scholarly article | Q13442814 |
P50 | author | Bert W. O'Malley | Q827492 |
P2093 | author name string | Brian York | |
P2860 | cites work | Cancer Research | Q326097 |
GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor | Q73788330 | ||
SRC-1 and TIF2 control energy balance between white and brown adipose tissues | Q78732732 | ||
Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness | Q83378216 | ||
A map of recent positive selection in the human genome | Q21563624 | ||
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase | Q24295084 | ||
Nuclear protein CBP is a coactivator for the transcription factor CREB | Q24319801 | ||
RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2 | Q24319818 | ||
TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1 | Q24321891 | ||
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300 | Q24324556 | ||
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors | Q24562254 | ||
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors | Q24600501 | ||
Biochemical method for inserting new genetic information into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli | Q24616050 | ||
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing | Q24646988 | ||
Distinct steady-state nuclear receptor coregulator complexes exist in vivo | Q24679780 | ||
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Q27651364 | ||
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha | Q27730245 | ||
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily | Q27860465 | ||
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase | Q28144544 | ||
Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation | Q28216959 | ||
Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu | Q28241103 | ||
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer | Q28245902 | ||
Steroid receptor coactivator-1 is a histone acetyltransferase | Q28248899 | ||
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription | Q28254487 | ||
Gene Regulation for Higher Cells: A Theory | Q28256064 | ||
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration | Q28273310 | ||
Primary structure and expression of a functional human glucocorticoid receptor cDNA | Q28282278 | ||
Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer | Q28287028 | ||
A transcriptional co-repressor that interacts with nuclear hormone receptors | Q28289864 | ||
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation | Q28303864 | ||
The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development | Q28509946 | ||
GAC63, a GRIP1-dependent nuclear receptor coactivator | Q28589886 | ||
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease | Q28592482 | ||
CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivators | Q28594257 | ||
A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia | Q28609835 | ||
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function | Q29547918 | ||
Integrative genomic profiling of human prostate cancer | Q29619905 | ||
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor | Q31168538 | ||
Acute mixed lineage leukemia with an inv(8)(p11q13) resulting in fusion of the genes for MOZ and TIF2. | Q32025732 | ||
Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases? | Q33634287 | ||
Streamlined analysis schema for high-throughput identification of endogenous protein complexes | Q33664691 | ||
The SRC family of nuclear receptor coactivators | Q33860695 | ||
Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities | Q33922863 | ||
Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. | Q33934565 | ||
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family | Q34013708 | ||
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer | Q34181456 | ||
Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites. | Q34235903 | ||
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors | Q34258611 | ||
Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid X receptor | Q34302232 | ||
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene | Q34460757 | ||
Nuclear receptor coregulators and human disease | Q34645711 | ||
Ovalbumin Messenger RNA of Chick Oviduct: Partial Characterization, Estrogen Dependence, and Translation In Vitro | Q34702664 | ||
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse | Q35071146 | ||
Nuclear receptor coactivator function in reproductive physiology and behavior. | Q35175574 | ||
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program | Q35215073 | ||
The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation | Q35641696 | ||
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover | Q35641931 | ||
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response | Q35781606 | ||
Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human | Q36238321 | ||
Studies on the mechanism of estrogen-mediated tissue differentiation: regulation of nuclear transcription and induction of new RNA species | Q36473319 | ||
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. | Q36540639 | ||
HATs off to PIC assembly | Q36594408 | ||
Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes | Q36601454 | ||
To die or not to die: a HAT trick | Q36692555 | ||
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene | Q36692660 | ||
Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator family? | Q36912703 | ||
Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation | Q36931106 | ||
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. | Q36964392 | ||
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover | Q37001705 | ||
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation | Q37068408 | ||
Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. | Q37253958 | ||
Identification of a negative regulatory function for steroid receptors | Q37287283 | ||
Multi-modulation of nuclear receptor coactivators through posttranslational modifications | Q37329666 | ||
