review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Olavi Pelkonen | Q28028673 |
P2093 | author name string | Jukka Hakkola | |
Heikki Vapaatalo | |||
Jukka Mäenpää | |||
Marjo Volotinen | |||
P2860 | cites work | Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1. | Q24538817 |
Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy | Q24676890 | ||
New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland | Q28290062 | ||
Pharmacological therapy for glaucoma: a review | Q30860458 | ||
Current management of glaucoma | Q33199545 | ||
Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system | Q34466778 | ||
Inhibition and induction of human cytochrome P450 (CYP) enzymes | Q34487744 | ||
Genetic basis of glaucoma | Q34553228 | ||
Targeting outflow facility in glaucoma management | Q35174019 | ||
Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects | Q35257739 | ||
Ophthalmic drug delivery considerations at the cellular level: drug-metabolising enzymes and transporters | Q36316835 | ||
Glaucoma screening: current trends, economic issues, technology, and challenges | Q36427904 | ||
Ophthalmic timolol: plasma concentration and systemic cardiopulmonary effects. | Q36762112 | ||
Role of CYP1B1 in glaucoma | Q36960115 | ||
Barriers to glaucoma drug delivery | Q37111497 | ||
Expression of cytochrome P450 (CYP) enzymes in human nonpigmented ciliary epithelial cells: induction of CYP1B1 expression by TCDD. | Q39867733 | ||
Pharmacokinetics of topically applied ophthalmic drugs | Q40328899 | ||
The mechanism of timolol in lowering intraocular pressure. In the normal eye. | Q40963886 | ||
Recent advances in molecular genetics of glaucomas | Q41595926 | ||
Transport of timolol and tilisolol in rabbit corneal epithelium | Q42502203 | ||
Association of CYP2D6 single-nucleotide polymorphism with response to ophthalmic timolol in primary open-angle Glaucoma--a pilot study. | Q42868524 | ||
Effects of selective serotonin reuptake inhibitors on timolol metabolism in human liver microsomes and cryo-preserved hepatocytes | Q43242688 | ||
Drug transporter and cytochrome P450 mRNA expression in human ocular barriers: implications for ocular drug disposition | Q43452684 | ||
Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma | Q44674915 | ||
Cytochrome oxidase 2D6 gene polymorphism in primary open-angle glaucoma with various effects to ophthalmic timolol | Q46089600 | ||
Pharmacokinetic interactions of timolol with vasodilating drugs, food and phenobarbitone in healthy human volunteers. | Q51648124 | ||
Association between low plasma levels of ophthalmic timolol and haemodynamics in glaucoma patients. | Q53855923 | ||
Prevalence of open-angle glaucoma in central Sweden. The Tierp Glaucoma Survey. | Q53989484 | ||
Timolol Metabolism in Human Liver Microsomes Is Mediated Principally by CYP2D6 | Q58734950 | ||
P433 | issue | 5 | |
P304 | page(s) | 297-303 | |
P577 | publication date | 2011-05-01 | |
P1433 | published in | Basic and Clinical Pharmacology and Toxicology | Q15724438 |
P1476 | title | Metabolism of ophthalmic timolol: new aspects of an old drug | |
P478 | volume | 108 |