The expanding universe of transposon technologies for gene and cell engineering.

scientific article published on 07 December 2010

The expanding universe of transposon technologies for gene and cell engineering. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1024943437
P356DOI10.1186/1759-8753-1-25
P932PMC publication ID3016246
P698PubMed publication ID21138556
P5875ResearchGate publication ID49664894

P50authorZsuzsanna IzsvákQ21264884
Zoltán IvicsQ62559996
P2860cites workMutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cellsQ24561411
Transposon-based screens for cancer gene discovery in mouse modelsQ24607185
Transposon-mediated genome manipulation in vertebratesQ24623786
A transposon and transposase system for human applicationQ24630047
Comparative analysis of transposable element vector systems in human cellsQ24631012
Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon systemQ24631198
A transposon-based genetic screen in mice identifies genes altered in colorectal cancerQ24655169
Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genesQ24657906
The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon endsQ24683138
Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidosesQ24684749
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1Q28210584
Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebratesQ28243550
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1Q28290118
Embryonic stem cells use ZFP809 to silence retroviral DNAsQ28592550
RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissuesQ40337912
A role for LEDGF/p75 in targeting HIV DNA integrationQ40346940
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and miceQ40386192
Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference.Q40452758
Endothelial targeting of the Sleeping Beauty transposon within lungQ40539279
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon systemQ41734970
Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administrationQ41848708
Distribution of unlinked receptor sites for transposed Ac elements from the bz-m2(Ac) allele in maizeQ41928146
A complementary transposon tool kit for Drosophila melanogaster using P and piggyBacQ42045441
Structure-based prediction of insertion-site preferences of transposons into chromosomesQ42105719
Transposition pattern of the maize element Ds in Arabidopsis thalianaQ42111788
Ac transposition from a T-DNA can generate linked and unlinked clusters of insertions in the tomato genomeQ42133520
Frog Prince transposon-based RNAi vectors mediate efficient gene knockdown in human cellsQ42141814
Tol2 transposon-mediated enhancer trap to identify developmentally regulated zebrafish genes in vivo.Q42467500
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouseQ42812392
Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators.Q44104372
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.Q44260023
Germline transgenesis of zebrafish using the medaka Tol1 transposon systemQ44289920
Phi c31 integrase induces chromosomal aberrations in primary human fibroblastsQ44532550
Cis-acting gene regulatory activities in the terminal regions of sleeping beauty DNA transposon-based vectorsQ44657867
Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.Q45855517
Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon systemQ45865092
Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon systemQ45879828
Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon systemQ45884918
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastomaQ45886735
Variable Patterns of Transposition of the Maize Element Activator in TobaccoQ46442372
Pattern of somatic transposition in a high copy Ac tomato lineQ46572833
Stable nonviral genetic correction of inherited human skin diseaseQ46930709
Transposon-tagged mutagenesis in the rat.Q50701612
Generation of trangenic Xenopus laevis using the Sleeping Beauty transposon systemQ50716321
Tol2 transposon-mediated transgenesis in Xenopus tropicalisQ50719398
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.Q51929568
Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio.Q52189894
Conspiracy of silence among repeated transgenes.Q52565473
Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line.Q52591034
Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons.Q53055421
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.Q53356315
De novo methylation and expression of retroviral genomes during mouse embryogenesis.Q53564569
Transgenic tomato lines containing Ds elements at defined genomic positions as tools for targeted transposon taggingQ72054348
Safety of retroviral gene marking with a truncated NGF receptorQ73200787
Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon systemQ80448597
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon systemQ81251466
Sleeping beauty vector system moves toward human trials in the United StatesQ81825058
A simple and highly efficient transgenesis method in mice with the Tol2 transposon system and cytoplasmic microinjectionQ83170058
A fresh look at iPS cellsQ83608099
An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cellsQ84519931
Postintegrative gene silencing within the Sleeping Beauty transposition systemQ28756070
High-resolution genome-wide mapping of transposon integration in mammalsQ28769896
Regulated transposition of a fish transposon in the mouse germ lineQ28776165
Effective targeted gene 'knockdown' in zebrafishQ29547445
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cellsQ29617246
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cellsQ29619409
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastomaQ29622835
Nicotine response genetics in the zebrafish.Q30491214