Identification of a high affinity nuclear acceptor site for estrogen receptor of calf uterus | Q37436020 | ||
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation | Q38325898 | ||
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence | Q39874727 | ||
Purification of human uterine progesterone receptor | Q39919376 | ||
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock | Q40118969 | ||
Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter | Q40438634 | ||
Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity. | Q40604671 | ||
Preliminary crystallographic studies of the ligand-binding domain of the thyroid hormone receptor complexed with triiodothyronine | Q40724472 | ||
AIB1 enhances estrogen-dependent induction of cyclin D1 expression | Q40805226 | ||
Involvement of nuclear receptor coactivator SRC-1 in estrogen-dependent cell growth of MCF-7 cells | Q40908257 | ||
Polarity-specific activities of retinoic acid receptors determined by a co-repressor. | Q41284148 | ||
Enhancement of human estrogen receptor activity by SPT6: a potential coactivator | Q41393826 | ||
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice | Q42445725 | ||
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance | Q42490453 | ||
An isoform of the coactivator AIB1 that increases hormone and growth factor sensitivity is overexpressed in breast cancer. | Q43705564 | ||
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice | Q44620881 | ||
Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA | Q45799129 | ||
Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors | Q46160477 | ||
Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer | Q48506903 | ||
Reduction of Coactivator Expression by Antisense Oligodeoxynucleotides Inhibits ER Transcriptional Activity and MCF-7 Proliferation | Q56602212 | ||
Advances in male contraception | Q56679619 | ||
Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP | Q59095054 | ||
The ovalbumin gene. Partial purification of the coding strand | Q67738991 | ||
Converting a eukaryotic transcriptional inhibitor into an activator | Q67950223 | ||
Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element | Q69419613 | ||
Characterization of the purified activated glucocorticoid receptor from rat liver cytosol | Q71300738 | ||
P433 | issue | 50 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | systems biology | Q815297 |
P304 | page(s) | 38743-38750 | |
P577 | publication date | 2010-10-18 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Steroid receptor coactivator (SRC) family: masters of systems biology | |
Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology | |||
P478 | volume | 285 |
Q42026389 | "True" antiandrogens-selective non-ligand-binding pocket disruptors of androgen receptor-coactivator interactions: novel tools for prostate cancer |
Q55357800 | A New Role for Estrogen Receptor α in Cell Proliferation and Cancer: Activating the Anticipatory Unfolded Protein Response. |
Q37701748 | A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction |
Q28652931 | A role for Taiman in insect metamorphosis |
Q35949273 | Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy |
Q35034354 | Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. |
Q36176430 | Adipose tissue signaling by nuclear receptors in metabolic complications of obesity |
Q37713008 | Agonist-mediated assembly of the crustacean methyl farnesoate receptor |
Q37940570 | An unhealthy relationship: viral manipulation of the nuclear receptor superfamily |
Q35867933 | Androgen-induced activation of gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) transcription: essential role of a nonclassical androgen response element half-site |
Q38076345 | Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors. |
Q36492875 | Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations |
Q39144275 | Brain nuclear receptors and body weight regulation |
Q27022532 | Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials |
Q41991957 | Cellular proteome, coregulators, endocrine system and the human brain: the Regulatory biology of humanism |
Q28119116 | Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death |
Q44084395 | Critical components of the pluripotency network are targets for the p300/CBP interacting protein (p/CIP) in embryonic stem cells |
Q42716405 | Cutting SRC-1 down to size in endometriosis |
Q90556071 | Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element |
Q38622508 | Does corticosterone regulate the onset of breeding in free-living birds?: The CORT-Flexibility Hypothesis and six potential mechanisms for priming corticosteroid function. |
Q91792171 | ESR1 mutations: Pièce de résistance |
Q42811467 | Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60. |
Q39002337 | Effects of Sex Steroids in the Human Brain |
Q28538592 | Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis |
Q28083698 | Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited |
Q47656696 | Evolution of the androgen-induced male phenotype |
Q26752615 | Gene Expression Control by Glucocorticoid Receptors during Innate Immune Responses |
Q36797684 | General molecular biology and architecture of nuclear receptors |
Q36926842 | Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer |
Q47144286 | Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. |
Q34265010 | Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis |
Q30316789 | Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo |
Q48391527 | Hormonal regulation of steroid receptor coactivator-1 mRNA in the male and female green anole brain |
Q58572788 | Imbalanced expression pattern of steroid receptor coactivator-1 and -3 in liver cancer compared with normal liver: An immunohistochemical study with tissue microarray |
Q37099757 | Interaction of glucocorticoid receptor (GR) with estrogen receptor (ER) α and activator protein 1 (AP1) in dexamethasone-mediated interference of ERα activity |
