The roles of microRNAs in sarcomas

scientific article published on 23 May 2012

The roles of microRNAs in sarcomas is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PATH.4037
P698PubMed publication ID22488672

P50authorThomas A HughesQ37383359
P2093author name stringEldo T Verghese
Ruth Drury
P2860cites workPathology of soft-tissue tumors: daily diagnosis, molecular cytogenetics and experimental approachQ37559856
MicroRNA-21: a novel therapeutic target in human cancerQ37817633
MicroRNA regulation by RNA-binding proteins and its implications for cancerQ37913018
A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAsQ38334606
Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcomaQ38338166
S-MED: sarcoma microRNA expression databaseQ38431264
MicroRNA-409 suppresses tumour cell invasion and metastasis by directly targeting radixin in gastric cancersQ39426037
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancyQ39465507
MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migrationQ39526077
MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CMLQ39531134
miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1.Q39604058
Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomasQ39608984
Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcomaQ39669508
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cellsQ39716224
MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancerQ39736530
Functional elucidation of MiR-34 in osteosarcoma cells and primary tumor samplesQ39820788
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cellsQ42009448
Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcomaQ44364850
MicroRNA expression signature of human sarcomasQ47836377
Identification of Differentially Expressed MicroRNAs in OsteosarcomaQ21296759
miRBase: integrating microRNA annotation and deep-sequencing dataQ24615914
Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cellsQ24632284
MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma developmentQ24648202
Non-coding RNAs in human diseaseQ29618039
microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cellsQ33629095
Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumoursQ33758070
RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancerQ33762535
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cellsQ33895297
MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomasQ33906031
Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcomaQ33938849
Let-7a is a direct EWS-FLI-1 target implicated in Ewing's sarcoma developmentQ33997274
A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell-related malignancyQ34033361
miR-126 functions as a tumour suppressor in human gastric cancerQ34125258
Down-regulation of miR-126 expression in colorectal cancer and its clinical significanceQ34129387
miRNA expression profiling of lung adenocarcinomas: correlation with mutational statusQ34136203
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcomaQ34228576
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cellsQ34912570
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expressionQ35086698
Advances in sarcoma genomics and new therapeutic targetsQ35993346
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcomaQ37311506
Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?Q37325228
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)385-391
P577publication date2012-05-23
P1433published inJournal of PathologyQ400296
P1476titleThe roles of microRNAs in sarcomas
P478volume227

Reverse relations

cites work (P2860)
Q39996382A selective screening platform reveals unique global expression patterns of microRNAs in a cohort of human soft-tissue sarcomas
Q38964936Epigenetic and genetic changes in soft tissue sarcomas: a review
Q37235523Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes.
Q40786472Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors
Q99406327MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway
Q27006159MicroRNAs in soft tissue sarcomas: overview of the accumulating evidence and importance as novel biomarkers
Q28085250MicroRNAs in the pathobiology of sarcomas
Q61626102microRNAs in the Malignant Transformation Process

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