The complex genetic basis of plasma triglycerides

scientific article published on June 2012

The complex genetic basis of plasma triglycerides is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1008492484
P356DOI10.1007/S11883-012-0243-2
P698PubMed publication ID22528520
P5875ResearchGate publication ID224824605

P50authorRobert A. HegeleQ58046422
P2093author name stringChristopher T Johansen
P2860cites workChylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defectsQ24298184
Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipaseQ24323221
Biological, clinical and population relevance of 95 loci for blood lipidsQ24622541
Hypertriglyceridemia: its etiology, effects and treatmentQ24672914
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemiaQ28118749
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studiesQ28281855
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemiaQ28295479
Genetic and developmental regulation of the lipoprotein lipase gene: loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expressionQ28593108
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemiaQ28943439
Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemiaQ33644452
Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism.Q33758277
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairmentQ34048473
Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemiaQ34089350
Childhood-onset chylomicronaemia with reduced plasma lipoprotein lipase activity and mass: identification of a novel GPIHBP1 mutationQ34164025
Genetic determinants of plasma triglyceridesQ34503333
Triglycerides and heart disease: still a hypothesis?Q35120360
The role of triglycerides in atherosclerosisQ35602424
Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemiaQ35784042
New wrinkles in lipoprotein lipase biology.Q36060371
Homozygous missense mutation (G56R) in glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPI-HBP1) in two siblings with fasting chylomicronemia (MIM 144650).Q36087336
An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemiaQ36582772
Common and rare gene variants affecting plasma LDL cholesterolQ36711327
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.Q37036119
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotectionQ37171168
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.Q37389540
Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease riskQ37848012
Genetic bases of hypertriglyceridemic phenotypesQ37868881
Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemiaQ39369438
Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.Q39446839
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in womenQ40192779
The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolismQ41909224
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH.Q43106855
A specific apoprotein activator for lipoprotein lipaseQ44766585
Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 geneQ46715156
Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and WomenQ61162458
Apolipoprotein A5 and hypertriglyceridemiaQ81341210
P433issue3
P921main subjecttriglycerideQ186319
P304page(s)227-234
P577publication date2012-06-01
P1433published inCurrent Atherosclerosis ReportsQ20821076
P1476titleThe complex genetic basis of plasma triglycerides
P478volume14

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cites work (P2860)
Q61804191A Compound Heterozygous Mutation of Lipase Maturation Factor 1 is Responsible for Hypertriglyceridemia of a Patient
Q64121082Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups
Q36197671Binding of human apoA-I[K107del] variant to TG-rich particles: implications for mechanisms underlying hypertriglyceridemia
Q38366873Chylomicronaemia--current diagnosis and future therapies
Q34689708Comprehensive evaluation of the association of APOE genetic variation with plasma lipoprotein traits in U.S. whites and African blacks
Q38141575Demystifying the management of hypertriglyceridaemia.
Q46588659Genetic risk prediction in a small cohort of healthy adults in Atlanta
Q39324048Genetics of Triglycerides and the Risk of Atherosclerosis
Q60533968Hypertriglyceridemia
Q94365453Increased Binding of Apolipoproteins A-I and E4 to Triglyceride-Rich Lipoproteins is linked to Induction of Hypertriglyceridemia
Q38076370Postprandial hypertriglyceridemia and cardiovascular disease: current and future therapies.
Q36744086Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.

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