The pig: a model for human infectious diseases

scientific article published on 05 December 2011

The pig: a model for human infectious diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TIM.2011.11.002
P698PubMed publication ID22153753
P5875ResearchGate publication ID51863962

P50authorLinda SaifQ20502360
Artur SummerfieldQ38328813
Hans J NauwynckQ74988006
Volker GerdtsQ96650456
P2093author name stringFrançois Meurens
P2860cites workCrystal Structure of Swine Major Histocompatibility Complex Class I SLA-1*0401 and Identification of 2009 Pandemic Swine-Origin Influenza A H1N1 Virus Cytotoxic T Lymphocyte Epitope PeptidesQ27673392
Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosaQ28742559
Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigsQ28748169
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional propertiesQ29547848
Antimicrobial host defense peptides in an arteriviral infection: differential peptide expression and virus inactivation.Q30378853
Adaptive strategies of the influenza virus polymerase for replication in humansQ30383307
Swine influenza H1N1 virus induces acute inflammatory immune responses in pig lungs: a potential animal model for human H1N1 influenza virusQ30392760
2009 pandemic H1N1 influenza virus causes disease and upregulation of genes related to inflammatory and immune responses, cell death, and lipid metabolism in pigsQ30406831
Genetic resources, genome mapping and evolutionary genomics of the pig (Sus scrofa)Q33279940
Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technologyQ33490622
Animal models for gastric Helicobacter immunology and vaccine studiesQ33667083
The piglet as a model for B cell and immune system developmentQ33687288
Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distributionQ33692187
Interferon alpha induces establishment of alphaherpesvirus latency in sensory neurons in vitroQ33711923
Infection of newborn piglets with Bordetella pertussis: a new model for pertussisQ33788175
Light microscopic, electron microscopic, and immunohistochemical comparison of Bama minipig (Sus scrofa domestica) and human skinQ33791171
Human chromosome 3 and pig chromosome 13 show complete synteny conservation but extensive gene-order differencesQ38499398
Human noroviruses in swine and cattleQ39255240
Transplantation in miniature swine. I. Fixation of the major histocompatibility complexQ39797710
A new dynamic porcine model of meningococcal shockQ40007131
Infection with Bordetella parapertussis but not Bordetella pertussis causes pertussis-like disease in older pigsQ40417195
Pathogenesis of granulocytopenia and bone marrow atrophy during classical swine fever involves apoptosis and necrosis of uninfected cellsQ40619394
The gnotobiotic piglet as a model for studies of disease pathogenesis and immunity to human rotaviruses.Q41335263
Pig genome sequence--analysis and publication strategyQ42564114
Antibody repertoire development in fetal and neonatal pigs. VII. Characterization of the preimmune kappa light chain repertoireQ42641152
A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosaQ42728621
Immunodeficiency in young pigsQ44395934
Villous atrophy, crypt hyperplasia, cellular infiltration, and impaired glucose-Na absorption in enteric cryptosporidiosis of pigsQ44859159
Correlations between lung proinflammatory cytokine levels, virus replication, and disease after swine influenza virus challenge of vaccination-immune pigsQ45729636
Inducible nitric oxide synthase expression in porcine immune cellsQ48012755
Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigsQ48055540
The use of pigs in neuroscience: modeling brain disordersQ48195971
Bronchoalveolar interferon-alpha, tumor necrosis factor-alpha, interleukin-1, and inflammation during acute influenza in pigs: a possible model for humans?Q49091133
Cytokines and acute phase proteins associated with acute swine influenza infection in pigs.Q49114204
