Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology

scientific article published on October 18, 2010

Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.R110.193367
P953full work available at URLhttp://www.jbc.org/article/S0021925820605725/pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20956538/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20956538/?tool=EBI
http://intl.jbc.org/cgi/content/abstract/285/50/38743
https://europepmc.org/articles/PMC2998129
https://europepmc.org/articles/PMC2998129?pdf=render
https://doi.org/10.1074/jbc.r110.193367
https://api.elsevier.com/content/article/PII:S0021925820605725?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820605725?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.R110.193367
P932PMC publication ID2998129
P698PubMed publication ID20956538
P5875ResearchGate publication ID47459505

P50authorBert W. O'MalleyQ827492
P2093author name stringBrian York
P2860cites workCancer ResearchQ326097
GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptorQ73788330
SRC-1 and TIF2 control energy balance between white and brown adipose tissuesQ78732732
Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasivenessQ83378216
A map of recent positive selection in the human genomeQ21563624
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinaseQ24295084
Nuclear protein CBP is a coactivator for the transcription factor CREBQ24319801
RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2Q24319818
TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1Q24321891
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300Q24324556
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptorsQ24562254
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptorsQ24600501
Biochemical method for inserting new genetic information into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coliQ24616050
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencingQ24646988
Distinct steady-state nuclear receptor coregulator complexes exist in vivoQ24679780
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNAQ27651364
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alphaQ27730245
Sequence and characterization of a coactivator for the steroid hormone receptor superfamilyQ27860465
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylaseQ28144544
Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferationQ28216959
Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/NeuQ28241103
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancerQ28245902
Steroid receptor coactivator-1 is a histone acetyltransferaseQ28248899
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcriptionQ28254487
Gene Regulation for Higher Cells: A TheoryQ28256064
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migrationQ28273310
Primary structure and expression of a functional human glucocorticoid receptor cDNAQ28282278
Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancerQ28287028
A transcriptional co-repressor that interacts with nuclear hormone receptorsQ28289864
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activationQ28303864
The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland developmentQ28509946
GAC63, a GRIP1-dependent nuclear receptor coactivatorQ28589886
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's diseaseQ28592482
CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivatorsQ28594257
A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemiaQ28609835
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor functionQ29547918
Integrative genomic profiling of human prostate cancerQ29619905
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptorQ31168538
Acute mixed lineage leukemia with an inv(8)(p11q13) resulting in fusion of the genes for MOZ and TIF2.Q32025732
Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases?Q33634287
Streamlined analysis schema for high-throughput identification of endogenous protein complexesQ33664691
The SRC family of nuclear receptor coactivatorsQ33860695
Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activitiesQ33922863
Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.Q33934565
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) familyQ34013708
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancerQ34181456
Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites.Q34235903
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factorsQ34258611
Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid X receptorQ34302232
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) geneQ34460757
Nuclear receptor coregulators and human diseaseQ34645711
Ovalbumin Messenger RNA of Chick Oviduct: Partial Characterization, Estrogen Dependence, and Translation In VitroQ34702664
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouseQ35071146
Nuclear receptor coactivator function in reproductive physiology and behavior.Q35175574
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic programQ35215073
The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylationQ35641696
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnoverQ35641931
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory responseQ35781606
Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the humanQ36238321
Studies on the mechanism of estrogen-mediated tissue differentiation: regulation of nuclear transcription and induction of new RNA speciesQ36473319
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.Q36540639
HATs off to PIC assemblyQ36594408
Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genesQ36601454
To die or not to die: a HAT trickQ36692555
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor geneQ36692660
Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator family?Q36912703
Nuclear receptor coregulators: judges, juries, and executioners of cellular regulationQ36931106
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.Q36964392
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnoverQ37001705
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formationQ37068408
Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2.Q37253958
Identification of a negative regulatory function for steroid receptorsQ37287283
Multi-modulation of nuclear receptor coactivators through posttranslational modificationsQ37329666
Identification of a high affinity nuclear acceptor site for estrogen receptor of calf uterusQ37436020
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activationQ38325898
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrenceQ39874727
Purification of human uterine progesterone receptorQ39919376
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clockQ40118969
Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoterQ40438634
Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity.Q40604671
Preliminary crystallographic studies of the ligand-binding domain of the thyroid hormone receptor complexed with triiodothyronineQ40724472
AIB1 enhances estrogen-dependent induction of cyclin D1 expressionQ40805226
Involvement of nuclear receptor coactivator SRC-1 in estrogen-dependent cell growth of MCF-7 cellsQ40908257
Polarity-specific activities of retinoic acid receptors determined by a co-repressor.Q41284148
Enhancement of human estrogen receptor activity by SPT6: a potential coactivatorQ41393826
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient miceQ42445725
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balanceQ42490453
An isoform of the coactivator AIB1 that increases hormone and growth factor sensitivity is overexpressed in breast cancer.Q43705564
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in miceQ44620881
Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNAQ45799129
Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptorsQ46160477
Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggererQ48506903
Reduction of Coactivator Expression by Antisense Oligodeoxynucleotides Inhibits ER Transcriptional Activity and MCF-7 ProliferationQ56602212
Advances in male contraceptionQ56679619
Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBPQ59095054
The ovalbumin gene. Partial purification of the coding strandQ67738991
Converting a eukaryotic transcriptional inhibitor into an activatorQ67950223
Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response elementQ69419613
Characterization of the purified activated glucocorticoid receptor from rat liver cytosolQ71300738
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectsystems biologyQ815297
P304page(s)38743-38750
P577publication date2010-10-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleSteroid receptor coactivator (SRC) family: masters of systems biology
Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology
P478volume285

Reverse relations

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