Chlamydia trachomatis heat shock proteins 60 and 10 induce apoptosis in endocervical epithelial cells

scientific article published on 05 August 2010

Chlamydia trachomatis heat shock proteins 60 and 10 induce apoptosis in endocervical epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00011-010-0237-X
P698PubMed publication ID20686813
P5875ResearchGate publication ID45506213

P50authorHarsh VardhanQ14647783
P2093author name stringSylvette Bas
Sudha Salhan
Aruna Mittal
Rajneesh Jha
P2860cites workChlamydia trachomatis genes whose products are related to energy metabolism are expressed differentially in active vs. persistent infectionQ37872657
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathwayQ37872780
Expression of Chlamydia trachomatis genes encoding products required for DNA synthesis and cell division during active versus persistent infectionQ37873521
Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activationQ37873723
Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotypingQ37875844
Chlamydia trachomatis infection of epithelial cells induces the activation of caspase-1 and release of mature IL-18.Q37876036
Can serology diagnose upper genital tract Chlamydia trachomatis infections? Studies on women with pelvic pain, with or without chlamydial plasmid DNA in endometrial biopsy tissueQ37881732
Prevalence and correlates of antibody to chlamydial heat shock protein in women attending sexually transmitted disease clinics and women with confirmed pelvic inflammatory diseaseQ37882753
Humoral immune response to membrane components of Chlamydia trachomatis and expression of human 60 kDa heat shock protein in follicular fluid of in-vitro fertilization patientsQ37882875
Antibody to chlamydial hsp60 predicts an increased risk for chlamydial pelvic inflammatory diseaseQ37882975
The presence of serum antibody to the chlamydial heat shock protein (CHSP60) as a diagnostic test for tubal factor infertilityQ37883335
Risk factors for Chlamydia trachomatis pelvic inflammatory disease among sex workers in Nairobi, KenyaQ37884951
Immune response to Chlamydia trachomatis heat-shock protein in infertile female patients and influence of Chlamydia pneumoniae antibodiesQ37886113
Serologic responses of infertile women to the 60-kd chlamydial heat shock protein (hsp60)Q37886389
Association between antibody to the chlamydial heat-shock protein and tubal infertilityQ37890162
Chlamydia trachomatis-associated ectopic pregnancy: serologic and histologic correlatesQ37893071
Chlamydia trachomatis: its role in tubal infertilityQ37903719
Helicobacter pylori heat-shock protein 60 induces inflammatory responses through the Toll-like receptor-triggered pathway in cultured human gastric epithelial cellsQ40483845
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cellsQ40799740
Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells.Q41143793
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma productionQ50335883
Overexpression of TLR2 and TLR4 susceptibility to serum deprivation-induced apoptosis in CHO cells.Q51813270
Differences in cytokine mRNA profiles between premalignant and malignant lesions of the uterine cervixQ78128730
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cellsQ22009395
The apoptotic signaling pathway activated by Toll-like receptor-2Q22254416
Cross-reactivity between Chlamydia trachomatis heat shock protein 10 and early pregnancy factorQ24675374
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cellsQ30304035
Antigenic profiling of a Chlamydia trachomatis gene-expression libraryQ30841178
Chlamydial heat shock proteins and disease pathology: new paradigms for old problems?Q33609632
Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophagesQ33842925
The role of heat shock proteins in reproductionQ33899698
The modulation of host cell apoptosis by intracellular bacterial pathogensQ33957483
Chlamydia trachomatis serology: diagnostic value of outer membrane protein 2 compared with that of other antigens.Q33974047
Serological investigation of Chlamydia trachomatis heat shock protein 10Q34002106
Seroreactivity to Chlamydia trachomatis Hsp10 correlates with severity of human genital tract diseaseQ34003078
Bacterial anti-apoptotic activitiesQ34674527
A universal role for MyD88 in TLR/IL-1R-mediated signalingQ34825992
Antibodies to the chlamydial 60 kilodalton heat shock protein in women with tubal factor infertilityQ35615519
Chlamydia and apoptosis: life and death decisions of an intracellular pathogen.Q35892057
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infectionQ36421541
Molecular characterization of the gene for human interleukin-1 beta converting enzyme (IL1BC).Q36734581
Interaction of chlamydiae and host cells in vitroQ37056842
Cervical epithelial cells from Chlamydia trachomatis-infected sites coexpress higher levels of chlamydial heat shock proteins 60 and 10 in infertile women than in fertile womenQ37854541
NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniaeQ37861433
Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4.Q37861922
Serological markers of persistent C. trachomatis infections in women with tubal factor subfertilityQ37865779
Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivoQ37866477
Cytokine expression pattern in the genital tract of Chlamydia trachomatis positive infertile women - implication for T-cell responsesQ37866607
Follicular fluid antibodies to Chlamydia trachomatis and human heat shock protein-60 kDa and infertility in women.Q37867603
Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory responseQ37870496
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniaeQ37871262
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
Chlamydia trachomatisQ131065
P304page(s)69-78
P577publication date2010-08-05
P1433published inInflammation ResearchQ1819367
P1476titleChlamydia trachomatis heat shock proteins 60 and 10 induce apoptosis in endocervical epithelial cells
P478volume60

Reverse relations

cites work (P2860)
Q37835361Abnormal Expression of TRAIL Receptors in Decidual Tissue of Chlamydia trachomatis-Infected Rats During Early Pregnancy Loss
Q38095686Chaperonin 60: a paradoxical, evolutionarily conserved protein family with multiple moonlighting functions.
Q36674111Characterization and function analysis of Hsp60 and Hsp10 under different acute stresses in black tiger shrimp, Penaeus monodon
Q36492709Chlamydial plasmid-encoded protein pORF5 induces production of IL-1β and IL-18 via NALP3 inflammasome activation and p38 MAPK pathway
Q42016102Effect of r-Mt-Cpn10 on human osteoblast cells
Q37850515Heat shock protein 10 of Chlamydophila pneumoniae induces proinflammatory cytokines through Toll-like receptor (TLR) 2 and TLR4 in human monocytes THP-1.
Q34130460Lack of effective anti-apoptotic activities restricts growth of Parachlamydiaceae in insect cells