Thalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma

scientific article published on February 2011

Thalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1586/EHM.10.83
P698PubMed publication ID21322778

P50authorKenneth C. AndersonQ28421846
Paul G. RichardsonQ87712102
Jacob P LaubachQ87769541
Robert SchlossmanQ114300414
Constantine S MitsiadesQ117224720
P2860cites workThalidomide is an inhibitor of angiogenesisQ24563363
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Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trialQ28252396
Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trialQ30433139
Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myelomaQ33367821
Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myelomaQ33369909
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Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myelomaQ34401962
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Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimensQ37533983
Importance of achieving a complete response in multiple myeloma, and the impact of novel agentsQ37729617
Impact of lenalidomide therapy on stem cell mobilization and engraftment post-peripheral blood stem cell transplantation in patients with newly diagnosed myelomaQ40201943
Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide.Q40450178
Thalidomide-induced sinus bradycardiaQ42166156
Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial.Q42914716
Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 StudyQ43048164
Bortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: updated follow-up and impact of subsequent therapy in the phase III VISTA trialQ43109172
Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myelomaQ43648034
Hypothyroidism in patients with multiple myeloma following treatment with thalidomideQ43923739
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implicationsQ44010411
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Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.Q44189620
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applicationsQ44211035
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Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myelomaQ44662272
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Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial.Q46006794
Influence of cytogenetics in patients with relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasone: adverse effect of deletion 17p13.Q46068547
Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedureQ46094234
Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myelomaQ46291462
Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitroQ46409873
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myelomaQ46505738
Azotemia associated with use of lenalidomide in plasma cell dyscrasiasQ46615368
Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma.Q46793597
Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology GroupQ46859424
Effect of lenalidomide therapy on mobilization of peripheral blood stem cells in previously untreated multiple myeloma patientsQ46886126
Lenalidomide-induced severe hepatotoxicityQ46913468
Long-term results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myelomaQ46972453
Thalidomide and hematopoietic-cell transplantation for multiple myelomaQ46981475
Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trialQ46985882
Bortezomib inhibits human osteoclastogenesis.Q52925512
Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome.Q53243787
Rapid response to high-dose steroids of severe bortezomib-related pulmonary complication in multiple myeloma.Q53470786
A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapyQ58050810
P433issue1
P921main subjectthalidomideQ203174
P304page(s)51-60
P577publication date2011-02-01
P1433published inExpert Review of HematologyQ15734429
P1476titleThalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma
P478volume4

Reverse relations

cites work (P2860)
Q47407841(Bortezomib plus lenalidomide/thalidomide)- vs. (bortezomib or lenalidomide/thalidomide)-containing regimens as induction therapy in newly diagnosed multiple myeloma: a meta-analysis of randomized controlled trials
Q49660927CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma
Q85084727Guest editorial: understanding the pathogenesis and the evolving treatment paradigm for multiple myeloma in the era of novel agents
Q38186797Immune reconstitution inflammatory syndrome associated with bacterial infections
Q39425529In search of the optimal platform for Post-Allogeneic SCT immunotherapy in relapsed multiple myeloma: a systematic review
Q39034873Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines
Q36675330Patterns of relapse and progression in multiple myeloma patients after auto-SCT: implications for patients' monitoring after transplantation
Q40795146Pomalidomide: a novel drug to treat relapsed and refractory multiple myeloma
Q38088003Proteasome inhibitors in acute leukemia.
Q33429980Siltuximab (CNTO 328) with lenalidomide, bortezomib and dexamethasone in newly-diagnosed, previously untreated multiple myeloma: an open-label phase I trial