Special issue on porcine immunology: An introduction from the guest editorQ56775441
Effect of Human Rotavirus Vaccine on Severe Diarrhea in African InfantsQ57530944
A pig model of Acanthamoeba keratitis: transmission via contaminated contact lensesQ67727867
Staphylococcal wound infection in the pig: Part I. CourseQ69734107
Pathogenesis of an attenuated and a virulent strain of group A human rotavirus in neonatal gnotobiotic pigsQ71398200
[Expression of Toll-like receptors in mononuclear cells from children with acute rotavirus diarrhea]Q80148041
Porcine regulatory T cells: mechanisms and T-cell targets of suppressionQ84002552
A non-traumatic Staphylococcus aureus osteomyelitis model in pigsQ84423783
Immune components in porcine mammary secretionsQ34052193
Specific-pathogen-free pigs as an animal model for studying Chlamydia trachomatis genital infection.Q34194846
Worldwide phylogeography of wild boar reveals multiple centers of pig domesticationQ34402008
Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig modelsQ34551504
Maternal immunity provides protection against pertussis in newborn pigletsQ34601948
In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome but rewardingQ34693331
A review of porcine tonsils in immunity and diseaseQ35768087
Differential interaction of Escherichia coli heat-labile toxin and cholera toxin with pig intestinal brush border glycoproteins depending on their ABH and related blood group antigenic determinantsQ35777241
Binding patterns of human norovirus-like particles to buccal and intestinal tissues of gnotobiotic pigs in relation to A/H histo-blood group antigen expressionQ35785043
Exotic emerging viral diseases: progress and challengesQ35971398
Porcine noroviruses related to human norovirusesQ36009523
Altered pathogenesis of porcine respiratory coronavirus in pigs due to immunosuppressive effects of dexamethasone: implications for corticosteroid use in treatment of severe acute respiratory syndrome coronavirusQ36315144
Mendelian resistance to human norovirus infectionsQ36594372
Selected physiologic compatibilities and incompatibilities between human and porcine organ systemsQ36632325
Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17.Q36643123
Infection immunity of piglets to either VP3 or VP7 outer capsid protein confers resistance to challenge with a virulent rotavirus bearing the corresponding antigenQ36875550
Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs.Q36953220
The isolator piglet: a model for studying the development of adaptive immunityQ36961026
The benefits of using diverse animal models for studying pertussis.Q36962817
PB2 protein of a highly pathogenic avian influenza virus strain A/chicken/Yamaguchi/7/2004 (H5N1) determines its replication potential in pigsQ37099830
Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs.Q37121858
A pig model of acute Staphylococcus aureus induced pyemiaQ37154864
The porcine dendritic cell familyQ37201048
Membrane markers of the immune cells in swine: an updateQ37220576
Species specialization in cytokine biology: is interleukin-4 central to the T(H)1-T(H)2 paradigm in swine?Q37257481
Humoral and cellular factors of maternal immunity in swine.Q37257486
Dendritic cells--at the front-line of pathogen attackQ37335629
Animal models of henipavirus infection: a reviewQ37351362
Animal models of ventilator-associated pneumoniaQ37360866
Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotidesQ37375206
Transgenic pigs as models for translational biomedical researchQ37719307
The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and diseaseQ37828326
Pathogenetic elements of hepatitis E and animal models of HEV infectionQ37854151
Swine as models in biomedical research and toxicology testingQ37858258
P433issue1
P921main subjectpigQ787
P304page(s)50-57
P577publication date2011-12-05
P1433published inTrends in MicrobiologyQ15265732
P1476titleThe pig: a model for human infectious diseases
P478volume20

