Epigenetic aspects on therapy development for gastroenteropancreatic neuroendocrine tumors

scientific article published on 24 March 2012

Epigenetic aspects on therapy development for gastroenteropancreatic neuroendocrine tumors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1159/000336087
P698PubMed publication ID22456267

P2093author name stringCatharina Larsson
P2860cites workmiR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical CancerQ45119395
A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesisQ46050836
Deregulation of both imprinted and expressed alleles of the insulin–like growth factor 2 gene during β–cell tumorigenesisQ46146329
Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human.Q48096674
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinomaQ48100816
Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.Q52575556
Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system.Q54447289
Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms.Q54738057
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionQ24297027
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locusQ24313196
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shoresQ24649374
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 geneQ28145754
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1Q28243243
Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the geneQ28249576
Positional cloning of the gene for multiple endocrine neoplasia-type 1Q28307577
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4cQ28506197
Hypomethylation distinguishes genes of some human cancers from their normal counterpartsQ29619217
Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinomaQ30320562
Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypesQ33366330
Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cellsQ33998266
Guidelines for diagnosis and therapy of MEN type 1 and type 2.Q34104591
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinomaQ34209973
A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript.Q35288950
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosisQ36324689
Epigenetic therapy of cancer: past, present and futureQ36399557
IGF2: epigenetic regulation and role in development and diseaseQ36561897
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor riskQ36693375
Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspectiveQ37347306
Multiple endocrine neoplasia type 1: a chromatin writer's block.Q37517691
Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signalingQ38442944
Oncogenic role of miR-483-3p at the IGF2/483 locusQ39715206
KRJ-I and BON cell lines: defining an appropriate enterochromaffin cell neuroendocrine tumor model.Q39871460
Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumorsQ40127683
Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors).Q40136348
Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cellsQ40198503
Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.Q40463075
Varying Opinions on the Authenticity of a Human Midgut Carcinoid Cell Line – LetterQ42815034
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenesQ43470250
MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of casesQ44303888
CpG island methylation in carcinoid and pancreatic endocrine tumorsQ44313522
P433issue1
P304page(s)19-25
P577publication date2012-03-24
P1433published inNeuroendocrinologyQ2410309
P1476titleEpigenetic aspects on therapy development for gastroenteropancreatic neuroendocrine tumors
P478volume97

Reverse relations

cites work (P2860)
Q38272919Epigenetic changes in gastroenteropancreatic neuroendocrine tumours
Q47393972Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets
Q38132768Targeting the somatostatin receptor in pituitary and neuroendocrine tumors
Q33709979The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors

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