Immunohistochemical Surrogates for Genetic Alterations of CCDN1, PML, ALK, and NPM1 Genes in Lymphomas and Acute Myeloid Leukemia

scientific article published on October 29, 2010

Immunohistochemical Surrogates for Genetic Alterations of CCDN1, PML, ALK, and NPM1 Genes in Lymphomas and Acute Myeloid Leukemia is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.BEHA.2010.09.001
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S1521692610000629?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S1521692610000629?httpAccept=text/xml
P698PubMed publication ID21112040

P50authorBrunangelo FaliniQ30119395
Maria Paola MartelliQ88187052
Christian ThiedeQ42323747
Stefano A PileriQ86426885
P2093author name stringEnrico Tiacci
Stefano Ascani
P2860cites workALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)Q24336482
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Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growthQ28216536
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphomaQ28250347
Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3Q28253494
Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemiasQ28301353
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Major nucleolar proteins shuttle between nucleus and cytoplasmQ29620425
Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classificationQ33254865
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Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypesQ33699243
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasmsQ34099059
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Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistryQ34487204
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Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profilingQ35848185
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SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.Q37406791
Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt's lymphomaQ37406794
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How I treat mantle cell lymphoma.Q37531574
Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectivesQ37601266
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.Q40321232
Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosminQ40389129
An immunofluorescent assay for acute promyelocytic leukemia cellsQ41043170
Frequent expression of the NPM-ALK chimeric fusion protein in anaplastic large-cell lymphoma, lympho-histiocytic typeQ41953773
A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin, and ARF.Q42806442
Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutantsQ42826742
Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help.Q42832529
ALK expression defines a distinct group of T/null lymphomas ("ALK lymphomas") with a wide morphological spectrum.Q42850888
Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy.Q43103153
ALK-positive diffuse large B-cell lymphoma is associated with Clathrin-ALK rearrangements: report of 6 casesQ44451877
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibodyQ44913301
Immunofluorescent analysis with the anti-PML monoclonal antibody PG-M3 for rapid and accurate genetic diagnosis of acute promyelocytic leukemiaQ44996369
Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia.Q46156916
ALK-positive anaplastic large cell lymphoma mimicking nodular sclerosis Hodgkin's lymphoma: report of 10 cases.Q51822094
The rapid diagnosis of acute promyelocytic leukaemia using PML (5E10) monoclonal antibody.Q52867615
Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases.Q53561028
SP4, a novel anti-cyclin D1 rabbit monoclonal antibody, is a highly sensitive probe for identifying mantle cell lymphomas bearing the t(11;14)(q13;q32) translocation.Q53649725
In human genome, generation of a nuclear export signal through duplication appears unique to nucleophosmin (NPM1) mutations and is restricted to AML.Q54398146
The nucleolusQ57166314
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphomaQ57279573
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CD5-undetected by immunohistochemistry, t(11;14)(q13;q32)-positive conjunctival mantle cell lymphoma: a case reportQ57647013
Aberrant Bcl6 Protein Expression in Mantle Cell LymphomaQ58010967
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemiaQ58882378
A western blot assay for detecting mutant nucleophosmin (NPM1) proteins in acute myeloid leukaemiaQ60171386
Cytoplasmic mutated nucleophosmin (NPM) defines the molecular status of a significant fraction of myeloid sarcomasQ61637145
In-situ mantle cell lymphoma-a report of two casesQ63633967
Bone marrow involvement in anaplastic large cell lymphoma. Immunohistochemical detection of minimal disease and its prognostic significanceQ72400586
Lymphomas expressing ALK fusion protein(s) other than NPM-ALKQ73160429
A subset of CD5- diffuse large B-cell lymphomas expresses nuclear cyclin D1 with aberrations at the CCND1 locusQ80880100
Mantle cell lymphoma with aberrant expression of CD10Q81384010
Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): a comparison with NPMc+ AMLQ81600809
A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemiasQ84386374
Nuclear expression of sox11 is highly associated with mantle cell lymphoma but is independent of t(11;14)(q13;q32) in non-mantle cell B-cell neoplasmsQ84626091
Immunophenotypic variations in mantle cell lymphomaQ84761573
Mantle cell lymphomaQ84826641
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectimmunohistochemistryQ899285
P304page(s)417-431
P577publication date2010-09-01
2010-10-29
P1433published inBest Practice and Research: Clinical HaematologyQ15755888
P1476titleImmunohistochemical surrogates for genetic alterations of CCDN1, PML, ALK, and NPM1 genes in lymphomas and acute myeloid leukemia
Immunohistochemical Surrogates for Genetic Alterations of CCDN1, PML, ALK, and NPM1 Genes in Lymphomas and Acute Myeloid Leukemia
P478volume23

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Q84578015ERG gene rearrangement status in prostate cancer detected by immunohistochemistrycites workP2860

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