Bioinformatics meets parasitology.

scientific article published on May 2012

Bioinformatics meets parasitology. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1365-3024.2011.01304.X
P698PubMed publication ID21615422
P5875ResearchGate publication ID51167983

P50authorShoba RanganathanQ17489039
Aaron R JexQ59657009
Cinzia CantacessiQ37375310
Robin B. GasserQ42326677
Neil D. YoungQ30518653
P2093author name stringB E Campbell
R S Hall
P2860cites workDrug target prediction and prioritization: using orthology to predict essentiality in parasite genomesQ21267230
The DNA sequence and biological annotation of human chromosomeQ21735919
Gene ontology: tool for the unification of biologyQ23781406
Rescuing the bottom billion through control of neglected tropical diseasesQ24290723
Hierarchical docking of databases of multiple ligand conformationsQ24538548
DNA Data Bank of Japan (DDBJ) for genome scale research in life scienceQ24548418
The EMBL Nucleotide Sequence DatabaseQ24548433
An Eulerian path approach to DNA fragment assemblyQ24555762
RNA-Seq: a revolutionary tool for transcriptomicsQ24596169
Genetic and physical maps of Saccharomyces cerevisiaeQ24599455
Epidemiology and control of human gastrointestinal parasites in childrenQ24601973
Accurate whole human genome sequencing using reversible terminator chemistryQ24641887
WormBase: a comprehensive resource for nematode researchQ24642944
The Pfam protein families databaseQ24644670
InterPro: the integrative protein signature databaseQ24655685
BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009Q24655817
Velvet: algorithms for de novo short read assembly using de Bruijn graphsQ24657623
Advantages of combined transmembrane topology and signal peptide prediction--the Phobius web serverQ24684376
Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashionQ42693655
Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cellsQ43072073
Collagen processing and cuticle formation is catalysed by the astacin metalloprotease DPY-31 in free-living and parasitic nematodesQ43420386
The first two cantharidin analogues displaying PP1 selectivityQ43868992
Two hypotheses to explain why RNA interference does not work in animal parasitic nematodesQ44309125
Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheepQ44594907
Gene expression profiles associated with the transition to parasitism in Ancylostoma caninum larvae.Q44862785
RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 moltingQ45157453
Bioinformatic analysis of abundant, gender-enriched transcripts of adult Ascaris suum (Nematoda) using a semi-automated workflow platform.Q46372338
Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninumQ46407310
Serpin expression in the parasitic stages of Trichostrongylus vitrinus, an ovine intestinal nematodeQ46408773
Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegansQ46722469
High-performance signal peptide prediction based on sequence alignment techniquesQ47402726
Considerations to improve functional annotations in biological databasesQ47622426
Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayiQ47845860
A broad spectrum Kunitz type serine protease inhibitor secreted by the hookworm Ancylostoma ceylanicum.Q47846060
X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infectionQ48150544
A developmentally regulated cysteine protease gene family in Haemonchus contortusQ48246657
Discovery of veterinary antiparasitic agents in the 21st century: a view from industryQ48824908
Efficacy and specificity of RNA interference in larval life-stages of Ostertagia ostertagiQ49078242
Mining the Leishmania genome for novel antigens and vaccine candidates.Q51830208
Assembling millions of short DNA sequences using SSAKE.Q51926970
RNA interference in parasitic nematodes of animals: a reality check?Q51995373
A combined bioinformatics and chemoinformatics approach for the development of new antiparasitic drugs.Q52673753
Development of methods for RNA interference in the sheep gastrointestinal parasite, Trichostrongylus colubriformis.Q54482282
RNA interference in Haemonchus contortus: suppression of beta-tubulin gene expression in L3, L4 and adult worms in vitro.Q54633809
Prediction of Transmembrane Topology and Signal Peptide Given a Protein’s Amino Acid SequenceQ57909982
Heterocyclic substituted cantharidin and norcantharidin analogues—synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activityQ58200454
Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivityQ58200463
SPD--a web-based secreted protein databaseQ24796109
Investigating hookworm genomes by comparative analysis of two Ancylostoma speciesQ24803534
OrfPredictor: predicting protein-coding regions in EST-derived sequencesQ24812401
SPdb--a signal peptide database.Q24812642
WormBase: better software, richer contentQ25257908
Basic local alignment search toolQ25938991
Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genomeQ27496583
Improved prediction of signal peptides: SignalP 3.0Q27860548
Sequencing technologies - the next generationQ27860568
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomesQ27860838
CAP3: A DNA sequence assembly programQ27860964
The Pfam protein families database.Q27861012
The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routesQ28204640
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookwormQ28238731
SOAP: short oligonucleotide alignment programQ28266228
The impact of next-generation sequencing technology on geneticsQ28268088
Next-generation DNA sequencing methodsQ28285066
The PROSITE database, its status in 1999Q28291019
Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larvaQ28472116
Genomic-bioinformatic analysis of transcripts enriched in the third-stage larva of the parasitic nematode Ascaris suumQ28472910
Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs)Q28473708
Massively parallel sequencing and analysis of the Necator americanus transcriptomeQ28473882
Computational prediction and experimental assessment of secreted/surface proteins from Mycobacterium tuberculosis H37RvQ28474670
Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interferenceQ28474713
A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoniQ28474728
The key role of genomics in modern vaccine and drug design for emerging infectious diseasesQ28476274
Archiving next generation sequencing dataQ28749233
ABySS: a parallel assembler for short read sequence dataQ29547263
The druggable genomeQ29547361
Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics researchQ29547461
A combined transmembrane topology and signal peptide prediction methodQ29615817
Soil-transmitted helminth infections: updating the global pictureQ29619026
Applications of next-generation sequencing technologies in functional genomicsQ29619225
FlyBase: enhancing Drosophila Gene Ontology annotationsQ29619306
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2Q30480412
