| scholarly article | Q13442814 |
| P50 | author | Kairbaan Hodivala-Dilke | Q28773350 |
| P2093 | author name string | Tanguy Lechertier | |
| P2860 | cites work | Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses | Q22010953 |
| Integrin-regulated FAK-Src signaling in normal and cancer cells | Q24300271 | ||
| Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53 | Q24300771 | ||
| Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain | Q24304270 | ||
| Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration | Q24318859 | ||
| Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions | Q24651203 | ||
| Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains | Q24672461 | ||
| Structural basis for the autoinhibition of focal adhesion kinase | Q24678318 | ||
| Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271 | Q27650074 | ||
| FAK integrates growth-factor and integrin signals to promote cell migration | Q28144169 | ||
| FAK regulates biological processes important for the pathogenesis of cancer | Q28190163 | ||
| Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells | Q28203628 | ||
| Codon-improved Cre recombinase (iCre) expression in the mouse | Q28218096 | ||
| Signal transduction by focal adhesion kinase in cancer | Q37377635 | ||
| Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation | Q37381921 | ||
| Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development | Q37454238 | ||
| Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer | Q37750751 | ||
| Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases | Q37883025 | ||
| Conditional deletion of the focal adhesion kinase FAK alters remodeling of the blood-brain barrier in glioma | Q39619926 | ||
| Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases | Q39729499 | ||
| Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma | Q40050554 | ||
| TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR. | Q40082132 | ||
| Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo | Q40146305 | ||
| Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction | Q40172193 | ||
| Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors | Q40282278 | ||
| Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model. | Q40302237 | ||
| Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation. | Q40478503 | ||
| p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain | Q40489224 | ||
| Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells | Q40561080 | ||
| Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells | Q40712152 | ||
| Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily | Q41296563 | ||
| Characterization of a novel focal adhesion kinase inhibitor in human platelets. | Q42139602 | ||
| Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. | Q42615205 | ||
| Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. | Q46079015 | ||
| Paradoxical roles of FAK in tumor cell migration and metastasis. | Q48434128 | ||
| Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells | Q28363361 | ||
| Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis | Q28591107 | ||
| Angiogenesis in health and disease | Q29614541 | ||
| Focal adhesion kinase: in command and control of cell motility | Q29615192 | ||
| Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice | Q29617498 | ||
| Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase | Q30304229 | ||
| Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment | Q30424344 | ||
| Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model | Q30435351 | ||
| Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells | Q30442000 | ||
| Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase | Q30442141 | ||
| Cellular characterization of a novel focal adhesion kinase inhibitor | Q30443304 | ||
| Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention | Q30445536 | ||
| Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion | Q30445760 | ||
| FERM domain interaction promotes FAK signaling | Q30449206 | ||
| Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK | Q30450284 | ||
| Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation | Q30452651 | ||
| Normalization of the vasculature for treatment of cancer and other diseases | Q30471456 | ||
| Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. | Q30480350 | ||
| Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation. | Q30495320 | ||
| Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics | Q30499765 | ||
| RAFTK/Pyk2-mediated cellular signalling | Q33855347 | ||
| Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development | Q33916059 | ||
| Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. | Q34087039 | ||
| Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models | Q34929239 | ||
| Integrins in angiogenesis: multitalented molecules in a balancing act. | Q35299292 | ||
| Control of motile and invasive cell phenotypes by focal adhesion kinase. | Q35832728 | ||
| Endothelial FAK is required for tumour angiogenesis | Q36039352 | ||
| The role of focal-adhesion kinase in cancer - a new therapeutic opportunity | Q36216076 | ||
| Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome | Q36344071 | ||
| Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. | Q36527182 | ||
| Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis | Q37152874 | ||
| Src and focal adhesion kinase as therapeutic targets in cancer | Q37215683 | ||
| FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion | Q37237616 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | tumor angiogenesis | Q110495869 |
| P304 | page(s) | 404-412 | |
| P577 | publication date | 2011-11-23 | |
| P1433 | published in | Journal of Pathology | Q400296 |
