scholarly article | Q13442814 |
P356 | DOI | 10.1177/1074248411424145 |
P698 | PubMed publication ID | 22064668 |
P50 | author | John P Murad | Q56997598 |
P2093 | author name string | Fadi T Khasawneh | |
Harold J Ting | |||
Enma V P Espinosa | |||
P2860 | cites work | Differential Suppression of Thromboxane Biosynthesis by Indobufen and Aspirin in Patients With Unstable Angina | Q58230345 |
BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN | Q58481581 | ||
Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal | Q59065336 | ||
Cloning and expression of cDNA for a human thromboxane A2 receptor | Q24311759 | ||
G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C | Q24324791 | ||
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression | Q24536398 | ||
Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation | Q24562692 | ||
Synthesis and biological properties of pinane-thromboxane A2, a selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation | Q24596717 | ||
Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist | Q28167658 | ||
Role of prostacyclin in the cardiovascular response to thromboxane A2 | Q28192832 | ||
Improved endothelial function by the thromboxane A2 receptor antagonist S 18886 in patients with coronary artery disease treated with aspirin | Q28195607 | ||
Mapping of a ligand-binding site for the human thromboxane A2 receptor protein | Q28205029 | ||
G13-mediated signaling as a potential target for antiplatelet drugs | Q28211909 | ||
Molecular analysis of the interaction between the intracellular loops of the human serotonin receptor type 6 (5-HT6) and the alpha subunit of GS protein | Q28237275 | ||
Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway | Q28276490 | ||
Mechanism of action of fibrates on lipid and lipoprotein metabolism | Q28288187 | ||
GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro | Q28341988 | ||
Evidence that phospholipase delta1 is the effector in the Gh (transglutaminase II)-mediated signaling | Q28571919 | ||
Inositol trisphosphate, a novel second messenger in cellular signal transduction | Q29618048 | ||
The role of protein kinase C in cell surface signal transduction and tumour promotion | Q29618532 | ||
Thromboxane and the thromboxane receptor in cardiovascular disease | Q33899567 | ||
An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro | Q34185192 | ||
GAPs for rho-related GTPases | Q34319579 | ||
Aspirin as an antiplatelet drug | Q34338650 | ||
Signaling and regulation of the platelet glycoprotein Ib-IX-V complex | Q34616663 | ||
Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide | Q34986893 | ||
Acetylation of prostaglandin synthase by aspirin | Q35085661 | ||
Heterodimerization of the alpha and beta isoforms of the human thromboxane receptor enhances isoprostane signaling | Q35579014 | ||
Roles of G-protein-coupled receptor dimerization | Q35622424 | ||
Thromboxane, prostacyclin and isoprostanes: therapeutic targets in atherogenesis | Q36294176 | ||
Antagonism of thromboxane receptors by diclofenac and lumiracoxib | Q36358638 | ||
From the design to the clinical application of thromboxane modulators | Q36419627 | ||
Protease activated receptors: clinical relevance to hemostasis and inflammation | Q36720123 | ||
Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells | Q36823316 | ||
Characterization of isoprostane signaling: evidence for a unique coordination profile of 8-iso-PGF(2alpha) with the thromboxane A(2) receptor, and activation of a separate cAMP-dependent inhibitory pathway in human platelets | Q37010020 | ||
Aspirin resistance: focus on clinical endpoints | Q37334879 | ||
13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor | Q37341093 | ||
Prevention of nonsteroidal anti-inflammatory drug-induced gastropathy. | Q37370008 | ||
Determinants of bleeding risk in patients on antithrombotic and antifibrinolytic drugs. | Q37392176 | ||
The thromboxane/endoperoxide receptor (TP): the common villain | Q37737688 | ||
Antiplatelet drugs--do we need new options? With a reappraisal of direct thromboxane inhibitors | Q37738868 | ||
Platelets at work in primary hemostasis. | Q37865759 | ||
Thromboxane, prostaglandin and leukotriene receptors | Q38272494 | ||
Differential signaling by the thromboxane receptor isoforms via the novel GTP-binding protein, Gh. | Q38325669 | ||
Repurposing an old drug for a new use: glybenclamide exerts antiplatelet activity by interacting with the thromboxane A(2) receptor | Q39019862 | ||
