Pharmacodynamics of TNF-α inhibitors in psoriasis

scientific article published on July 2011

Pharmacodynamics of TNF-α inhibitors in psoriasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1586/ECP.11.28
P698PubMed publication ID22114860

P2093author name stringChristina Antoniou
Alexander J Stratigos
Petros P Sfikakis
Theognosia Vergou
Aikaterini-Evangelia Moustou
P2860cites workThe first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directionsQ37696090
Cytokine modulation of adhesion molecules in the regulation of immunologic cytotoxicity of epidermal targetsQ38010159
Functional comparisons of different tumour necrosis factor receptor/IgG fusion proteinsQ38289674
Epidermal CD8+ T cells in chronic plaque psoriasis are Tc1 cells producing heterogeneous levels of interferon-gammaQ40802615
A novel p75TNF receptor isoform mediating NFkappa B activationQ40816200
Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functionsQ41355139
Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanerceptQ42479845
Binding characteristics of tumor necrosis factor receptor-Fc fusion proteins vs anti-tumor necrosis factor mAbsQ46143952
CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.Q52918582
Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor.Q53787487
Binding and Functional Comparisons of Two Types of Tumor Necrosis Factor AntagonistsQ56864876
Autoimmune Diseases Induced by TNF-Targeted TherapiesQ56907567
The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the gamesQ24683018
Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trialQ28202251
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptorQ28610826
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseasesQ29547555
Characterization of noncovalent complexes of recombinant human monoclonal antibody and antigen using cation exchange, size exclusion chromatography, and BIAcoreQ30715893
Infliximab for severe, treatment-resistant psoriasis: a prospective, open-label studyQ33371653
A domain in TNF receptors that mediates ligand-independent receptor assembly and signalingQ33907802
Construction and initial characterization of a mouse-human chimeric anti-TNF antibodyQ34060890
Keratins (Kl6 and Kl7) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitroQ34296920
The immunologic basis for the treatment of psoriasis with new biologic agentsQ34470558
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiatQ34505900
The TNF-TNF receptor systemQ35009296
Early effects of tumour necrosis factor alpha blockade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritisQ35554321
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factorQ35739690
Biology of tumor necrosis factor-alpha- implications for psoriasisQ35746601
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responsesQ36294340
Tumor necrosis factor antagonists: different kinetics and/or mechanisms of action may explain differences in the risk for developing granulomatous infectionQ36555176
Interleukin-12, interleukin-23, and psoriasis: current prospectsQ36913621
Tumor necrosis factor antagonist mechanisms of action: a comprehensive reviewQ37043901
Cutaneous side effects of anti-tumor necrosis factor biologic therapy: a clinical reviewQ37560336
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpharmacodynamicsQ725307
TNFQ18032037
P304page(s)515-523
P577publication date2011-07-01
P1433published inExpert Review of Clinical PharmacologyQ15793519
P1476titlePharmacodynamics of TNF-α inhibitors in psoriasis
P478volume4

Reverse relations

cites work (P2860)
Q34504431Expression of lymphatic markers and lymphatic growth factors in psoriasis before and after anti-TNF treatment
Q54214331The Use and Safety of TNF Inhibitors during Pregnancy in Women with Psoriasis: A Review.

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