The SDF-1/CXCR4 axis in stem cell preconditioning

scientific article published on 26 March 2012

The SDF-1/CXCR4 axis in stem cell preconditioning is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CVR/CVS132
P698PubMed publication ID22451511
P5875ResearchGate publication ID221982977

P2093author name stringMaurizio C Capogrossi
Monica Napolitano
Chiara Cencioni
P2860cites workControlled release of stromal cell-derived factor-1 alpha in situ increases c-kit+ cell homing to the infarcted heart.Q50998107
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CXCR4+/FLK-1+ biomarkers select a cardiopoietic lineage from embryonic stem cells.Q51961075
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Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury.Q54693969
AngiogenesisQ56689455
SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor CellsQ56921714
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cellsQ58816342
Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cellsQ24603371
Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2Q24648959
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor developmentQ24676591
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)Q24677007
CXCR7 functions as a scavenger for CXCL12 and CXCL11Q27334618
Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI)Q28193273
Acidification prevents endothelial cell apoptosis by Axl activationQ28205422
Human chemokines: an updateQ28237635
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancerQ28259852
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytesQ28267757
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardiumQ28304462
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tractQ28504884
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.Q28511299
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar developmentQ28512895
Molecular mechanisms and clinical applications of angiogenesisQ29547314
Basic and therapeutic aspects of angiogenesisQ29615219
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1Q29615241
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Q29616092
Human adipose tissue is a source of multipotent stem cellsQ29617385
Marrow stromal cells as stem cells for nonhematopoietic tissuesQ29618770
Ex vivo delivered stromal cell-derived factor-1alpha promotes stem cell homing and induces angiomyogenesis in the infarcted myocardiumQ30486444
Revascularization in the rabbit hindlimb: dissociation between capillary sprouting and arteriogenesisQ31882403
Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapyQ33257976
Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1.Q33280490
Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivoQ33283525
Stem cell therapy: pieces of the puzzleQ33348580
Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potentialQ33649297
Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injuryQ33745154
The late phase of preconditioningQ33926118
Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cellsQ34009778
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathwayQ39946864
Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-kappaB on HEI-OC1 cells.Q40417893
HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generationQ40439908
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.Q40633683
Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles.Q40648297
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell functionQ40736018
Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cellsQ40839710
The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flowQ40857641
Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression.Q40899767
The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathwaysQ41012131
Rate of rise of myocardial PCO2 during early myocardial ischemia in the dogQ41675360
Early expression of angiogenesis factors in acute myocardial ischemia and infarctionQ41722694
Generation of protons by metabolic processes in heart cellsQ41761819
Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarctionQ41871395
Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heartQ42507068
Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCsQ42876765
Cardiac progenitor cells: the revolution continuesQ43145194
Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) miceQ43600842
Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery diseaseQ43664648
Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokersQ44932451
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthaseQ45091743
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemiaQ45871892
Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulationQ45874391
Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarctionQ45882845
Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis.Q45966730
Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumoniaQ46301623
Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brainQ46566592
Inflammatory receptors and pathways in human NT2-N neurons during hypoxia and reoxygenation. Impact of acidosisQ46576262
SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cellsQ46740027
Effect of catheter-based transendocardial delivery of stromal cell-derived factor 1alpha on left ventricular function and perfusion in a porcine model of myocardial infarctionQ46871321
The chemokine SDF1a coordinates tissue migration through the spatially restricted activation of Cxcr7 and Cxcr4bQ47073842
Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovascQ47590872
Increased expression of CXCR4 and integrin alphaM in hypoxia-preconditioned cells contributes to improved cell retention and angiogenic potencyQ47881673
Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis.Q50640546
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1Q34052670
Protective responses in the ischemic myocardiumQ34052677
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy.Q34228118
Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusionQ34305822
Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axisQ34418159
Acidosis during early reperfusion prevents myocardial stunning in perfused ferret heartsQ34562428
SDF-1α secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7Q35009602
VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heartQ35114758
Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrilsQ35169533
Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein inductionQ35208828
Impaired CXCR4 expression and cell engraftment of bone marrow-derived cells from aged atherogenic miceQ35501916
Mesenchymal stem cells and their potential as cardiac therapeuticsQ35830869
Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissueQ36122793
Regulation of the chemokine receptor CXCR4 by hypoxiaQ36371842
Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cellsQ36402579
Formation of large coronary arteries by cardiac progenitor cellsQ36446471
SDF-1alpha-mediated tissue repair by stem cells: a promising tool in cardiovascular medicine?Q36483554
Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells.Q36502835
Chemokines in hematopoiesisQ37016789
Homing and engraftment of progenitor cells: a prerequisite for cell therapyQ37096297
CXCR4 signaling in the regulation of stem cell migration and developmentQ37174923
Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expressionQ37372976
Acidic preconditioning protects endothelial cells against apoptosis through p38- and Akt-dependent Bcl-xL overexpression.Q37376788
Acidic pre-conditioning suppresses apoptosis and increases expression of Bcl-xL in coronary endothelial cells under simulated ischaemiaQ37568721
Role of the SDF-1-CXCR4 axis in stem cell-based therapies for ischemic cardiomyopathyQ37687409
Homing of progenitor cells to ischemic tissuesQ37784827
SDF-1α as a therapeutic stem cell homing factor in myocardial infarctionQ37802012
CXCL12 and CXCR4 in bone marrow physiologyQ37810099
Stromal-derived factor-1/CXCR4 signaling: indispensable role in homing and engraftment of hematopoietic stem cells in bone marrowQ37824153
Stromal cell-derived factor-1 (SDF-1): homing factor for engineered regenerative medicine.Q37827159
Hematopoietic stem cell homing to injured tissues.Q37845721
Mobilization of stem and progenitor cells in cardiovascular diseasesQ37905521
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidaseQ38299258
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligandsQ39819165
P433issue3
P304page(s)400-407
P577publication date2012-03-26
P1433published inCardiovascular ResearchQ4642329
P1476titleThe SDF-1/CXCR4 axis in stem cell preconditioning
P478volume94

Reverse relations

cites work (P2860)
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