Q38789346 | Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action. |
Q36419269 | Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction |
Q33580471 | LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells |
Q41108236 | Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. |
Q36262595 | Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). |
Q35033872 | Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin |
Q87698437 | MicroRNA-195 regulates steroid receptor coactivator-3 protein expression in hepatocellular carcinoma cells |
Q34530412 | Mining functional subgraphs from cancer protein-protein interaction networks |
Q26829103 | Minireview: Conversing with chromatin: the language of nuclear receptors |
Q36600139 | Modulation of testosterone-dependent male sexual behavior and the associated neuroplasticity. |
Q24305590 | Molecular mechanism of WW-domain binding protein-2 coactivation function in estrogen receptor signaling |
Q24293034 | Mutation in KANK2, encoding a sequestering protein for steroid receptor coactivators, causes keratoderma and woolly hair |
Q35082574 | Nuclear receptor coactivators: master regulators of human health and disease |
Q38110503 | Nuclear receptor control of enterohepatic circulation. |
Q37209671 | Nuclear receptors in inflammation control: repression by GR and beyond. |
Q35626357 | Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer. |
Q37577954 | Overexpression of SRC-3 promotes esophageal squamous cell carcinoma aggressiveness by enhancing cell growth and invasiveness |
Q90841147 | Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway |
Q38035237 | Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding |
Q49080367 | Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis. |
Q33701396 | Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex |
Q30429906 | Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences |
Q33821604 | Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay |
Q36932564 | Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family |
Q34130185 | Residual structures, conformational fluctuations, and electrostatic interactions in the synergistic folding of two intrinsically disordered proteins |
Q27683572 | Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network |
Q30408649 | Retinoic acid actions through mammalian nuclear receptors |
Q28512586 | Role of nuclear receptor coactivator 3 (Ncoa3) in pluripotency maintenance |
Q35128269 | Role of the nuclear receptor coactivator AIB1-Delta4 splice variant in the control of gene transcription |
Q35952104 | Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing |
Q36122756 | Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids. |
Q36300613 | SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer |
Q46266824 | Seasonal and sexual dimorphisms in expression of androgen receptor and its coactivators in brain and peripheral copulatory tissues of the green anole |
Q35854664 | Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction |
Q34575905 | Small molecule inhibitors as probes for estrogen and androgen receptor action |
Q41815633 | Small-molecule hormones: molecular mechanisms of action |
Q38848340 | Steroid Hormone Receptor Coregulators in Endocrine Cancers |
Q55220967 | Steroid Receptor Coactivator-Interacting Protein (SIP) Suppresses Myocardial Injury Caused by Acute Pancreatitis. |
Q39053714 | Steroid receptor co-activator-3 promotes osteosarcoma progression through up-regulation of FoxM1. |
Q35418815 | Steroid receptor coactivator 2 modulates steroid-dependent male sexual behavior and neuroplasticity in Japanese quail (Coturnix japonica). |
Q64120209 | Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis |
Q36808705 | Steroid receptor coactivator-3 as a potential molecular target for cancer therapy |
Q35456938 | Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy |
Q26825815 | Steroid receptor coactivators: servants and masters for control of systems metabolism |
Q38066022 | Steroid regulation of menstrual bleeding and endometrial repair |
Q35562822 | Structural dynamics, intrinsic disorder, and allostery in nuclear receptors as transcription factors |
Q39220247 | Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer cells |
Q33967993 | The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs |
Q38820069 | The Role of Steroid Receptor Coactivators in Hormone Dependent Cancers and Their Potential as Therapeutic Targets |
Q35828548 | The function of steroid receptor coactivator-1 in normal tissues and cancer |
Q35906989 | The multifaceted mineralocorticoid receptor |
Q37619321 | The nuclear coactivator amplified in breast cancer 1 maintains tumor-initiating cells during development of ductal carcinoma in situ |
Q39405288 | The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 ligase PIAS1. |
Q37153637 | The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis |
Q35099103 | Thyroid hormone receptor mutations in cancer and resistance to thyroid hormone: perspective and prognosis |
Q33565455 | Transcriptional Regulation of the Mitochondrial Citrate and Carnitine/Acylcarnitine Transporters: Two Genes Involved in Fatty Acid Biosynthesis and β-oxidation |
Q92765807 | Transcriptional and Epigenomic Regulation of Adipogenesis |
Q27030886 | Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology |
Q47448492 | Trichothecenes: immunomodulatory effects, mechanisms, and anti-cancer potential |
Q39445786 | WW domain-binding protein 2: an adaptor protein closely linked to the development of breast cancer |
Q36720498 | Yin Yang 1 promotes hepatic gluconeogenesis through upregulation of glucocorticoid receptor. |
Q39184999 | cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1 |
Q38998609 | microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta |
Q39152504 | p300, but not PCAF, collaborates with IRF-1 in stimulating TRIM22 expression independently of its histone acetyltransferase activity |