| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S10555-011-9306-Z |
| P698 | PubMed publication ID | 22038018 |
| P2093 | author name string | Karin Müller-Decker | |
| P2860 | cites work | Human cyclooxygenase-2 cDNA | Q24293134 |
| Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes | Q24310434 | ||
| Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis | Q24652945 | ||
| Merkel cells are essential for light-touch responses | Q24655694 | ||
| Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. | Q27863328 | ||
| Surfing the p53 network | Q28032484 | ||
| Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis | Q28143403 | ||
| Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues | Q28192400 | ||
| Nonsteroidal anti-inflammatory drugs and the risk of actinic keratoses and squamous cell cancers of the skin | Q28193593 | ||
| Merkel cell carcinoma: more deaths but still no pathway to blame | Q40093442 | ||
| 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer | Q40248466 | ||
| Cyclooxygenase-2 overexpression in human basal cell carcinoma cell line increases antiapoptosis, angiogenesis, and tumorigenesis. | Q40306645 | ||
| Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity | Q40522782 | ||
| Altered pain perception and inflammatory response in mice lacking prostacyclin receptor | Q40646776 | ||
| The role of p38 in UVA-induced cyclooxygenase-2 expression in the human keratinocyte cell line, HaCaT. | Q40698825 | ||
| Progression and NSAID-induced apoptosis in malignant melanomas are independent of cyclooxygenase II. | Q40766192 | ||
| Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes | Q40783200 | ||
| Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes | Q40794472 | ||
| Direct and indirect modulation of ornithine decarboxylase and cyclooxygenase by UVB radiation in human skin cells | Q40957625 | ||
| Basal cell carcinoma. Identification and treatment of the high-risk patient | Q40969359 | ||
| Immunity at the surface: homeostatic mechanisms of the skin immune system. | Q40997580 | ||
| Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues | Q41004291 | ||
| Cholecalciferol induces prostaglandin E2 biosynthesis and transglutaminase activity in human keratinocytes | Q41004398 | ||
| Keratins and the skin | Q41020944 | ||
| The significance of polyunsaturated fatty acids in cutaneous biology | Q41053429 | ||
| Differential expression of prostaglandin-H synthase isoenzymes in normal and activated keratinocytes in vivo and in vitro | Q41330461 | ||
| Phorbol ester TPA- and bradykinin-induced arachidonic acid release from keratinocytes is catalyzed by a cytosolic phospholipase A2 (cPLA2). | Q41521998 | ||
| Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin | Q42045620 | ||
| UV radiation inhibits 15-hydroxyprostaglandin dehydrogenase levels in human skin: evidence of transcriptional suppression | Q42114996 | ||
| Effect of non-steroidal anti-inflammatory drugs on non-melanoma skin cancer incidence in the SKICAP-AK trial | Q42449647 | ||
| Inhibition of cutaneous ultraviolet light B–mediated inflammation and tumor formation with topical celecoxib treatment | Q42450437 | ||
| Expression of cyclooxygenase isozymes during morphogenesis and cycling of pelage hair follicles in mouse skin: precocious onset of the first catagen phase and alopecia upon cyclooxygenase-2 overexpression | Q42453130 | ||
| COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer | Q42457056 | ||
| Localization of prostaglandin-H synthase-1 and -2 in mouse skin: implications for cutaneous function | Q42458240 | ||
| Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2. | Q42462178 | ||
| COX-2 expression correlates with microvessel density in non-melanoma skin cancer from renal transplant recipients and immunocompetent individuals | Q42472269 | ||
| Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin | Q42475288 | ||
| Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition | Q42478216 | ||
| Effect of NSAIDs on the recurrence of nonmelanoma skin cancer | Q42491269 | ||
| Immunohistochemical expression of cyclooxygenase-2 in skin cancers | Q42505683 | ||
| Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes | Q42508495 | ||
| The expression pattern of prostaglandin E synthase and EP receptor isoforms in normal mouse skin and preinvasive skin neoplasms | Q42511158 | ||
| Cyclooxygenases in human and mouse skin and cultured human keratinocytes: association of COX-2 expression with human keratinocyte differentiation. | Q42516522 | ||
| Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches | Q42523881 | ||
