Prothrombin complex concentrate for critical bleeding

scientific article published on 05 July 2011

Prothrombin complex concentrate for critical bleeding is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1345/APH.1Q096
P698PubMed publication ID21730276
P5875ResearchGate publication ID51468355

P2093author name stringAsad E Patanwala
Nicole M Acquisto
Brian L Erstad
P2860cites workEvidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation testsQ45881452
Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supratherapeutic international normalized ratio due to warfarin overdoseQ46125200
Massive, fatal, intracardiac thrombosis associated with prothrombin complex concentrateQ46139632
Optimal dose of prothrombin complex concentrate for acute reversal of oral anticoagulationQ46405965
Warfarin reversal with prothrombin complex concentrate confers better antifibrinolytic activity compared with recombinant activated factor VII.Q46818855
Efficacy and safety of a prothrombin complex concentrate (Octaplex) for rapid reversal of oral anticoagulationQ47266490
Availability of information for dosing injectable medications in underweight or obese patientsQ48969476
Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol.Q50732476
Coagulopathy does not protect against venous thromboembolism in hospitalized patients with chronic liver disease.Q51792687
Comparison of fresh frozen plasma and prothrombin complex concentrate for the reversal of oral anticoagulants in patients undergoing cardiopulmonary bypass surgery: a randomized studyQ53167882
Urgent reversal of warfarin with prothrombin complex concentrate.Q53255644
Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospitalQ21195016
AASLD position paper: the management of acute liver failureQ28246028
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trialQ28285511
Use of factor IX complex in warfarin-related intracranial hemorrhageQ28375864
Recombinant activated factor VII for coagulopathy in fulminant hepatic failure compared with conventional therapyQ30310461
Prothrombin complex concentrates: indications, contraindications, and risks: a task force summaryQ33330139
Coagulopathy in liver diseasesQ33389863
Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulationQ33647003
Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathyQ33735132
Thrombogenicity of prothrombin complex concentratesQ33739978
Replacement of coagulation factors in liver or multiple organ dysfunctionQ33739998
Management of bleeding following major trauma: an updated European guidelineQ33919178
Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).Q34012421
Remodeling the blood coagulation cascadeQ34294608
Mechanisms of thrombus formationQ34815800
Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients.Q35688850
Coagulopathy in the trauma patientQ36314566
Update on transfusion medicineQ36920718
Role of prothrombin complex concentrates in reversing warfarin anticoagulation: a review of the literatureQ36923137
Prothrombin complex concentrates: a brief reviewQ37185539
Perioperative hemostatic management of patients treated with vitamin K antagonistsQ37306386
Correction of coagulopathy in warfarin associated cerebral hemorrhageQ37418713
Prevention and treatment of bleeding complications in patients receiving vitamin K antagonists, part 2: TreatmentQ37554147
Coagulopathy in critically ill patients: part 2-soluble clotting factors and hemostatic testingQ37668852
New insights into acute coagulopathy in trauma patientsQ37733473
Factor Xa inhibitors: next-generation antithrombotic agentsQ37760921
Resuscitation and coagulation in the severely injured trauma patientQ37819627
Prothrombin complex concentrate for oral anticoagulant reversal in neurosurgical emergenciesQ42046164
Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma modelQ43180952
Prothrombin complex concentrate versus recombinant factor VIIa for reversal of hemodilutional coagulopathy in a porcine trauma modelQ43227114
Prothrombin complex concentrate (Beriplex P/N) for control of bleeding after kidney trauma in a rabbit dilutional coagulopathy modelQ43242257
Emergency reversal of anticoagulation after intracerebral hemorrhageQ43574102
Beriplex P/N reverses severe warfarin-induced overanticoagulation immediately and completely in patients presenting with major bleedingQ43885621
Rapid reversal of oral anticoagulation with warfarin by a prothrombin complex concentrate (Beriplex): efficacy and safety in 42 patientsQ43889363
Efficacy and safety of a prothrombin complex concentrate with two virus-inactivation steps in patients with severe liver damageQ45729423
P433issue7-8
P407language of work or nameEnglishQ1860
P921main subjectprothrombin complex concentrateQ2044524
P304page(s)990-999
P577publication date2011-07-05
P1433published inAnnals of PharmacotherapyQ4767858
P1476titleProthrombin complex concentrate for critical bleeding
P478volume45

Reverse relations

cites work (P2860)
Q38191128Coagulopathy after severe pediatric trauma
Q34485905Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients
Q38197728Four factor prothrombin complex concentrate (human): review of the pharmacology and clinical application for vitamin K antagonist reversal
Q37999699Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors
Q38232683Improving appropriateness of blood utilization through prospective review of requests for blood products: the role of pathology residents as consultants
Q55452572Is fast reversal and early surgery (within 24 h) in patients on warfarin medication with trochanteric hip fractures safe? A case-control study.
Q35457130Obesity increases risk of anticoagulation reversal failure with prothrombin complex concentrate in those with intracranial hemorrhage
Q38171412Optimizing the dose of three-factor prothrombin complex concentrate in traumatic brain injury patients on warfarin therapy
Q47883018Prothrombin complex concentrate reversal of warfarin in patients with hip fracture
Q38014751Prothrombin complex concentrates in emergency bleeding disorders
Q35481316Prothrombin complex concentrates utility for warfarin-associated hemorrhage.
Q44380447Rapid bedside coagulometry prior to urgent neurosurgical procedures in anticoagulated patients
Q38009420Reversal of drug-induced anticoagulation: old solutions and new problems
Q39022849Role of agents for reversing the effects of target-specific oral anticoagulants
Q33420178Rotation thromboelastometry analysis of clot formation and fibrinolysis in severe thrombocytopenia: effect of fibrinogen, activated prothrombin complex concentrate, and thrombin- activatable fibrinolysis inhibitor
Q85370189Should direct thrombin inhibitors replace warfarin for prophylaxis of thromboembolism in canadians with atrial fibrillation?
Q52331525Three- versus four-factor prothrombin complex concentrate for the reversal of warfarin-induced bleeding.

Search more.