Use of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical procedures

scientific article published on 27 December 2011

Use of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical procedures is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1345/APH.1Q383
P698PubMed publication ID22202494

P2093author name stringHeather J Ipema
Maria G Tanzi
P2860cites workPharmacological strategies to decrease transfusion requirements in patients undergoing surgeryQ28193941
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Intranasal tranexamic acid treatment for severe epistaxis in hereditary hemorrhagic telangiectasiaQ32084543
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Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplastyQ35355159
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Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?Q36634947
Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysisQ36709677
Pharmacologic methods to reduce perioperative bleedingQ37095552
Can local application of Tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trialQ37253019
Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: a systematic review of randomized trialsQ37325204
High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients.Q37649234
Lessons from aprotinin: is the routine use and inconsistent dosing of tranexamic acid prudent? Meta-analysis of randomised and large matched observational studiesQ37684512
Re-evaluation of the role of antifibrinolytic therapy with lysine analogs during cardiac surgery in the post aprotinin eraQ37794607
Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients.Q37802652
Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: a systematic review and meta-analysis.Q37813267
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Topical use of tranexamic acid to control perioperative local bleeding in gynaecology patients with clotting disorders: two casesQ39432143
Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysisQ42420172
Effect of topical tranexamic acid in open heart surgeryQ42678877
Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial.Q42837549
Effect of topical aprotinin on early postoperative bleeding and ICU stay after coronary artery bypass graft surgeriesQ43266537
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Seizures after open heart surgery: comparison of ε-aminocaproic acid and tranexamic acidQ44682665
Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized prospective clinical studyQ44685522
Topical aminocaproic acid in the treatment of traumatic hyphemaQ45106769
Effect of local antifibrinolytic treatment with tranexamic acid in hemophiliacs undergoing oral surgeryQ45264894
Effectiveness in controlling haemorrhage after dental scaling in people with haemophilia by using tranexamic acid mouthwashQ45270351
Primary wound closure in haemophiliacs undergoing dental extractionsQ45883930
The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patientsQ46237528
Perioperative renal outcome in cardiac surgical patients with preoperative renal dysfunction: aprotinin versus epsilon aminocaproic acidQ46772191
Effects of topical antifibrinolytics in endoscopic sinus surgery: a pilot randomized controlled trialQ46803855
A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery.Q46988001
Tranexamic acid applied topically to achieve haemostasis.Q51395033
Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.Q51619886
Topical aprotinin in cardiac operations.Q52372487
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttranexamic acidQ418666
P304page(s)97-107
P577publication date2011-12-27
P1433published inAnnals of PharmacotherapyQ4767858
P1476titleUse of topical tranexamic acid or aminocaproic acid to prevent bleeding after major surgical procedures
P478volume46

Reverse relations

cites work (P2860)
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Q91236931Immunohistochemical Grading of Epidural Fibrosis with CD105 Antibody
Q90168870Magnetically controlled protein nanocontainers as a drug depot for the hemostatic agent
Q38367687One step closer to sparing total blood loss and transfusion rate in total knee arthroplasty: a meta-analysis of different methods of tranexamic acid administration
Q85777100Onsets of complications and revisions are not increased after simultaneous bilateral unicompartmental knee arthroplasty in comparison with unilateral procedures
Q45968801Peri-operative blood-loss after total hip arthroplasty can be significantly reduced with topical application of epsilon-aminocaproic acid.
Q36143953Randomized clinical trial of topical tranexamic acid after reduction mammoplasty
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Q26751278Systemic and Topical Use of Tranexamic Acid in Spinal Surgery: A Systematic Review
Q47917753The optimal protocol to reduce blood loss and blood transfusion after unilateral total knee replacement: Low-dose IA-TXA plus 30-min drain clamping versus drainage clamping for the first 3 h without IA-TXA.
Q35926609Thromboelastography: A Practice Summary for Nurse Practitioners Treating Hemorrhage
Q36273712Topical versus intravenous tranexamic acid in total knee arthroplasty
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Q47197183Tranexamic acid reduces surgical bleeding: does one size fit all?
Q90662028Use of Topical Tranexamic Acid to Reduce Blood Loss in Single-Level Transforaminal Lumbar Interbody Fusion

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