| P2093 | author name string | Hiroshi Takayanagi | |
| | Kazuo Okamoto | |
| P2860 | cites work | Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor | Q73490934 |
| | Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis | Q73490940 |
| | Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells | Q74187456 |
| | Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation | Q79544847 |
| | The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4 | Q80737734 |
| | Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm | Q81503729 |
| | Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations | Q24310432 |
| | Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 |
| | Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 |
| | TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells | Q24315251 |
| | Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis | Q24324701 |
| | A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function | Q24336057 |
| | IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis | Q24563235 |
| | RANK is essential for osteoclast and lymph node development | Q24598872 |
| | osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification | Q24603266 |
| | The AP-1 transcription factor Batf controls T(H)17 differentiation | Q24644525 |
| | Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 |
| | IL-17 and Th17 Cells | Q27860566 |
| | The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells | Q27860620 |
| | Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families | Q28137631 |
| | Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice | Q28140546 |
| | Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis | Q28141482 |
| | RANK-L and RANK: T cells, bone loss, and mammalian evolution | Q28203468 |
| | A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis | Q28255805 |
| | Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor | Q28273769 |
| | Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency | Q28284581 |
| | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems | Q28294477 |
| | T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma | Q28506783 |
| | TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling | Q28513445 |
| | Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts | Q28583027 |
| | OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 |
| | IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells | Q28591227 |
| | Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice | Q28593712 |
| | The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. | Q29347247 |
| | Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 | Q29347250 |
| | Regulatory T cells and immune tolerance | Q29616864 |
| | Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts | Q29618116 |
| | Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. | Q46711436 |
| | B cells activated in the presence of Th1 cytokines inhibit osteoclastogenesis | Q47349703 |
| | Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis | Q47761859 |
| | Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. | Q48083226 |
| | Osteoprotegerin deficiency and juvenile Paget's disease | Q48292818 |
| | Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. | Q50335960 |
| | Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss. | Q51802618 |
| | B cells play an important role in lipopolysaccharide-induced bone resorption. | Q52026400 |
| | Connection between B lymphocyte and osteoclast differentiation pathways. | Q52130852 |
| | High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors. | Q52525666 |
| | Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. | Q52584877 |
| | Regulatory T cells protect from local and systemic bone destruction in arthritis. | Q53294686 |
| | Osteoblastic cells are involved in osteoclast formation. | Q54374668 |
| | Treg cells suppress osteoclast formation: a new link between the immune system and bone | Q56900960 |
| | Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation | Q57253491 |
| | NF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1 | Q57675122 |
| | T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ | Q59064307 |
| | IκBζ regulates TH17 development by cooperating with ROR nuclear receptors | Q59067213 |
| | The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 |
| | Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines | Q60524890 |
| | Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures | Q68274092 |
| | Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint | Q72824611 |
| | Activated T lymphocytes support osteoclast formation in vitro | Q73149439 |
| | Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice | Q73370075 |
| | Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand | Q29619331 |
| | The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins | Q29620097 |
| | NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism | Q30157499 |
| | Estrogen enhances the functions of CD4(+)CD25(+)Foxp3(+) regulatory T cells that suppress osteoclast differentiation and bone resorption in vitro | Q33784120 |
| | Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta | Q34331980 |
| | B cells move to centre stage: novel opportunities for autoimmune disease treatment | Q34544062 |
| | Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency | Q34816640 |
| | Osteoclasts are essential for TNF-alpha-mediated joint destruction | Q34826003 |
| | Plasticity of CD4+ T cell lineage differentiation. | Q34982725 |
| | B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease | Q35222008 |
| | Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation | Q35747144 |
| | TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis | Q35788463 |
| | B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo | Q35804512 |
| | Fos/AP-1 proteins in bone and the immune system | Q36324940 |
| | Bone quality--the material and structural basis of bone strength and fragility | Q36488553 |
| | Osteoclasts, rheumatoid arthritis, and osteoimmunology | Q36501073 |
| | Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency | Q36566505 |
| | IkappaB-zeta: an inducible regulator of nuclear factor-kappaB. | Q36617105 |
| | Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells | Q36652900 |
| | Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation | Q36732543 |
| | New complexities in helper T cell fate determination and the implications for autoimmune diseases | Q37001149 |
| | RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism | Q37108966 |
| | Interleukin-7 in rheumatoid arthritis. | Q37115100 |
| | Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. | Q37408959 |
| | Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody | Q37423212 |
| | Osteoimmunology and the effects of the immune system on bone | Q37626412 |
| | The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase | Q37647341 |
| | B-cell targeted therapies in human autoimmune diseases: an updated perspective | Q37781401 |
| | How important are T cells in chronic rheumatoid synovitis? | Q37938120 |
| | Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells | Q38506162 |
| | Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin | Q39116155 |
| | Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors | Q40489394 |
| | B lymphocytes inhibit human osteoclastogenesis by secretion of TGFbeta | Q40875461 |
| | Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction | Q41927546 |
| | Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy | Q42971266 |
| | Autoamplification of NFATc1 expression determines its essential role in bone homeostasis | Q42972503 |
| | Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesis | Q44514609 |
| | Calcineurin/NFAT signaling in osteoblasts regulates bone mass | Q46675973 |
| P433 | issue | 3 | |
| P921 | main subject | tissue | Q40397 |
| | arthritis | Q170990 |
| | human musculoskeletal system | Q726543 |
| | adaptive immune system | Q1645075 |
| | bone disease | Q4941552 |
| P304 | page(s) | 219 | |
| P577 | publication date | 2011-05-27 | |
| P1433 | published in | Arthritis Research and Therapy | Q15757229 |
| P1476 | title | Regulation of bone by the adaptive immune system in arthritis | |
| P478 | volume | 13 | |