Review article: dexmedetomidine: does it have potential in palliative medicine?

scientific article published on 03 December 2010

Review article: dexmedetomidine: does it have potential in palliative medicine? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1177/1049909110389804
P8608Fatcat IDrelease_sflux2sfibgntmyci3d57nlqbi
P698PubMed publication ID21131636
P5875ResearchGate publication ID49658354

P2093author name stringEric Prommer
P2860cites workDelirium: optimising managementQ24524866
alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic roleQ28142296
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effectsQ28205334
Pharmacology of sedative-analgesic agents: dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonistsQ28250766
Dexmedetomidine infusion for more than 24 hours in critically ill patients: sedative and cardiovascular effectsQ28279789
Dexmedetomidine in anaesthesiaQ28301772
Human brain imidazoline receptors: further characterization with [3H]clonidineQ48207505
Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca2+ elevation in cultured rat dorsal root ganglia cellsQ48591454
The use of dexmedetomidine in pediatric cardiac surgeryQ48689528
Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker; a cautionary tale.Q50925247
Pharmacokinetics and pharmacodynamics of transdermal dexmedetomidine.Q51646185
The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized ratQ51692496
Spinal Antinociception by Dexmedetomidine, a Highly Selective α2-Adrenergic AgonistQ51717737
Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions.Q52028622
Diagnosis and management of delirium near the end of lifeQ34297691
New agents for sedation in the intensive care unitQ34474040
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice.Q35048705
Delirium in advanced cancer patientsQ35805731
Dexmedetomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patientsQ36108269
The use of dexmedetomidine to facilitate acute discontinuation of opioids after cardiac transplantation in children.Q36251652
Effect of alpha1-adrenergic receptors in cardiac pathophysiologyQ36636928
Dexmedetomidine: an updated reviewQ36735205
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphineQ37002353
A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patients.Q37050222
Dexmedetomidine: a review of clinical applicationsQ37228095
Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trialQ37279801
Palliating delirium in patients with cancerQ37382797
Treating agitation with dexmedetomidine in the ICU.Q37456032
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trialQ38383872
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trialQ38393318
In vitro and in vivo profiling of fadolmidine, a novel potent alpha(2)-adrenoceptor agonist with local mode of actionQ39927968
A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidineQ40190780
Protection of focal ischemic infarction by rilmenidine in the animal: evidence that interactions with central imidazoline receptors may be neuroprotectiveQ40653987
Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanismsQ42035990
Bioavailability of dexmedetomidine after extravascular doses in healthy subjectsQ42760132
The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairmentQ43781326
Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptionsQ43905326
Effect of antisense knock-down of alpha(2a)- and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat.Q44050815
Meperidine exerts agonist activity at the alpha(2B)-adrenoceptor subtypeQ44096133
Learning and memory in agmatine-treated ratsQ44099934
Dexmedetomidine to facilitate drug withdrawalQ44293057
A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unitQ44320906
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptorsQ44343480
The use of dexmedetomidine to facilitate opioid and benzodiazepine detoxification in an infantQ44345532
Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three casesQ44863277
Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humansQ45030653
Dexmedetomidine as a total intravenous anesthetic agentQ45030659
Dexmedetomidine pharmacodynamics: Part II: Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteersQ45124955
Cardiac arrest, a preventable yet a possible risk of dexmedetomidine: fact or fiction?Q45163496
Central α2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidineQ46124863
Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia.Q46262412
Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgeryQ46528953
Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopyQ46624801
Pharmacokinetics of intravenous dexmedetomidine in children under 11 yr of age.Q46672587
A prospective, double-blind, randomized, placebo-controlled study of dexmedetomidine as an adjunct to epidural analgesia after thoracic surgeryQ46734402
Alpha2-adrenoceptor antagonists enhance responses of dorsal horn neurones to formalin induced inflammationQ47882652
P433issue4
P921main subjectdexmedetomidineQ412133
review articleQ7318358
P304page(s)276-283
P577publication date2010-12-03
P1433published inAmerican Journal of Hospice and Palliative MedicineQ4744247
P1476titleReview article: dexmedetomidine: does it have potential in palliative medicine?
P478volume28

Reverse relations

cites work (P2860)
Q39085270A case report of dexmedetomidine used to treat intractable pain and delirium in a tertiary palliative care unit
Q55403799Beneficial effects of dexmedetomidine on early postoperative cognitive dysfunction in pediatric patients with tonsillectomy.
Q42182792Clinical Assessment and Management of Delirium in the Palliative Care Setting
Q38245308Delirium in patients with cancer: assessment, impact, mechanisms and management.
Q36297368Dexmedetomidine as adjunct treatment for severe alcohol withdrawal in the ICU
Q36822176Evidence-based treatment of delirium in patients with cancer