Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin.

scientific article published on 30 March 2009

Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4137/IJTR.S1022
P932PMC publication ID3195225
P698PubMed publication ID22084581

P2093author name stringKazuhiro Nakamura
Hiroyuki Hasegawa
P2860cites workTetrahydrobiopterin biosynthesis, regeneration and functionsQ24531994
TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESISQ28201039
A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERSQ28201452
Disorders of tetrahydrobiopterin metabolism and their treatmentQ28217123
Enzymic Studies on the Biosynthesis of Serotonin in Mammalian BrainQ28251462
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory regionQ28297391
Platelet-derived serotonin mediates liver regenerationQ28306257
Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell lineQ28568914
Role of a serotonin precursor in development of gut microvilliQ30493815
Reduced availability of brain amines during critical phases of postnatal development in a genetic mouse model of cognitive delayQ33337644
Role of serotonin in the immune system and in neuroimmune interactionsQ33542079
Immunohistochemical localization of tryptophan hydroxylase in the human and rat gastrointestinal tractsQ33869202
A new cofactor required for the enzymatic conversion of phenylalanine to tyrosineQ34243369
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule releaseQ34286484
Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects.Q34633011
Monoamine transporters: from genes to behaviorQ34931139
Delivery of exogenous tetrahydrobiopterin (BH4) to cells of target organs: role of salvage pathway and uptake of its precursor in effective elevation of tissue BH4.Q36300275
Inherited disorders affecting dopamine and serotonin: critical neurotransmitters derived from aromatic amino acidsQ36826842
Developmental role of tryptophan hydroxylase in the nervous systemQ36829277
Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular diseaseQ36842798
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterinQ39382909
Regulation of serotonin synthesisQ39955154
Distinctive iron requirement of tryptophan 5-monooxygenase: TPH1 requires dissociable ferrous ironQ40368891
The spectrum of behaviors influenced by serotoninQ40847700
Rapid turnover of tryptophan hydroxylase is driven by proteasomes in RBL2H3 cells, a serotonin producing mast cell lineQ40891680
Iron dependence of tryptophan hydroxylase activity in RBL2H3 cells and its manipulation by chelatorsQ40958695
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages.Q41758509
Serotonin upregulates the activity of phagocytosis through 5-HT1A receptorsQ41770341
The biosynthesis of 5-hydroxytryptamine in brainQ42073256
A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cellsQ42127557
Serotonin protects NK cells against oxidatively induced functional inhibition and apoptosis.Q43660609
Treatable neurotransmitter deficiency in mild phenylketonuriaQ43734091
5-Hydroxytryptophan (5-HTP)-immunoreactive neurons in the rat brain tissueQ43829839
5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout miceQ43964308
5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to the nucleusQ44677515
Biosynthesis of 5-hydroxytryptophan and 5-hydroxytryptamine from tryptophan by neoplastic mouse mast cellsQ44694794
The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine releaseQ44885056
Tetrahydrobiopterin uptake in supplemental administration: elevation of tissue tetrahydrobiopterin in mice following uptake of the exogenously oxidized product 7,8-dihydrobiopterin and subsequent reduction by an anti-folate-sensitive processQ45092363
Tetrahydrobiopterin in intestinal lumen: its absorption and secretion in the small intestine and the elimination in the large intestineQ46230533
Transcellular relocation of tetrahydrobiopterin across Caco-2 cells: a model study of tetrahydrobiopterin absorption through epithelial cells of intestinal mucosaQ46268494
Cellular uptake of sepiapterin and push-pull accumulation of tetrahydrobiopterinQ46568433
Accumulated BH4 in mouse liver caused by administration of either 6R- or 6SBH4 consisted solely of the 6R-diastereomer: evidence of oxidation to BH2 and enzymic reductionQ46705760
Cellular accumulation of tetrahydrobiopterin following its administration is mediated by two different processes; direct uptake and indirect uptake mediated by a methotrexate-sensitive processQ46705778
First characterization of 5-hydroxytryptophan in rat brain by using specific antibodiesQ48183032
Effect of reserpine on 5-hydroxytryptophan (5HTP)-immunoreactive neurons in the rat brainQ48215365
Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductaseQ48671468
The effects of high phenylalanine concentrations on serotinin and catecholamine metabolism in the human brainQ48710446
Tryptophan hydroxylation: measurement in pineal gland, brainstem, and carcinoid tumor.Q51219894
Abnormalities of serotonin metabolism and their relation to symptoms in untreated celiac disease.Q51495897
Serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors.Q54611180
Estimation of the rate of tryptophan hydroxylation in vivo: a sensitive microassay in discrete rat brain nucleiQ70523262
Biosynthesis of pteridines in the tadpole of the bullfrog, Rana catesbeianaQ71649424
Measurement of neurotransmitter metabolites in the cerebrospinal fluid of phenylketonuric patients under dietary treatmentQ74006257
Differential distribution of serotonin and tryptophan hydroxylase in the human gastrointestinal tractQ77806560
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
P304page(s)37-43
P577publication date2009-03-30
P1433published inInternational Journal of Tryptophan ResearchQ27722446
P1476titleProduction and Peripheral Roles of 5-HTP, a Precursor of Serotonin
P478volume2