PAS kinase: integrating nutrient sensing with nutrient partitioning

scientific article published on 08 January 2012

PAS kinase: integrating nutrient sensing with nutrient partitioning is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SEMCDB.2011.12.007
P932PMC publication ID3331943
P698PubMed publication ID22245833
P5875ResearchGate publication ID221748127

P2093author name stringJared Rutter
Caleb M Cardon
P2860cites workmTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machineryQ24302549
Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylationQ24302557
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveQ24306328
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth controlQ24314363
Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiaeQ24537557
PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinaseQ24556167
Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucoseQ24561550
mTOR: from growth signal integration to cancer, diabetes and ageingQ24633662
Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulationQ27639771
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factorsQ27929794
Cbk1 regulation of the RNA-binding protein Ssd1 integrates cell fate with translational controlQ27931205
TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.Q27933425
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarizationQ27933591
Genetic and Biochemical Characterization of the UGP1 Gene Encoding the UDP‐Glucose Pyrophosphorylase from Saccharomyces cerevisiaeQ27934217
The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetryQ27935019
Dynamic responses of reserve carbohydrate metabolism under carbon and nitrogen limitations in Saccharomyces cerevisiaeQ74605078
The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeletonQ77540852
Coordinate regulation of sugar flux and translation by PAS kinaseQ27935306
Regulation of glucose partitioning by PAS kinase and Ugp1 phosphorylationQ27936308
Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase.Q27936453
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeastQ27937613
A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.Q27938852
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.Q27938906
Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translationQ28378802
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastomaQ28472048
PAS kinase is required for normal cellular energy balanceQ28506039
Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretionQ28511272
Active and inactive protein kinases: structural basis for regulationQ29616320
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progressionQ29616821
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolismQ29617261
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energyQ29618101
Roles of the AMP-activated/SNF1 protein kinase family in the response to cellular stressQ33596238
PAS-A domain of phosphorelay sensor kinase A: a catalytic ATP-binding domain involved in the initiation of development in Bacillus subtilisQ33953089
Characterization of yeast translation initiation factor 1A and cloning of its essential geneQ34719928
Structure and signaling mechanism of Per-ARNT-Sim domainsQ35008317
Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion.Q35626071
Subunit and domain requirements for adenylate-mediated protection of Snf1 kinase activation loop from dephosphorylationQ35639796
TOR2 is required for organization of the actin cytoskeleton in yeastQ35930168
Isolation and expression analysis of two yeast regulatory genes involved in the derepression of glucose-repressible enzymesQ36288213
The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiaeQ36468946
Release of two Saccharomyces cerevisiae cytochrome genes, COX6 and CYC1, from glucose repression requires the SNF1 and SSN6 gene productsQ36722704
Glucose Represses Transcription of Saccharomyces cerevisiae Nuclear Genes That Encode Mitochondrial ComponentsQ36944543
Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.Q37317469
LKB1 and AMP-activated protein kinase control of mTOR signalling and growthQ37383513
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer.Q37602774
Mechanisms of mTOR inhibitor resistance in cancer therapyQ37872670
AMPK and mTOR in cellular energy homeostasis and drug targetsQ37948152
Heme-binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms.Q38291000
The oxygen sensor protein, FixL, of Rhizobium meliloti. Role of histidine residues in heme binding, phosphorylation, and signal transductionQ38297765
Yeast PAS kinase coordinates glucose partitioning in response to metabolic and cell integrity signalingQ40811900
AMPK and autophagy get connected.Q41874222
PAS kinase promotes cell survival and growth through activation of Rho1.Q41968750
Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptorQ42111298
AMPK and Raptor: matching cell growth to energy supply.Q45902079
Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratioQ71824307
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)626-630
P577publication date2012-01-08
P1433published inSeminars in Cell & Developmental BiologyQ14330411
P1476titlePAS kinase: integrating nutrient sensing with nutrient partitioning
P478volume23

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cites work (P2860)
Q34582206A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Q33881412A comprehensive protein-protein interactome for yeast PAS kinase 1 reveals direct inhibition of respiration through the phosphorylation of Cbf1.
Q43210750Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG2 cells
Q35027599PAS kinase is activated by direct SNF1-dependent phosphorylation and mediates inhibition of TORC1 through the phosphorylation and activation of Pbp1
Q60953856Per-Arnt-Sim Kinase (PASK) Deficiency Increases Cellular Respiration on a Standard Diet and Decreases Liver Triglyceride Accumulation on a Western High-Fat High-Sugar Diet
Q28085060Per-Arnt-Sim Kinase (PASK): An Emerging Regulator of Mammalian Glucose and Lipid Metabolism
Q37112742Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3β in pancreatic β-cells
Q35894983Postprandial Responses to Lipid and Carbohydrate Ingestion in Repeated Subcutaneous Adipose Tissue Biopsies in Healthy Adults.
Q58087933The Regulation of Cbf1 by PAS Kinase Is a Pivotal Control Point for Lipogenesis vs. Respiration in Saccharomyces cerevisiae.
Q37630962The hijacking of cellular signaling and the diabetes epidemic: mechanisms of environmental disruption of insulin action and glucose homeostasis

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