Current concepts in the neuropathology and pathogenesis of multiple sclerosis

scientific article published on September 2010

Current concepts in the neuropathology and pathogenesis of multiple sclerosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1017/S0317167100022381
P698PubMed publication ID21246930

P2093author name stringG R Wayne Moore
P2860cites workMitochondrial defects in acute multiple sclerosis lesionsQ24648580
The pathogenesis of lesions and normal-appearing white matter changes in multiple sclerosis: a serial diffusion MRI studyQ28141600
Pathological abnormalities in the normal-appearing white matter in multiple sclerosisQ28198901
Evolution of focal and diffuse magnetisation transfer abnormalities in multiple sclerosisQ28202767
Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosisQ28215006
Relapsing and remitting multiple sclerosis: pathology of the newly forming lesionQ28253124
Homogeneity of active demyelinating lesions in established multiple sclerosisQ28266507
Myelin water imaging of multiple sclerosis at 7 T: Correlations with histopathologyQ29391773
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelinationQ29614990
Axonal transection in the lesions of multiple sclerosisQ29615585
Remyelination in the CNS: from biology to therapyQ30040587
A pathology-MRI study of the short-T2 component in formalin-fixed multiple sclerosis brainQ30620238
MRI-clinical correlations: more than inflammation alone-what can MRI contribute to improve the understanding of pathological processes in MS?Q30764951
Magnetic resonance studies of abnormalities in the normal appearing white matter and grey matter in multiple sclerosisQ30886085
Multicentre proton magnetic resonance spectroscopy imaging of primary progressive multiple sclerosisQ30940050
Diffusion MRI in multiple sclerosisQ31019997
Myelin water imaging in multiple sclerosis: quantitative correlations with histopathologyQ31096488
Longitudinal changes in myelin water fraction in two MS patients with active diseaseQ33372488
Magnetization transfer MR imaging in multiple sclerosisQ33390856
Proton magnetic resonance spectroscopy in multiple sclerosisQ33390863
Multiple sclerosis: histopathologic and MR and/or CT correlation in 37 cases at biopsy and three cases at autopsyQ33648766
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosisQ34436332
Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosisQ34472062
Immunoglobulins and complement in postmortem multiple sclerosis tissueQ34937786
Diffusely abnormal white matter in chronic multiple sclerosis: imaging and histopathologic analysisQ34980436
Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter.Q34986741
Lesion heterogeneity in multiple sclerosis: a study of the relations between appearances on T1 weighted images, T1 relaxation times, and metabolite concentrationsQ35456727
Diffusion tensor imaging of post mortem multiple sclerosis brain.Q35842914
The pathology of multiple sclerosisQ36015087
Multiple sclerosis--the plaque and its pathogenesisQ36410882
Quantitative magnetic resonance of postmortem multiple sclerosis brain before and after fixationQ36456786
In vivo visualization of myelin water in brain by magnetic resonanceQ36736879
Magnetization transfer ratio and myelin in postmortem multiple sclerosis brainQ39693808
Elevated white matter myo-inositol in clinically isolated syndromes suggestive of multiple sclerosis.Q40512390
A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosisQ41494978
White matter extracellular matrix chondroitin sulfate/dermatan sulfate proteoglycans in multiple sclerosisQ43838103
N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerveQ43849057
Diffuse axonal and tissue injury in patients with multiple sclerosis with low cerebral lesion load and no disabilityQ44175661
Choline is increased in pre-lesional normal appearing white matter in multiple sclerosisQ44181544
Diffusely elevated cerebral choline and creatine in relapsing-remitting multiple sclerosisQ44483765
Oligodendrocyte apoptosis before immune attack in multiple sclerosis?Q45204467
Changes in cerebral perfusion precede plaque formation in multiple sclerosis: a longitudinal perfusion MRI studyQ47431179
Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination.Q47596113
Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltrationQ47680006
Disability in multiple sclerosis is related to normal appearing brain tissue MTR histogram abnormalities.Q48121366
Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesionsQ48126443
