The human epidermal growth factor receptor 2 (HER2).

scientific article published on 15 September 2011

The human epidermal growth factor receptor 2 (HER2). is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1515/CCLM.2011.707
P698PubMed publication ID21919545

P2093author name stringGregory J Tsongalis
Laura J Tafe
P2860cites workUse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Lapatinib plus capecitabine for HER2-positive advanced breast cancerQ27851403
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trialQ27851578
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
Untangling the ErbB signalling networkQ27860884
Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare eventQ28245213
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cellsQ28282744
Trastuzumab--mechanism of action and use in clinical practiceQ29615810
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancerQ29616112
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancerQ29617440
HER2 status in ovarian carcinomas: a multicenter GINECO study of 320 patientsQ33305210
Assessing HER2 gene amplification as a potential target for therapy in invasive urothelial bladder cancer with a standardized methodology: results in 1005 patients.Q33751191
HER2-positive circulating tumor cells in breast cancerQ33802925
HER2 and chromosome 17 effect on patient outcome in the N9831 adjuvant trastuzumab trialQ34194672
Emerging technologies for assessing HER2 amplificationQ34659152
Immunohistochemical and molecular analyses of HER2 status in breast cancers are highly concordant and complementary approachesQ35034555
The effects of fixation, processing and evaluation criteria on immunohistochemical detection of hormone receptors in breast cancerQ36814238
Delineation of HER2 gene status in breast carcinoma by silver in situ hybridization is reproducible among laboratories and pathologistsQ36944264
Assessment of a HER2 scoring system for gastric cancer: results from a validation studyQ37142266
Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerationsQ37388937
Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancerQ37626334
Assessment of HER2 gene status in breast carcinomas with polysomy of chromosome 17.Q38414983
Real time RT-PCR approach for the evaluation of ERBB2 overexpression in breast cancer archival samples: a comparative study with FISH, SISH, and immunohistochemistryQ38427140
Determination of HER2 gene amplification by fluorescence in situ hybridization and concordance with the clinical trials immunohistochemical assay in women with metastatic breast cancer evaluated for treatment with trastuzumabQ38440789
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trialQ39712731
Delay to formalin fixation effect on breast biomarkersQ43280139
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysisQ43294276
Human epidermal growth factor receptor 2 assessment in a case-control study: comparison of fluorescence in situ hybridization and quantitative reverse transcription polymerase chain reaction performed by central laboratories.Q45935030
Intratumoral heterogeneity of HER2/neu expression and its consequences for the management of advanced breast cancerQ46755338
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trialQ51751068
Chromogenic in situ hybridization: a multicenter study comparing silver in situ hybridization with FISH.Q53060420
Silver in situ hybridization (SISH) for determination of HER2 gene status in breast carcinoma: comparison with FISH and assessment of interobserver reproducibility.Q53067130
P433issue1
P921main subjectErb-b2 receptor tyrosine kinase 2Q415271
P304page(s)23-30
P577publication date2011-09-15
P1433published inClinical Chemistry and Laboratory MedicineQ5133754
P1476titleThe human epidermal growth factor receptor 2 (HER2).
P478volume50

Reverse relations

cites work (P2860)
Q37341891A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression
Q38133084Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine
Q33557258Overexpression of the HER2/neu Gene: A New Therapeutic Possibility for Patients With Advanced Gallbladder Cancer
Q44056799Serum HER-2: sensitivity, specificity, and predictive values for detecting metastatic recurrence in breast cancer patients.
Q37375636Usefulness of traditional serum biomarkers for management of breast cancer patients.

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