Non-glucose metabolism in cancer cells--is it all in the fat?

scientific article published on December 2012

Non-glucose metabolism in cancer cells--is it all in the fat? is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1028362175
P356DOI10.1007/S10555-012-9384-6
P8608Fatcat IDrelease_gdljqtok55gupj22kthy2mp5ii
P698PubMed publication ID22706846

P2093author name stringSwethajit Biswas
John Lunec
Kim Bartlett
P2860cites workInhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPKQ21142775
Hallmarks of Cancer: The Next GenerationQ22252312
Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell linesQ24314970
Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genomeQ24338784
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cellsQ24561962
Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group studyQ27851561
TOR signaling in growth and metabolismQ27860757
On the Origin of Cancer CellsQ27861025
Superoxide activates mitochondrial uncoupling proteinsQ28214829
Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic isletsQ28244291
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancerQ28253300
Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinomaQ28281551
Mitochondrial tumour suppressors: a genetic and biochemical updateQ28285094
Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesisQ28472927
Genomic and mutational analysis of the mitochondrial trifunctional protein beta-subunit (HADHB) gene in patients with trifunctional protein deficiencyQ28645929
Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissuesQ28646513
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolismQ29617213
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesisQ29617613
Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancerQ30430510
Cloning and functional characterization of ACAD-9, a novel member of human acyl-CoA dehydrogenase familyQ31113056
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescenceQ33283342
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.Q33734395
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesisQ33914549
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolismQ33965102
Fatty acid oxidation disordersQ34112648
Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic systemQ34262892
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapyQ34296575
ATP citrate lyase inhibition can suppress tumor cell growthQ34651116
Biochemical and physiological function of stearoyl-CoA desaturaseQ34898764
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesisQ35207795
Mitochondrial beta-oxidationQ35631612
Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscleQ36274041
The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cellsQ36661071
The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activationQ36925362
Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolismQ37293677
Hypoxia-inducible factor 2 regulates hepatic lipid metabolismQ37302297
The Randle cycle revisited: a new head for an old hat.Q37337283
De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapyQ37437194
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicityQ37480801
The Akt-SREBP nexus: cell signaling meets lipid metabolism.Q37684518
IDH mutations in glioma and acute myeloid leukemiaQ37778541
Cancer-associated IDH mutations: biomarker and therapeutic opportunitiesQ37802750
Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitorsQ39878963
Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytesQ39906678
Gene silencing for epidermal growth factor receptor variant III induces cell-specific cytotoxicityQ39918802
A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproductionQ40012089
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.Q40012178
Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growthQ40222158
Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cellsQ40430794
In support of fatty acid synthase (FAS) as a metabolic oncogene: extracellular acidosis acts in an epigenetic fashion activating FAS gene expression in cancer cellsQ40496369
Genes for the human mitochondrial trifunctional protein alpha- and beta-subunits are divergently transcribed from a common promoter regionQ40967453
Mammalian mitochondrial beta-oxidationQ41280085
All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.Q43081541
Molecular evolution of the metazoan PHD-HIF oxygen-sensing systemQ44193945
CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailabilityQ45152482
tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1.Q46450562
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stromaQ46902015
The fatty acid synthase gene is a conserved p53 family target from worm to human.Q47069045
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cellsQ49145391
UCP3 protein regulation in human skeletal muscle fibre types I, IIa and IIx is dependent on exercise intensity.Q54768942
Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma☆Q58426214
P433issue3-4
P921main subjectglycobiologyQ899224
P304page(s)689-698
P577publication date2012-12-01
P1433published inCancer and Metastasis ReviewsQ2647982
P1476titleNon-glucose metabolism in cancer cells--is it all in the fat?
P478volume31