Transposition and gene disruption in the male germline of the mouseQ30679435
Gene-trap mutagenesis: past, present and beyondQ30728811
Transposon-mediated BAC transgenesis in zebrafish and miceQ30876024
Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposonQ33247992
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemersQ33258825
A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cellsQ33411245
Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bankQ33463610
Genome-wide analysis of Tol2 transposon reintegration in zebrafishQ33500833
Tagged mutagenesis by efficient Minos-based germ line transpositionQ33514592
Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cellsQ33552685
Multiplexed transposon-mediated stable gene transfer in human cellsQ33667400
Generating knockout rats by transposon mutagenesis in spermatogonial stem cellsQ33915502
Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.Q33930324
In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissuesQ33944636
Transposition of Ac from the P locus of maize into unreplicated chromosomal sitesQ33953309
Preferential transposition of Drosophila P elements to nearby chromosomal sitesQ33960456
Mammalian germ-line transgenesis by transposition.Q34048682
It takes two transposons to tango: transposable-element-mediated chromosomal rearrangementsQ34069643
Harnessing transposons for cancer gene discoveryQ34138263
Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouseQ34144518
Gene transfer into genomes of human cells by the sleeping beauty transposon system.Q34211504
Sleeping beauty transposition: biology and applications for molecular therapyQ34294570
Development of hyperactive sleeping beauty transposon vectors by mutational analysisQ34294577
Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Q34343757
Sleeping beauty transposon-mediated gene therapy for prolonged expressionQ34442366
Hyperactive transposase mutants of the Sleeping Beauty transposonQ34449374
Gene therapy: X-SCID transgene leukaemogenicityQ34567588
Transposons for gene therapy!Q34577690
Genome-wide mapping of PiggyBac transposon integrations in primary human T cellsQ37485093
Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell diseaseQ37487093
Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cellsQ37496439
Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowthQ38409047
Targeted Sleeping Beauty transposition in human cellsQ38480971
Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation.Q39666687
MTID: a database of Sleeping Beauty transposon insertions in miceQ39790322
Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery.Q39856750
Generation of an inducible and optimized piggyBac transposon system.Q40118227
Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integrationQ40214917
The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cellsQ40315373
Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposonQ40319528
PiggyBac transposon-mediated gene transfer in human cellsQ34590383
Transposon Mutagenesis of the Mouse GermlineQ34618543
Characterization of Sleeping Beauty transposition and its application to genetic screening in miceQ34989563
Germ-line transgenesis of the Tc1/mariner superfamily transposon Minos in Ciona intestinalisQ35146657
Trans-kingdom transposition of the maize dissociation elementQ35176012
Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineageQ35290320
Chance or necessity? Insertional mutagenesis in gene therapy and its consequencesQ35637501
Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignanciesQ35962978
Transposition of the mariner element from Drosophila mauritiana in zebrafishQ36065690
DNA transposons in vertebrate functional genomicsQ36072055
Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.Q36186475
Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapyQ36187534
Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectivesQ36187544
Awakening gene therapy with Sleeping Beauty transposonsQ36220906
Hopping around the tumor genome: transposons for cancer gene discoveryQ36305153
Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.Q36311669
Insertional mutagenesis of the Drosophila genome with single P elementsQ36312073
Sleeping beauty: a novel cancer gene discovery toolQ36465173
Sleeping beauty transposon-mediated nonviral gene therapyQ36531992
Characterization of the transposition pattern of the Ac element in Arabidopsis thaliana using endonuclease I-SceI.Q36554374
piggyBac can bypass DNA synthesis during cut and paste transpositionQ36570713
Site-selected insertion of the transposon Tc1 into a Caenorhabditis elegans myosin light chain geneQ36660763
Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty systemQ36713904
Chromosomal transposition of PiggyBac in mouse embryonic stem cellsQ36737096
Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cellsQ36868712
Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistanceQ36870325
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.Q36915086
A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in miceQ36980093
Efficient transposition of the Tol2 transposable element from a single-copy donor in zebrafishQ37018923
Passport, a native Tc1 transposon from flatfish, is functionally active in vertebrate cells.Q37118761
Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A miceQ37241328
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.Q37266967
Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethalityQ37407179
P433issue1
P304page(s)25
P577publication date2010-12-07
P1433published inMobile DNAQ15816655
P1476titleThe expanding universe of transposon technologies for gene and cell engineering
P478volume1

Reverse relations

cites work (P2860)
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