WormBase: new content and better accessQ34581089
RNA interference in parasitic helminths: current situation, potential pitfalls and future prospectsQ34597487
Free resources to assist structure-based virtual ligand screening experimentsQ34662757
Transgenesis in parasitic nematodes: building a better arrayQ34732349
Single-molecule DNA sequencing of a viral genomeQ34767716
Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adultsQ34768601
KOBAS server: a web-based platform for automated annotation and pathway identificationQ34974449
Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expressionQ35143303
Genomics and its impact on parasitology and the potential for development of new parasite control methods.Q35195166
Digestive proteases of blood-feeding nematodes.Q35212643
Identification and characterisation of an aspartyl protease inhibitor homologue as a major allergen of Trichostrongylus colubriformis.Q35295215
Modulation of host immune responses by nematode cystatinsQ35295296
Genomic filtering: an approach to discovering novel antiparasiticsQ35885277
ESTExplorer: an expressed sequence tag (EST) assembly and annotation platformQ35914279
Strategies for the design of potent and selective kinase inhibitors.Q36126762
Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cellsQ36184194
Progresses in the field of drug design to combat tropical protozoan parasitic diseasesQ36395593
The canine hookworm genome: analysis and classification of Ancylostoma caninum survey sequencesQ36491789
Prospects for exploring molecular developmental processes in Haemonchus contortus.Q36499366
De novo bacterial genome sequencing: millions of very short reads assembled on a desktop computerQ36586588
Hookworm vaccines: past, present, and futureQ36635886
Vaccines against blood-feeding nematodes of humans and livestockQ36726742
Integrating transcriptome, proteome and glycome analyses of Schistosoma biologyQ36750479
Oesophagostomum dentatum: potential as a model for genomic studies of strongylid nematodes, with biotechnological prospectsQ36756560
Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targetsQ36856455
CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin.Q37242270
An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infectionQ37326963
Sequence assembly.Q37372054
A portrait of the "SCP/TAPS" proteins of eukaryotes--developing a framework for fundamental research and biotechnological outcomes.Q37400340
Elucidating ANTs in worms using genomic and bioinformatic tools--biotechnological prospects?Q37601057
Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi ToolboxQ37645064
Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasitesQ37756146
Our wormy world genomics, proteomics and transcriptomics in East and southeast Asia.Q37772267
Serine/threonine phosphatases in socioeconomically important parasitic nematodes—Prospects as novel drug targets?Q37781877
Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugsQ37832015
Exploring transcriptional conservation between Ancylostoma caninum and Haemonchus contortus by oligonucleotide microarray and bioinformatic analysesQ38359451
The Mouse Genome Database (MGD): mouse biology and model systemsQ38393159
SecretP: a new method for predicting mammalian secreted proteinsQ39913057
Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeuticQ40745426
PCAP: a whole-genome assembly programQ40830110
The potential of farnesyltransferase inhibitors as cancer chemotherapeuticsQ41455731
Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanusQ42162237
Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanusQ42411728
The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanusQ42626863
First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approachQ30540149
A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookwormsQ30763295
Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortusQ30821319
A comprehensive assessment of N-terminal signal peptides prediction methodsQ30951432
Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortusQ31119735
Molecular characterisation of a male-specific serine/threonine phosphatase from Oesophagostomum dentatum (Nematoda: Strongylida), and functional analysis of homologues in Caenorhabditis elegansQ31137061
Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninumQ31152995
In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer workflow platform with conventional database searchesQ33322197
A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanusQ33337600
CleanEST: a database of cleansed EST librariesQ33373612
Antimalarial drug discovery: in silico structural biology and rational drug design.Q33466461
SeqTrim: a high-throughput pipeline for pre-processing any type of sequence readQ33525367
Mechanism-based screening: discovery of the next generation of anthelmintics depends upon more basic researchQ33537035
Assembly algorithms for next-generation sequencing dataQ33538377
Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortusQ33565038
Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptationQ33578293
RNA-seq: from technology to biologyQ33604404
A practical, bioinformatic workflow system for large data sets generated by next-generation sequencingQ33648646
Ascaris suum: RNAi mediated silencing of enolase gene expression in infective larvaeQ33651918
Structural and functional characterisation of the fork head transcription factor-encoding gene, Hc-daf-16, from the parasitic nematode Haemonchus contortus (Strongylida)Q33786575
PRINTS-S: the database formerly known as PRINTS.Q33883200
Immune evasion genes from filarial nematodesQ34282175
Toward simplifying and accurately formulating fragment assemblyQ34290064
A new algorithm for DNA sequence assemblyQ34290071
Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of wormsQ34318119
Testing the efficacy of RNA interference in Haemonchus contortus.Q34493166
A hitchhiker's guide to expressed sequence tag (EST) analysisQ34537805
P433issue5
P921main subjectparasitologyQ180502
bioinformaticsQ128570
P304page(s)265-275
P577publication date2012-05-01
P1433published inParasite ImmunologyQ15751559
P1476titleBioinformatics meets parasitology
P478volume34

Reverse relations

cites work (P2860)
Q28485368Molecular changes in Opisthorchis viverrini (Southeast Asian liver fluke) during the transition from the juvenile to the adult stage
Q37177725New approaches for understanding mechanisms of drug resistance in schistosomes
Q44452249Next-generation sequencing in clinical microbiology
Q28533259Proteomic analysis of Oesophagostomum dentatum (Nematoda) during larval transition, and the effects of hydrolase inhibitors on development
Q46886975Testing the Hamilton-Zuk hypothesis: past, present, and future
Q38820297The omic approach to parasitic trematode research-a review of techniques and developments within the past 5 years
Q53743985Vaccination against parasites - status quo and the way forward.