Recent developments with live-attenuated recombinant paramyxovirus vaccines

scientific article published on 08 May 2012

Recent developments with live-attenuated recombinant paramyxovirus vaccines is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/RMV.1717
P698PubMed publication ID22570186

P50authorManuel Rosa-CalatravaQ56432987
Bruno LinaQ61117468
Guy BoivinQ90829727
P2093author name stringJean-Christophe Le Bayon
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Intranasal immunization with a replication-deficient adenoviral vector expressing the fusion glycoprotein of respiratory syncytial virus elicits protective immunity in BALB/c miceQ45386439
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Soluble recombinant human metapneumovirus G protein is immunogenic but not protectiveQ33950358
Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidatesQ33984333
Recombinant newcastle disease virus expressing a foreign viral antigen is attenuated and highly immunogenic in primatesQ34092801
Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccineQ34206177
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Chimeric recombinant human metapneumoviruses with the nucleoprotein or phosphoprotein open reading frame replaced by that of avian metapneumovirus exhibit improved growth in vitro and attenuation in vivoQ34228628
Combined Live Measles, Mumps, and Rubella Virus VaccinesQ34240333
Addition of N-glycans in the stalk of the Newcastle disease virus HN protein blocks its interaction with the F protein and prevents fusionQ34301817
Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vectorQ34302198
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus diseaseQ34330690
Epidemiology and cost of infection with human parainfluenza virus types 1 and 2 in young childrenQ34333040
Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteinsQ34457791
The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon responseQ34651391
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Progress in understanding and controlling respiratory syncytial virus: still crazy after all these yearsQ35566601
Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton ratsQ35634929
The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcriptionQ35645905
Sendai virus-based RSV vaccine protects African green monkeys from RSV infectionQ35667184
Human metapneumovirus (HMPV) binding and infection are mediated by interactions between the HMPV fusion protein and heparan sulfateQ35826221
Frequent frameshift and point mutations in the SH gene of human metapneumovirus passaged in vitroQ35857720
Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genesQ35924915
Reverse genetics of negative-stranded RNA viruses: a global perspectiveQ36053078
Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3' genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates.Q36088161
Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirusQ36422618
Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and BQ36453608
The structural basis of paramyxovirus invasionQ36469974
A conserved region between the heptad repeats of paramyxovirus fusion proteins is critical for proper F protein foldingQ36851832
Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primatesQ36898701
Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entryQ37051640
Integrin alphavbeta1 promotes infection by human metapneumovirusQ37068968
Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]Q37093418
Risk factors in children hospitalized with RSV bronchiolitis versus non-RSV bronchiolitisQ37144043
Delivery to the lower respiratory tract is required for effective immunization with Newcastle disease virus-vectored vaccines intended for humansQ37297096
Sendai virus recombinant vaccine expressing hPIV-3 HN or F elicits protective immunity and combines with a second recombinant to prevent hPIV-1, hPIV-3 and RSV infectionsQ37308711
Human PIV-2 recombinant Sendai virus (rSeV) elicits durable immunity and combines with two additional rSeVs to protect against hPIV-1, hPIV-2, hPIV-3, and RSV.Q37348134
The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccinesQ37384009
Parainfluenza virus type 3 expressing the native or soluble fusion (F) Protein of Respiratory Syncytial Virus (RSV) confers protection from RSV infection in African green monkeysQ37568127
Respiratory syncytial virus disease: update on treatment and preventionQ37822453
Local cytokine response upon respiratory syncytial virus infection.Q37825057
Ten years of human metapneumovirus research.Q37954833
Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamstersQ39123938
Expression of the surface glycoproteins of human parainfluenza virus type 3 by bovine parainfluenza virus type 3, a novel attenuated virus vaccine vectorQ39593656
AIK-C measles vaccine expressing fusion protein of respiratory syncytial virus induces protective antibodies in cotton ratsQ39615678
Cleavage at the furin consensus sequence RAR/KR(109) and presence of the intervening peptide of the respiratory syncytial virus fusion protein are dispensable for virus replication in cell cultureQ39684652
Induction of apoptosis by paramyxovirus simian virus 5 lacking a small hydrophobic geneQ39732519
Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3Q39796610
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signallingQ39960512
Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicityQ39997643
Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virusQ40048609
Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tractQ40158643
Function of small hydrophobic proteins of paramyxovirusQ40324541
Introducing point and deletion mutations into the P/C gene of human parainfluenza virus type 1 (HPIV1) by reverse genetics generates attenuated and efficacious vaccine candidatesQ40338559
Live-attenuated intranasal parainfluenza virus type 2 vaccine candidates developed by reverse genetics containing L polymerase protein mutations imported from heterologous paramyxovirusesQ40407821
Effectiveness of maternal influenza immunization in mothers and infantsQ40409398
Safety and immunogenicity of intranasal murine parainfluenza virus type 1 (Sendai virus) in healthy human adultsQ40490986
A bovine parainfluenza virus type 3 vaccine is safe and immunogenic in early infancyQ40513717
Phase 2 evaluation of parainfluenza type 3 cold passage mutant 45 live attenuated vaccine in healthy children 6-18 months old.Q40541369
Immunopathogenesis of vaccine-enhanced RSV disease.Q40595357
Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancyQ40614352
Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitroQ40630466
Contribution of the respiratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivoQ40771213
An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccineQ40940832
The paramyxovirus SV5 small hydrophobic (SH) protein is not essential for virus growth in tissue culture cellsQ41003033
Identification of regions on the fusion protein of human parainfluenza virus type 2 which are required for haemagglutinin-neuraminidase proteins to promote cell fusionQ41064314
Comparison of soluble and secreted forms of human parainfluenza virus type 3 glycoproteins expressed from mammalian and insect cells as subunit vaccinesQ42070355
Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenonQ42148034
Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.Q42428474
Virologically confirmed population-based burden of hospitalization caused by respiratory syncytial virus, adenovirus, and parainfluenza viruses in children in Hong Kong.Q43173863
Differential production of inflammatory cytokines in primary infection with human metapneumovirus and with other common respiratory viruses of infancyQ44286818
A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeysQ44776054
Parainfluenza virus type 3: seasonality and risk of infection and reinfection in young childrenQ44825036
Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaquesQ45216908
Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infectionQ45220298
Respiratory syncytial virus-associated hospitalizations among infants and young children in the United States, 1997-2006.Q45232426
Phase 1 study of the safety and immunogenicity of a live, attenuated respiratory syncytial virus and parainfluenza virus type 3 vaccine in seronegative childrenQ45363218
A randomized controlled trial of motavizumab versus palivizumab for the prophylaxis of serious respiratory syncytial virus disease in children with hemodynamically significant congenital heart diseaseQ45367066
Phase-I study MEDI-534, of a live, attenuated intranasal vaccine against respiratory syncytial virus and parainfluenza-3 virus in seropositive childrenQ45384017
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectattenuated vaccineQ1810913
P304page(s)15-34
P577publication date2012-05-08
P1433published inReviews in Medical VirologyQ15766137
P1476titleRecent developments with live-attenuated recombinant paramyxovirus vaccines
P478volume23

Reverse relations

cites work (P2860)
Q39142106Characterization of a key residue for hyperfusogenic phenotype in human parainfluenza virus type 2 (hPIV-2) fusion glycoprotein.
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Q38266413RNA-based viral vectors
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