The expanding field of SILAC.

scientific article published on 25 April 2012

The expanding field of SILAC. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00216-012-5998-3
P698PubMed publication ID22526667

P2093author name stringShao-En Ong
P2860cites workA proteomics strategy to elucidate functional protein-protein interactions applied to EGF signalingQ24294449
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Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomicsQ28131742
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Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnoverQ38500109
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Large-scale phosphosite quantification in tissues by a spike-in SILAC method.Q39509462
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiationQ39575648
Systems biology "on-the-fly": SILAC-based quantitative proteomics and RNAi approach in Drosophila melanogasterQ39658267
Super-SILAC mix for quantitative proteomics of human tumor tissueQ39719028
Turnover of the human proteome: determination of protein intracellular stability by dynamic SILAC.Q39924707
Absolute SILAC for accurate quantitation of proteins in complex mixtures down to the attomole level.Q40013753
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.Q40242350
The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometryQ42122474
Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilisQ43051533
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycleQ43474246
Quantitative analysis of bacterial and mammalian proteomes using a combination of cysteine affinity tags and 15N-metabolic labelingQ43608877
Trypsin cleaves exclusively C-terminal to arginine and lysine residuesQ44807551
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathwayQ45234630
SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell functionQ46458771
Stable isotope labeling of Arabidopsis thaliana cells and quantitative proteomics by mass spectrometryQ46641130
Quantitative cancer proteomics: stable isotope labeling with amino acids in cell culture (SILAC) as a tool for prostate cancer researchQ47717654
Quantitative mouse brain proteomics using culture-derived isotope tags as internal standardsQ48925714
The turnover kinetics of major histocompatibility complex peptides of human cancer cells.Q53650261
Proteomics strategy for quantitative protein interaction profiling in cell extracts.Q54721073
Quantitative proteomics by amino acid labeling in C. elegansQ57279143
Global quantification of mammalian gene expression controlQ28238103
Identifying and quantifying in vivo methylation sites by heavy methyl SILACQ28241075
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory rolesQ28247080
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomicsQ28277407
Mass spectrometry-based proteomics turns quantitativeQ28291379
Global analysis of cellular protein translation by pulsed SILACQ28302639
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagentsQ29547450
Dynamics of protein turnover, a missing dimension in proteomicsQ30862513
Proteome dynamics in complex organisms: using stable isotopes to monitor individual protein turnover rates.Q31138528
Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns.Q31164900
In vivo residue-specific histone methylation dynamicsQ33661504
Full dynamic range proteome analysis of S. cerevisiae by targeted proteomicsQ33674206
More than 100,000 detectable peptide species elute in single shotgun proteomics runs but the majority is inaccessible to data-dependent LC-MS/MS.Q33817365
Quantitative, high-resolution proteomics for data-driven systems biologyQ33891413
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitorsQ34005966
A Protein Epitope Signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell linesQ34037167
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).Q34093722
A framework for intelligent data acquisition and real-time database searching for shotgun proteomicsQ34101644
Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonistsQ34122067
Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MSQ34192662
The SILAC fly allows for accurate protein quantification in vivo.Q34193643
Kinetics of re-establishing H3K79 methylation marks in global human chromatin.Q34236695
Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4.Q34341785
Proteomics: the move to mixturesQ34465036
Gas-phase purification enables accurate, multiplexed proteome quantification with isobaric taggingQ35488768
MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomicsQ35491186
Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteinsQ35830128
SILAC compatible strain of Pichia pastoris for expression of isotopically labeled protein standards and quantitative proteomicsQ35993587
Decision tree-driven tandem mass spectrometry for shotgun proteomicsQ37002998
Identifying the proteins to which small-molecule probes and drugs bind in cellsQ37114227
A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elementsQ37119633
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discoveryQ37119996
Evaluation of the variation in sample preparation for comparative proteomics using stable isotope labeling by amino acids in cell cultureQ37219849
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)967-976
P577publication date2012-04-25
P1433published inAnalytical and Bioanalytical ChemistryQ2845280
P1476titleThe expanding field of SILAC.
P478volume404

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cites work (P2860)
Q38797022A SILAC-Based Approach Elicits the Proteomic Responses to Vancomycin-Associated Nephrotoxicity in Human Proximal Tubule Epithelial HK-2 Cells.
Q40065746A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells
Q35879468A proteomic approach to obesity and type 2 diabetes
Q38526667Advances in Mass Spectrometric Tools for Probing Neuropeptides
Q39037345Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.
Q36477909Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming.
Q38262764Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer
Q37714278Cd²⁺-induced alteration of the global proteome of human skin fibroblast cells
Q38837694Clinically-oriented proteomic investigation of sickle cell disease: Opportunities and challenges.
Q34634946De Novo proteome analysis of genetically modified tumor cells by a metabolic labeling/azide-alkyne cycloaddition approach
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Q36040261In vivo kinetic approach reveals slow SOD1 turnover in the CNS.
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Q37308204Neutron encoded labeling for peptide identification.
Q28385880Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells
Q28388409Proteomic response to 5,6-dimethylxanthenone 4-acetic acid (DMXAA, vadimezan) in human non-small cell lung cancer A549 cells determined by the stable-isotope labeling by amino acids in cell culture (SILAC) approach
Q26738539Proteomic-Based Approaches for the Study of Cytokines in Lung Cancer
Q37661330Quantification of peptide m/z distributions from 13C-labeled cultures with high-resolution mass spectrometry.
Q38607782Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.
Q39298361Quantitative proteomics in plant protease substrate identification.
Q48169059Quantitative proteomics to study a small molecule targeting the loss of von Hippel-Lindau in renal cell carcinomas
Q38533946Quantitative proteomics using SILAC: Principles, applications, and developments
Q38287734SILAC for biomarker discovery
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Q38268971Super-SILAC: current trends and future perspectives
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Q34564656Target identification of small molecules based on chemical biology approaches
Q34563129Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy
Q38245231Toward a systems-level view of dynamic phosphorylation networks

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