Targeting of Toll-like receptors: a decade of progress in combating infectious diseases

scientific article published on 28 June 2011

Targeting of Toll-like receptors: a decade of progress in combating infectious diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1473-3099(11)70099-8
P698PubMed publication ID21719349

P50authorMihai NeteaQ24517868
Nima RezaeiQ26464741
P2093author name stringMona Hedayat
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Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA.Q44833577
Imiquimod 5% cream for external genital or perianal warts in human immunodeficiency virus-positive patients treated with highly active antiretroviral therapy: an open-label, noncomparative study.Q45384251
CPG 7909 adjuvant plus hepatitis B virus vaccination in HIV-infected adults achieves long-term seroprotection for up to 5 yearsQ45395440
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Secretory IgA antibodies provide cross-protection against infection with different strains of influenza B virusQ45596016
MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist (E6020).Q46102734
Randomized, double-blind clinical trial of topical imiquimod 5% with parenteral meglumine antimoniate in the treatment of cutaneous leishmaniasis in PeruQ46448535
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The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in MaliQ37456934
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.Q37497786
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotidesQ38289912
Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine responseQ38334354
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Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signalingQ40489306
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Phase 2 trial of eritoran tetrasodium (E5564), a toll-like receptor 4 antagonist, in patients with severe sepsisQ28254097
Clinical update of the AS04-adjuvanted human papillomavirus-16/18 cervical cancer vaccine, CervarixQ28268292
The effect of combinations of ampligen and zidovudine or dideoxyinosine against human immunodeficiency viruses in vitroQ28319338
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Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.Q33211563
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Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malariaQ33359552
Toll-like receptor 4 decoy, TOY, attenuates gram-negative bacterial sepsisQ33509524
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A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adultsQ33598040
Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge.Q33768989
Toll-like receptor signaling inhibits hepatitis B virus replication in vivo.Q33788761
Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.Q33967257
Crystal structure of human toll-like receptor 3 (TLR3) ectodomainQ33987865
Recombinant gp350 vaccine for infectious mononucleosis: a phase 2, randomized, double-blind, placebo-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adultsQ34009363
The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individualsQ34021580
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primatesQ34085119
Toll-like receptor 2 controls expansion and function of regulatory T cellsQ34264024
CpG motifs in bacterial DNA trigger direct B-cell activationQ34307394
Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestisQ34334406
Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifsQ34355633
Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trialQ34359432
Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infectionQ34444955
Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonistQ34531671
CpG motifs in bacterial DNA and their immune effectsQ34542287
GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectivesQ34655188
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Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protectionQ34990090
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7Q35143849
Toll-like receptors and T-helper-1/T-helper-2 responsesQ35160610
Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine.Q35277985
Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agentsQ35842681
Inhibition of endotoxin response by synthetic TLR4 antagonistsQ35848256
Aluminium compounds for use in vaccinesQ35915759
Synthetic Toll-like receptor 4 agonist enhances vaccine efficacy in an experimental model of toxic shock syndromeQ36313592
American Gastroenterological Association technical review on the management of hepatitis C.Q36364156
Therapeutic potential of Toll-like receptor 9 activationQ36501229
New hepatitis B vaccine formulated with an improved adjuvant systemQ36780117
Topical imiquimod: a review of its use in the management of anogenital warts, actinic keratoses, basal cell carcinoma and other skin lesionsQ36967164
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvantQ36973053
Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulationQ37004584
Cell-penetrating peptides for drug delivery across membrane barriersQ37039034
Adjuvanted intranasal Norwalk virus-like particle vaccine elicits antibodies and antibody-secreting cells that express homing receptors for mucosal and peripheral lymphoid tissuesQ37044185
Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primatesQ37051021
TLR3: interferon induction by double-stranded RNA including poly(I:C).Q37080631
Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvantQ37109519
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.Q37114768
A review of the role of CpG oligodeoxynucleotides as toll-like receptor 9 agonists in prophylactic and therapeutic vaccine development in infectious diseasesQ37154750
Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseasesQ37169130
Structures of TLR-ligand complexesQ37201808
Structures of the toll-like receptor family and its ligand complexesQ37242985
Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: results of a Phase I randomized trialQ37253541
Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyondQ37286716
Ampligen: a potential toll-like 3 receptor adjuvant for immunotherapy of cancerQ37387913
The roles of TLRs, RLRs and NLRs in pathogen recognitionQ37402176
P433issue9
P921main subjecttoll-like receptorQ408004
P1104number of pages11
P304page(s)702-712
P577publication date2011-06-28
P13046publication type of scholarly workreview articleQ7318358
P1433published inLancet Infectious DiseasesQ15724248
P1476titleTargeting of Toll-like receptors: a decade of progress in combating infectious diseases
P478volume11

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