| Cyclooxygenase-1-Coupled Prostaglandin Biosynthesis Constitutes an Essential Prerequisite for Skin Repair | Q42802697 | ||
| Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials | Q42849516 | ||
| Cardiovascular hazard and non-steroidal anti-inflammatory drugs | Q28210980 | ||
| Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2 | Q28253346 | ||
| Regulatory mechanism and physiological role of cytosolic phospholipase A2 | Q28276569 | ||
| Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) | Q28586461 | ||
| The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis | Q29616121 | ||
| Cyclooxygenases: structural, cellular, and molecular biology | Q29616510 | ||
| Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention | Q29620087 | ||
| Possible involvement of enhanced prostaglandin E2 production in the photosensitivity in xeroderma pigmentosum group A model mice | Q30835294 | ||
| Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5'-flanking regulatory sequences | Q31111891 | ||
| Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen | Q31634572 | ||
| Carcinogen substrate specificity of human COX-1 and COX-2. | Q31835278 | ||
| Ultraviolet B(UVB)-induced cox-2 expression in murine skin: an immunohistochemical study | Q31856494 | ||
| The pathogenesis of melanoma induced by ultraviolet radiation | Q33603082 | ||
| Regulation and inhibition of phospholipase A2. | Q33636666 | ||
| Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials | Q33767211 | ||
| Prostaglandins in bone: bad cop, good cop? | Q33823316 | ||
| Cancer chemoprevention through interruption of multistage carcinogenesis. The lessons learnt by comparing mouse skin carcinogenesis and human large bowel cancer | Q33857570 | ||
| Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner | Q33895949 | ||
| Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice | Q33950621 | ||
| UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer | Q33955751 | ||
| The state-of-the-art in chemoprevention of skin cancer | Q33959730 | ||
| Eicosanoids and cancer | Q33966203 | ||
| Cyclooxygenase isoforms in human skin | Q34097368 | ||
| Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management | Q34129236 | ||
| Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis | Q34156486 | ||
| Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer | Q34200712 | ||
| Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis | Q34247727 | ||
| Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema | Q34258861 | ||
| Prevention of non-melanoma skin cancer | Q34272004 | ||
| Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation | Q34348569 | ||
| Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial. | Q34406418 | ||
| The epidemiology of UV induced skin cancer | Q34421835 | ||
| Increased prostaglandins E2 and F2alpha in human skin at 6 and 24 h after ultraviolet B irradiation (290- 320 nm) | Q34516526 | ||
| Is inhibition of cyclooxygenase required for the anti-tumorigenic effects of nonsteroidal, anti-inflammatory drugs (NSAIDs)? In vitro versus in vivo results and the relevance for the prevention and treatment of cancer | Q34537518 | ||
| Langerhans cells release prostaglandin D2 in response to nicotinic acid | Q34569907 | ||
| Ultraviolet-B-induced erythema is mediated by nitric oxide and prostaglandin E2 in combination | Q43776988 | ||
| Celecoxib, a cyclooxygenase 2 inhibitor as a potential chemopreventive to UV-induced skin cancer: a study in the hairless mouse model | Q44022563 | ||
| Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine | Q44216606 | ||
| The effects of cyclooxygenase isozyme inhibition on incisional wound healing in mouse skin | Q44224881 | ||
| Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation | Q44295673 | ||
| Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. | Q44311834 | ||
| Selective cyclooxygenase-2 inhibition does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice | Q44316605 | ||
| Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice. | Q44456402 | ||
| Involvement of EGF receptor activation in the induction of cyclooxygenase-2 in HaCaT keratinocytes after UVB. | Q44557326 | ||
| Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer | Q44569620 | ||
| Enhanced expression of cylooxygenase-2 by UV in aged human skin in vivo | Q44590042 | ||
| Proteinase-activated receptor-2 stimulates prostaglandin production in keratinocytes: analysis of prostaglandin receptors on human melanocytes and effects of PGE2 and PGF2alpha on melanocyte dendricity | Q44893957 | ||
| Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors. | Q44919275 | ||
| NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer | Q45052764 | ||
| Treatment of actinic keratoses on the dorsum of the hands: ALA-PDT versus diclofenac 3% gel followed by ALA-PDT. A placebo-controlled, double-blind, pilot study | Q46049367 | ||
| Selective cyclooxygenase-2 inhibition produces heterogeneous erythema response to ultraviolet irradiation | Q46850921 | ||
| Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands | Q46875614 | ||
| Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases | Q47910140 | ||
| Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. | Q48580352 | ||
| Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours. | Q51914466 | ||
| Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. | Q52013322 | ||
| Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. | Q52518081 | ||
| Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. | Q52518083 | ||
| The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent. | Q53331977 | ||
| Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure. | Q53337738 | ||
| Cyclooxygenase-2 expression in primary Merkel cell carcinoma. | Q53361545 | ||
| Expression of PGF(2alpha) receptor mRNA in normal, hyperplastic and neoplastic skin. | Q53410442 | ||
| Cyclooxygenase-2 expression in primary and metastatic Merkel cell carcinoma. | Q53468746 | ||
| 12-O-tetradecanoylphorbol-13-acetate and the induction of prostaglandin E2 generation by human keratinocytes: a re-evaluation. | Q53474996 | ||
| Role of prostaglandin-mediated vasodilatation in inflammation | Q59071312 | ||
| Mechanisms regulating epithelial stratification | Q36816002 | ||
| A proposed COX-2 and PGE(2) receptor interaction in UV-exposed mouse skin | Q36849877 | ||
| The proliferating field of neural crest stem cells | Q36933338 | ||
| Cancer as an overhealing wound: an old hypothesis revisited | Q37217254 | ||
| Molecular pathogenesis of cutaneous melanocytic neoplasms | Q37463075 | ||
| Cancer prevention: from 1727 to milestones of the past 100 years | Q37505772 | ||
| Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect | Q37605758 | ||
| Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models | Q37693268 | ||
| Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. | Q37700833 | ||
| A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors | Q38337677 | ||
| Prostaglandin D production in FM55 melanoma cells is regulated by alpha-melanocyte-stimulating hormone and is not related to melanin production | Q39702684 | ||
| Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP. | Q39726376 | ||
| Role of HuR and p38MAPK in ultraviolet B-induced post-transcriptional regulation of COX-2 expression in the human keratinocyte cell line HaCaT. | Q39773895 | ||
| Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction. | Q39931086 | ||
| UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes | Q39986567 | ||
| Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling | Q39995485 | ||
| Prostaglandin E2, prostaglandin I2 and the vascular changes of inflammation | Q40065493 | ||
| The Role of Arachidonic Acid Oxygenation Products in Pain and Inflammation | Q40081115 | ||
| Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer. | Q34571903 | ||
| The epidemiology of skin cancer | Q34609498 | ||
| Getting under the skin of epidermal morphogenesis | Q34611868 | ||
| Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer | Q34629053 | ||
| Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells | Q34681473 | ||
| Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis | Q34687966 | ||
| Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression | Q34835869 | ||
| Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells | Q34887778 | ||
| p38 MAP kinase plays a functional role in UVB-induced mouse skin carcinogenesis | Q34970703 | ||
| Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. | Q34997948 | ||
| Prostaglandin transport | Q34998052 | ||
| 15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis | Q35033202 | ||
| Electrical stimulation of wound healing | Q35168521 | ||
| The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs | Q35234371 | ||
| The role of COX-2 in intestinal inflammation and colorectal cancer | Q35234704 | ||
| Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications | Q35542147 | ||
| Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents? | Q35557450 | ||
| Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling | Q35610059 | ||
| Prostaglandin synthases: recent developments and a novel hypothesis. | Q35610805 | ||
| Basal cell carcinomas: attack of the hedgehog | Q35687900 | ||
| UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression | Q35690270 | ||
| Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch | Q35732971 | ||
| Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. | Q35829067 | ||
| Nonsteroidal anti-inflammatory drug use in the prevention and treatment of squamous cell carcinoma | Q35905546 | ||
| Budesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1beta-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes | Q36012290 | ||
| Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells | Q36042811 | ||
| Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4. | Q36153789 | ||
| Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin | Q36319222 | ||
| Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion). | Q36416837 | ||
| Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis | Q36459962 | ||
| NSAIDs and cancer prevention: targets downstream of COX-2. | Q36651702 | ||
| Melanocyte biology and skin pigmentation | Q36742011 | ||
| Melanoma biology and new targeted therapy | Q36742015 | ||
| Inflammatory mediators and nuclear receptor signaling in colorectal cancer | Q36765419 | ||
| P433 | issue | 3-4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pharmacology | Q128406 |
| carcinogenesis | Q1637543 | ||
| P304 | page(s) | 343-361 | |
| P577 | publication date | 2011-12-01 | |
| P1433 | published in | Cancer and Metastasis Reviews | Q2647982 |
| P1476 | title | Cyclooxygenase-dependent signaling is causally linked to non-melanoma skin carcinogenesis: pharmacological, genetic, and clinical evidence | |
| P478 | volume | 30 |
| Q34473373 | Age-Associated Increase in Skin Fibroblast-Derived Prostaglandin E2 Contributes to Reduced Collagen Levels in Elderly Human Skin |
| Q47243988 | Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils |
| Q38602543 | Basal cell carcinoma of the skin (part 1): epidemiology, pathology and genetic syndromes |
| Q38748824 | Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond |
| Q34685488 | Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin |
| Q33705269 | Cell-type-specific roles for COX-2 in UVB-induced skin cancer |
| Q26777814 | Combined Treatments with Photodynamic Therapy for Non-Melanoma Skin Cancer |
| Q37621197 | Cyclooxygenase in Cancer Prevention and Treatments for Actinic Keratosis |
| Q57476687 | Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature |
| Q36401953 | Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell-autonomous defect in tumor formation |
| Q38014084 | Immunotherapy in nonmelanoma skin cancer |
| Q34466680 | Increased level of serum prostaglandin-2 in early stage of esophageal squamous cell carcinoma |
| Q47141515 | Inhibition of cyclooxygenase-2 sensitizes lung cancer cells to radiation-induced apoptosis |
| Q35147941 | Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on case-control studies |
| Q27005678 | Multifocal epithelial tumors and field cancerization: stroma as a primary determinant |
| Q37686669 | New Enlightenment of Skin Cancer Chemoprevention through Phytochemicals: In Vitro and In Vivo Studies and the Underlying Mechanisms |
| Q38417725 | Nonsteroidal anti-inflammatory drugs and the risk of nonmelanoma skin cancer |
| Q38444433 | Pharmacogenomics of cyclooxygenases |
| Q90061920 | Potential of Curcumin in Skin Disorders |
| Q55108856 | Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway. |
| Q34486975 | Protective effects of a new phloretin derivative against UVB-induced damage in skin cell model and human volunteers |
| Q38135313 | Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesis. |
| Q36638287 | Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer |
| Q36546794 | Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome |
| Q89108747 | Targeting PRPK and TOPK for skin cancer prevention and therapy |
| Q44306547 | The association between cyclooxygenase-2 1195 G/A polymorphism and hepatocellular carcinoma: evidence from a meta-analysis |
| Q36983145 | The chemopreventive efficacies of nonsteroidal anti-inflammatory drugs: the relationship of short-term biomarkers to long-term skin tumor outcome |
| Q26775913 | The relevance of piroxicam for the prevention and treatment of nonmelanoma skin cancer and its precursors |
| Q34619895 | The tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin. |
| Q55162562 | Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation. |
| Q53229365 | [Parallels between wound healing, chronic inflammatory skin diseases and neoplasia: clinical aspects]. |
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