of soluble guanylyl cyclase. | Q40413442 | ||
Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction | Q41873130 | ||
Nitric oxide red blood cell membrane permeability at high and low oxygen tension | Q42075022 | ||
Bound NO in human red blood cells: fact or artifact? | Q42465303 | ||
Stable-isotope dilution GC-MS approach for nitrite quantification in human whole blood, erythrocytes, and plasma using pentafluorobenzyl bromide derivatization: nitrite distribution in human blood. | Q42472785 | ||
Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues | Q42489219 | ||
Endothelial nitric oxide synthase reduces nitrite anions to NO under anoxia. | Q42490052 | ||
Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways | Q42589045 | ||
Intragastric nitric oxide production in humans: measurements in expelled air. | Q42876376 | ||
Nitrite and nitroglycerin induce rapid release of the vasodilator ATP from erythrocytes: Relevance to the chemical physiology of local vasodilation | Q43194303 | ||
Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise | Q43242337 | ||
Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation | Q43263730 | ||
Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations | Q44529586 | ||
Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation | Q44758431 | ||
Oxygen exchange in the microcirculation of hamster retractor muscle | Q45072508 | ||
Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. | Q45100928 | ||
Nitrite catalyzes ferriheme protein reductive nitrosylation | Q46116429 | ||
P433 | issue | 3 | |
P304 | page(s) | 507-515 | |
P577 | publication date | 2010-10-14 | |
P1433 | published in | Cardiovascular Research | Q4642329 |
P1476 | title | The potential role of the red blood cell in nitrite-dependent regulation of blood flow | |
P478 | volume | 89 |
Q50561507 | A mathematical model for the role of N2O3 in enhancing nitric oxide bioavailability following nitrite infusion. |
Q28390815 | Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy |
Q37204151 | Effects of erythrocyte aging on nitric oxide and nitrite metabolism |
Q35614475 | Effects of nitric oxide and its congeners on sickle red blood cell deformability |
Q38185035 | Endothelial nitric oxide synthase in red blood cells: key to a new erythrocrine function? |
Q48967987 | Hemoglobin Effects on Nitric Oxide Mediated Hypoxic Vasodilation. |
Q27022432 | Hemoglobin-mediated nitric oxide signaling |
Q34530182 | Inorganic nitrite and chronic tissue ischaemia: a novel therapeutic modality for peripheral vascular diseases. |
Q35552149 | Inorganic nitrite therapy: historical perspective and future directions. |
Q38136225 | Is methemoglobin an inert bystander, biomarker or a mediator of oxidative stress--The example of anemia? |
Q34958622 | Mechanisms of human erythrocytic bioactivation of nitrite |
Q28384653 | Mechanisms of nitrite bioactivation |
Q50514102 | Melatonin attenuates hypochlorous acid-mediated heme destruction, free iron release, and protein aggregation in hemoglobin. |
Q27336105 | Microfluidic device with tunable post arrays and integrated electrodes for studying cellular release |
Q38017819 | Nitric oxide formation versus scavenging: the red blood cell balancing act. |
Q37887771 | Nitric oxide: a guardian for vascular grafts? |
Q34603164 | Oxygen mediates vascular smooth muscle relaxation in hypoxia |
Q37695308 | Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest |
Q50507655 | Pyruvate effects on red blood cells during in vitro cardiopulmonary bypass with dogs' blood. |
Q34907759 | Red blood cell age and potentiation of transfusion-related pathology in trauma patients. |
Q42583230 | Review focus on inorganic nitrite and nitrate in cardiovascular health and disease. |
Q43050724 | Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation |
Q49346285 | The dichotomous role of H2S in cancer cell biology? Déjà vu all over again. |
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