| P1476 | title | Focal adhesion kinase and tumour angiogenesis | |
| P478 | volume | 226 |
| Q36188833 | A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells |
| Q93007196 | A Novel Heterogalactan from Antrodia camphorata and Anti-Angiogenic Activity of Its Sulfated Derivative |
| Q34308216 | Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling |
| Q36296805 | Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors |
| Q37409084 | Aqp1 enhances migration of bone marrow mesenchymal stem cells through regulation of FAK and β-catenin |
| Q40977473 | Azithromycin effectively inhibits tumor angiogenesis by suppressing vascular endothelial growth factor receptor 2-mediated signaling pathways in lung cancer |
| Q50106997 | Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase. |
| Q90088036 | Cytosolic phospholipase A2α modulates cell-matrix adhesion via the FAK/paxillin pathway in hepatocellular carcinoma |
| Q36913661 | D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways |
| Q35919855 | Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model |
| Q50460738 | Effects of bioactive cements incorporating zinc-bioglass nanoparticles on odontogenic and angiogenic potential of human dental pulp cells. |
| Q92701768 | Exosomal L1CAM Stimulates Glioblastoma Cell Motility, Proliferation, and Invasiveness |
| Q90122397 | Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner |
| Q39711361 | FAK Expression, Not Kinase Activity, Is a Key Mediator of Thyroid Tumorigenesis and Protumorigenic Processes. |
| Q47797785 | FAK inhibitors in Cancer, a patent review |
| Q54282770 | FAK mediates a compensatory survival signal parallel to PI3K-AKT in PTEN-null T-ALL cells. |
| Q91334253 | Filopodia and focal adhesions: An integrated system driving branching morphogenesis in neuronal pathfinding and angiogenesis |
| Q38706013 | Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium-specific FAK-kinase dead mice |
| Q36425657 | Focal adhesion kinase is a phospho-regulated repressor of Rac and proliferation in human endothelial cells |
| Q37725641 | Focal adhesion kinases crucially regulate TGFβ-induced migration and invasion of bladder cancer cells via Src kinase and E-cadherin |
| Q39125536 | Generation of point-mutant FAK knockin mice. |
| Q89966968 | High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer |
| Q34423151 | High focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype |
| Q59149996 | Imidazoles as potential anticancer agents |
| Q36336487 | Inhibition of focal adhesion kinase induces apoptosis in bladder cancer cells via Src and the phosphatidylinositol 3-kinase/Akt pathway |
| Q36592509 | Inhibition of integrin β1 decreases the malignancy of ovarian cancer cells and potentiates anticancer therapy via the FAK/STAT1 signaling pathway |
| Q48218297 | Integrin β1 controls VE-cadherin localization and blood vessel stability |
| Q42868438 | Integrin β1: A Mechanosignaling Sensor Essential for Connective Tissue Deposition by Fibroblasts |
| Q91361879 | Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy |
| Q42829073 | Integrins as Modulators of Transforming Growth Factor Beta Signaling in Dermal Fibroblasts During Skin Regeneration After Injury |
| Q35238499 | MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis |
| Q38854580 | Molecular Pathways: Endothelial Cell FAK-A Target for Cancer Treatment. |
| Q48314829 | Monitoring focal adhesion kinase phosphorylation dynamics in live cells |
| Q39159197 | Multiplexed tyrosine kinase activity detection in cancer cells using a hydrogel immobilized substrate |
| Q50066099 | New Scaffold for Angiogenesis Inhibitors Discovered by Targeted Chemical Transformations of Wondonin Natural Products. |
| Q27014164 | New insights into FAK function and regulation during spermatogenesis |
| Q33754877 | Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER⁺ Breast Cancer Cells |
| Q35920837 | Novel Role of Src in Priming Pyk2 Phosphorylation |
| Q37946790 | Omnis cellula e cellula revisited: cell biology as the foundation of pathology |
| Q46835643 | P311 modulates hepatic stellate cells migration |
| Q96136190 | Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth |
| Q38313097 | Perlecan domain V inhibits amyloid-β induced brain endothelial cell toxicity and restores angiogenic function |
| Q39698792 | Pigment epithelium-derived factor (PEDF): a novel trophoblast-derived factor limiting feto-placental angiogenesis in late pregnancy. |
| Q39011125 | Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth |
| Q38772661 | Rap2B promotes cell proliferation, migration and invasion in prostate cancer |
| Q54120290 | SPP1 promotes ovarian cancer progression via Integrin β1/FAK/AKT signaling pathway. |
| Q57135431 | Stromal collagen type VI associates with features of malignancy and predicts poor prognosis in salivary gland cancer |
| Q38175738 | Targeting FAK in human cancer: from finding to first clinical trials |
| Q96231055 | Targeting focal adhesion kinase in cancer cells and the tumor microenvironment |
| Q34173290 | Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer |
| Q51524514 | Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis. |
| Q58712101 | The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer |
| Q35137962 | Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer. |
| Q35009792 | Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights |
| Q34480730 | VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling |
| Q38767839 | Vascular disrupting activity of combretastatin analogues |
| Q36465259 | Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice |
| Q88984504 | von Willebrand factor regulation of blood vessel formation |
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