review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Nobutaka Hattori | Q64780524 |
P2093 | author name string | Shigeto Sato | |
P2860 | cites work | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 |
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis | Q22242250 | ||
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 | Q24297155 | ||
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy | Q24299149 | ||
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability | Q24299939 | ||
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis | Q24304952 | ||
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1 | Q24312106 | ||
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
The kinase domain of mitochondrial PINK1 faces the cytoplasm | Q24321709 | ||
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons | Q24322788 | ||
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection | Q24324226 | ||
Hereditary early-onset Parkinson's disease caused by mutations in PINK1 | Q24337084 | ||
Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36 | Q24536382 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
alpha-Synuclein locus triplication causes Parkinson's disease | Q27860533 | ||
Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications | Q28241852 | ||
Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease | Q28317593 | ||
Chronic parkinsonism secondary to intravenous injection of meperidine analogues | Q28323857 | ||
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease | Q28371129 | ||
Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease. | Q54626622 | ||
Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects. | Q54651745 | ||
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease | Q69356679 | ||
Mitochondrial complex I deficiency in Parkinson's disease | Q69370277 | ||
Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity by 1-methyl-4-phenylpyridinium ion | Q70330687 | ||
Role of parkin mutations in 111 community-based patients with early-onset parkinsonism | Q74448267 | ||
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism | Q79249169 | ||
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease | Q80794093 | ||
??? | Q64819937 | ||
??? | Q64867043 | ||
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress | Q28592727 | ||
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. | Q28593258 | ||
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease | Q29547175 | ||
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin | Q29547423 | ||
Parkinson's disease: mechanisms and models | Q29547424 | ||
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease | Q29614762 | ||
Chronic systemic pesticide exposure reproduces features of Parkinson's disease | Q29614763 | ||
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants | Q29615627 | ||
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin | Q29615684 | ||
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy | Q29616005 | ||
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy | Q29620567 | ||
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin | Q29622838 | ||
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity | Q30502685 | ||
Novel PINK1 mutations in early-onset parkinsonism | Q34345898 | ||
PINK1 (PARK6) associated Parkinson disease in Ireland | Q34362007 | ||
Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. | Q34394747 | ||
Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism | Q34426475 | ||
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin | Q34520638 | ||
Protocol for the MPTP mouse model of Parkinson's disease | Q34614573 | ||
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization | Q34836156 | ||
Mitochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease. | Q35171006 | ||
Distribution, type, and origin of Parkin mutations: review and case studies | Q35897345 | ||
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. | Q36446511 | ||
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery | Q36657599 | ||
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Q37343442 | ||
Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism. | Q37466094 | ||
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease | Q37671552 | ||
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation | Q39924212 | ||
Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1. | Q40046504 | ||
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1. | Q40285081 | ||
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism | Q42216349 | ||
Parkin disease: a phenotypic study of a large case series | Q44451919 | ||
An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells | Q44642551 | ||
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease | Q44808814 | ||
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function | Q46797053 | ||
Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen antagonists | Q47842152 | ||
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication | Q48298527 | ||
Rotenone neurotoxicity: a new window on environmental causes of Parkinson's disease and related brain amyloidoses | Q48418414 | ||
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine | Q48477579 | ||
Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism | Q48581847 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | Parkinson's disease | Q11085 |
P304 | page(s) | 979231 | |
P577 | publication date | 2011-08-01 | |
P1433 | published in | Parkinson's disease | Q27723341 |
P1476 | title | Genetic mutations and mitochondrial toxins shed new light on the pathogenesis of Parkinson's disease | |
P478 | volume | 2011 |
Q38370162 | Mitochondrial mechanisms of redox cycling agents implicated in Parkinson's disease |
Q42180022 | Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson's Disease |
Q21563375 | Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria |
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