Reverse relations

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Q30396591Pigs with Severe Combined Immunodeficiency Are Impaired in Controlling Influenza A Virus Infection
Q36045264Pneumococcal colonization and invasive disease studied in a porcine model
Q64275885Polysaccharides Prevent Palmitic Acid-Evoked Apoptosis and Autophagy in Intestinal Porcine Epithelial Cell Line via Restoration of Mitochondrial Function and Regulation of MAPK and AMPK/Akt/mTOR Signaling Pathway
Q55715244Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus.
Q40048525Porcine B Cell Subset Responses to Toll-like Receptor Ligands
Q91971665Porcine Invariant Natural Killer T Cells: Functional Profiling and Dynamics in Steady State and Viral Infections
Q42700525Porcine Models of Biofilm Infections with Focus on Pathomorphology
Q64102628Porcine Models of Pancreatic Cancer
Q56797673Porcine colon explants in the study of innate immune response to Entamoeba histolytica
Q38492778Porcine models of cutaneous wound healing
Q37840129Porcine retinal cell line VIDO R1 and Chlamydia suis to modelize ocular chlamydiosis
Q57473582Porcine signal regulatory protein alpha binds to human CD47 to inhibit phagocytosis: Implications for human hematopoietic stem cell transplantation into severe combined immunodeficient pigs
Q51710324Postnatal development of lung T lymphocytes in a porcine model.
Q91866917Potential relevance of pig gut content transplantation for production and research
Q93024663Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery
Q28554656Preclinical Study of Single-Dose Moxidectin, a New Oral Treatment for Scabies: Efficacy, Safety, and Pharmacokinetics Compared to Two-Dose Ivermectin in a Porcine Model
Q90974920Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
Q34404931Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs.
Q53408298Psychosocial Stress and Immunity-What Can We Learn From Pig Studies?
Q52725593Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.
Q40619005Resequencing diverse Chinese indigenous breeds to enrich the map of genomic variations in swine
Q37554997Respiratory viral infection in neonatal piglets causes marked microglia activation in the hippocampus and deficits in spatial learning
Q57619470Review: Are we using probiotics correctly in post-weaning piglets?
Q92219353Rock Inhibitor Y-27632 Enables Feeder-Free, Unlimited Expansion of Sus scrofa domesticus Swine Airway Stem Cells to Facilitate Respiratory Research
Q30379214Role of Substitutions in the Hemagglutinin in the Emergence of the 1968 Pandemic Influenza Virus.
Q92968346Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development
Q39375137Roles of amino acids in preventing and treating intestinal diseases: recent studies with pig models
Q94402935SCID pigs: An emerging large animal NK model
Q38065534SOCS proteins in infectious diseases of mammals.
Q40067462Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine.
Q33685480Scabies mites alter the skin microbiome and promote growth of opportunistic pathogens in a porcine model
Q44577477Select human milk oligosaccharides directly modulate peripheral blood mononuclear cells isolated from 10-d-old pigs
Q33886345Selection of Reference Genes for Gene Expression Studies in Porcine Whole Blood and Peripheral Blood Mononuclear Cells under Polyinosinic:Polycytidylic Acid Stimulation
Q93075496Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
Q92538352Sexual Dimorphism in Immune Development and in Response to Nutritional Intervention in Neonatal Piglets
Q104800025Skin Immune Cell Characterization in Juvenile and Adult Göttingen Minipigs
Q38848091Small molecule and RNAi induced phenotype transition of expanded and primary colonic epithelial cells
Q55437841Standardized Preparation for Fecal Microbiota Transplantation in Pigs.
Q35609398Staphylococcus aureus induces hypoxia and cellular damage in porcine dermal explants
Q34436905Strategies to improve drug development for sepsis
Q36427930Structural Variant Detection by Large-scale Sequencing Reveals New Evolutionary Evidence on Breed Divergence between Chinese and European Pigs
Q78177266Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.
Q90611115Successful development of methodology for detection of hapten-specific contact hypersensitivity (CHS) memory in swine
Q92860063Successional Dynamics in the Gut Microbiome Determine the Success of Clostridium difficile Infection in Adult Pig Models
Q35635820Swine as a model for influenza A virus infection and immunity
Q58779504Symptoms of systemic lupus erythematosus are diagnosed in leptin transgenic pigs
Q40986565T Cell Lymphoma and Leukemia in Severe Combined Immunodeficiency Pigs following Bone Marrow Transplantation: A Case Report.
Q64238019T and B Cell Immune Responses to Influenza Viruses in Pigs
Q27322386TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes
Q38392001TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development
Q30811506Techniques for thoracic duct cannulation without thoracotomy in piglets.
Q47239063Testing the Use of Pigs as Human Proxies in Decomposition Studies
Q92151381The African strain of Zika virus causes more severe in utero infection than Asian strain in a porcine fetal transmission model
Q113697804The Complex Interactions Between Rotavirus and the Gut Microbiota
Q90379866The Composition of Circulating Leukocytes Varies With Age and Melanoma Onset in the MeLiM Pig Biomedical Model
Q92106992The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs
Q58797218The Intestinal Roundworm Releases Antimicrobial Factors Which Interfere With Bacterial Growth and Biofilm Formation
Q47128290The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery
Q41526718The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform
Q36674401The Pig PeptideAtlas: A resource for systems biology in animal production and biomedicine.
Q40406423The domestic pig as a potential model for Borrelia skin infection.
Q96588894The domestic pig as human-relevant large animal model to study adaptive anti-fungal immune responses against airborne Aspergillus fumigatus
Q39210061The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine
Q27004696The impact of Fusarium mycotoxins on human and animal host susceptibility to infectious diseases
Q55517984The inflammatory response and neuronal injury in Streptococcus suis meningitis.
Q40096111The minipig as an animal model to study Mycobacterium tuberculosis infection and natural transmission.
Q36382772The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases.
Q38202723The porcine innate immune system: an update
Q38613788The porcine translational research database: a manually curated, genomics and proteomics-based research resource.
Q40924827The respiratory DC/macrophage network at steady-state and upon influenza infection in the swine biomedical model.
Q59354383The tree shrew as a model for infectious diseases research
Q35824726The vaginal microbiome is stable in prepubertal and sexually mature Ellegaard Göttingen Minipigs throughout an estrous cycle
Q34113617Towards the establishment of a porcine model to study human amebiasis
Q36867885Transcriptomic Analysis Identifies Candidate Genes and Gene Sets Controlling the Response of Porcine Peripheral Blood Mononuclear Cells to Poly I:C Stimulation
Q35907196Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model
Q91899947Ungulates as model systems for the study of disease processes in natural populations
Q61800188Vaccine Development for Nipah Virus Infection in Pigs
Q34976021Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease
Q45324179Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs
Q43046870Zika Virus Causes Persistent Infection in Porcine Conceptuses and may Impair Health in Offspring
Q41433006β2-microglobulin gene duplication in cetartiodactyla remains intact only in pigs and possibly confers selective advantage to the species