The opsin family of proteins | Q39480645 | ||
Clinical implications of prostaglandin and thromboxane A2 formation (2). | Q39519430 | ||
Low expression of cell-surface thromboxane A2 receptor beta-isoform through the negative regulation of its membrane traffic by proteasomes | Q40133308 | ||
Differential mapping of the amino acids mediating agonist and antagonist coordination with the human thromboxane A2 receptor protein | Q40256331 | ||
The G12 family of G proteins as a reporter of thromboxane A2 receptor activity | Q40328440 | ||
Oligomerization of the alpha and beta isoforms of the thromboxane A2 receptor: relevance to receptor signaling and endocytosis | Q40422541 | ||
Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation | Q40506646 | ||
Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function | Q40651409 | ||
Antiarrhythmic drugs and torsade de pointes | Q40807714 | ||
Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets. | Q40978901 | ||
Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms | Q40990740 | ||
Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism | Q41015991 | ||
Mutagenic analysis of platelet thromboxane receptor cysteines. Roles in ligand binding and receptor-effector coupling | Q41216013 | ||
Further evidence that thromboxane exacerbates arrhythmias: effects of UK38485 during coronary artery occlusion and reperfusion in anaesthetized greyhounds | Q41572758 | ||
14-3-3zeta interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase | Q42170095 | ||
Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3′-pyridinylmethyl)benzofuran-2-carboxylate | Q42246687 | ||
Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin | Q42472257 | ||
Labeling of human platelet plasma membrane thromboxane A2/prostaglandin H2 receptors using SQB, a novel biotinylated receptor probe | Q42554632 | ||
Functional comparison of the antagonistic properties of some Angiotensin II type 1 receptor blockers on the contraction elicited by Angiotensin II and thromboxane A2 on human saphenous veins. | Q42602291 | ||
Glybenclamide: an antidiabetic with in vivo antithrombotic activity | Q42880731 | ||
Activity of a novel dual thromboxane A(2)receptor antagonist and thromboxane synthase inhibitor (BM-573) on platelet function and isolated smooth muscles | Q43730032 | ||
Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling | Q43860082 | ||
Angiotensin II AT1 receptor antagonists inhibit platelet adhesion and aggregation by nitric oxide release | Q44167942 | ||
Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function | Q44284991 | ||
Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach | Q44292843 | ||
TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets | Q44545094 | ||
Characterization of a new compound, S-145, as a specific TXA2 receptor antagonist in platelets | Q44730150 | ||
Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor | Q44786762 | ||
Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: alternative role in G protein-coupled receptor signaling. | Q44960382 | ||
Factor XI interacts with the leucine-rich repeats of glycoprotein Ibalpha on the activated platelet | Q45064186 | ||
Effects of KP-496, a novel dual antagonist for cysteinyl leukotriene receptor 1 and thromboxane A2 receptor, on Sephadex-induced airway inflammation in rats. | Q45989071 | ||
Antithrombotic and antiplatelet activities of fenofibrate, a lipid-lowering drug | Q46061444 | ||
A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids | Q46307406 | ||
Effect of inhibitors of arachidonic acid conversion in platelets on thrombin-fibrinogen interaction and thrombin tolerance | Q46472175 | ||
The Lsc RhoGEF mediates signaling from thromboxane A2 to actin polymerization and apoptosis in thymocytes | Q46482145 | ||
The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies. | Q46566202 | ||
Coupling interaction between thromboxane A2 receptor and alpha-13 subunit of guanine nucleotide-binding protein | Q46741746 | ||
Gbeta 5gamma 2 is a highly selective activator of phospholipid-dependent enzymes. | Q52972449 | ||
P433 | issue | 3 | |
P304 | page(s) | 248-259 | |
P577 | publication date | 2011-11-07 | |
P1433 | published in | Journal of Cardiovascular Pharmacology and Therapeutics | Q1855644 |
P1476 | title | Thromboxane A2 receptor: biology and function of a peculiar receptor that remains resistant for therapeutic targeting | |
P478 | volume | 17 |
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