Multislice T1 relaxation time measurements in the brain using IR-EPI: reproducibility, normal values, and histogram analysis in patients with multiple sclerosisQ48136884
Imaging correlates of axonal swelling in chronic multiple sclerosis brainsQ48207806
Subpial demyelination in the cerebral cortex of multiple sclerosis patientsQ48233815
On classification of post-mortem multiple sclerosis plaques for neuroscientistsQ48255738
Multiple sclerosis. Pathology of recurrent lesionsQ48269367
Neocortical neuronal, synaptic, and glial loss in multiple sclerosisQ48413281
Thalamic neurodegeneration in multiple sclerosisQ48459257
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaquesQ48511548
Serial proton magnetic resonance spectroscopic imaging, contrast-enhanced magnetic resonance imaging, and quantitative lesion volumetry in multiple sclerosisQ48550799
Cortical demyelination in multiple sclerosis: a substrate for cognitive deficits?Q48559489
Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathologyQ48588737
Accumulation of cortical lesions in MS: relation with cognitive impairmentQ48618943
Correlation between NMR scan and brain slice data in multiple sclerosisQ48633765
Studies on the pathogenesis of multiple sclerosis. Participation of lysosomes on demyelination in the central nervous system white matter outside plaquesQ48699761
Cortical demyelination and diffuse white matter injury in multiple sclerosis.Q48726181
Axonal damage in acute multiple sclerosis lesionsQ48776354
Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesionsQ48777649
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesionsQ48791086
Dirty-appearing white matter in multiple sclerosis: preliminary observations of myelin phospholipid and axonal lossQ48906919
Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosisQ48962732
Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosisQ57374204
Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchangeQ61709608
Evidence for pathogenic heterogeneity in multiple sclerosisQ61709616
A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesionsQ61709674
Cortical lesions in multiple sclerosisQ63185098
The fine structure of chronically active multiple sclerosis plaquesQ67016916
Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaquesQ70974898
Abnormalities in the macroscopically normal white matter in cases of mild or spinal multiple sclerosis (MS)Q72003895
Biochemical alterations in multiple sclerosis lesions and normal-appearing white matter detected by in vivo 31P and 1H spectroscopic imagingQ72114019
Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosisQ72605880
Regression analysis of metabolite concentrations estimated from localized proton MR spectra of active and chronic multiple sclerosis lesionsQ73372496
Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosisQ74227216
The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosisQ74424550
Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosisQ74575038
Hypothalamic lesions in multiple sclerosisQ77411350
T2 hypointensity in the deep gray matter of patients with multiple sclerosis: a quantitative magnetic resonance imaging studyQ77486197
Multiple sclerosis: classification revisited reveals homogeneity and recapitulationQ80580092
P921main subjectmultiple sclerosisQ8277
pathogenesisQ372016
P304page(s)S5-15
P577publication date2010-09-01
P1433published inCanadian Journal of Neurological SciencesQ5030246
P1476titleCurrent concepts in the neuropathology and pathogenesis of multiple sclerosis
P478volume37 Suppl 2

Reverse relations

cites work (P2860)
Q59649454Elevated plasma homocysteine levels in patients with multiple sclerosis are associated with male gender
Q47697450Lipid Order Degradation in Autoimmune Demyelination Probed by Polarized Coherent Raman Microscopy.
Q34357957Low serum urate levels are associated to female gender in multiple sclerosis patients.
Q31044261Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE).
Q35918951Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats
Q38754337Phospholipase D1 expression analysis in relapsing-remitting multiple sclerosis patients.
Q91843454Raman Techniques: Fundamentals and Frontiers
Q36831144The evidence for hypoperfusion as a factor in multiple sclerosis lesion development
Q36500155Upregulation of vascular endothelial growth factor receptor-3 in the spinal cord of Lewis rats with experimental autoimmune encephalomyelitis

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