ArtinM offers new perspectives in the development of antifungal therapy

scientific article published on 15 June 2012

ArtinM offers new perspectives in the development of antifungal therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMICB.2012.00218
P932PMC publication ID3375580
P698PubMed publication ID22715337
P5875ResearchGate publication ID227401465

P50authorLuciana Pereira RuasQ59287208
P2093author name stringMaria-Cristina Roque-Barreira
Fernanda C Carvalho
P2860cites workCloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cellsQ24338229
MD-2 Is Necessary for the Toll-Like Receptor 4 Protein To Undergo Glycosylation Essential for Its Translocation to the Cell SurfaceQ24675313
Innate immune recognitionQ27860721
T helper 1-inducing adjuvant protects against experimental paracoccidioidomycosisQ28472266
N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharideQ28646124
cDNA cloning and functional expression of KM+, the mannose-binding lectin from Artocarpus integrifolia seedsQ33225765
Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunityQ33410830
Therapeutic DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosisQ34184716
The pathobiology of Paracoccidioides brasiliensisQ34517633
Toll-like receptors as key mediators in innate antifungal immunityQ34554648
Immunity to fungal infectionsQ35602207
Interferon-gamma and tumor necrosis factor-alpha determine resistance to Paracoccidioides brasiliensis infection in miceQ35810117
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytesQ36356764
Recognition and signaling by toll-like receptors.Q36527707
Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99Q37462710
T cell immunity and vaccines against invasive fungal diseasesQ37911513
Nitric oxide participation in the fungicidal mechanism of gamma interferon-activated murine macrophages against Paracoccidioides brasiliensis conidiaQ39515477
Protective role of gamma interferon in experimental pulmonary paracoccidioidomycosisQ39570086
Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2.Q40259278
Impairment of host defense against disseminated candidiasis in mice overexpressing GATA-3Q40332012
Intracellular multiplication of Paracoccidioides brasiliensis in macrophages: killing and restriction of multiplication by activated macrophagesQ40427628
Four N-linked glycosylation sites in human toll-like receptor 2 cooperate to direct efficient biosynthesis and secretion.Q40549942
Therapeutic administration of KM+ lectin protects mice against Paracoccidioides brasiliensis infection via interleukin-12 production in a toll-like receptor 2-dependent mechanismQ40645368
KM(+), a lectin from Artocarpus integrifolia, induces IL-12 p40 production by macrophages and switches from type 2 to type 1 cell-mediated immunity against Leishmania major antigens, resulting in BALB/c mice resistance to infectionQ40755708
MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptorQ40768976
Toll-like receptor 4 signaling leads to severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells.Q42141300
Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: comparison with infected and non-infected controlsQ42518235
MyD88 signaling is required for efficient innate and adaptive immune responses to Paracoccidioides brasiliensis infectionQ42779098
Real-time monitoring and kinetic parameter estimation of the affinity interaction of jArtinM and rArtinM with peroxidase glycoprotein by the electrogravimetric technique.Q42982649
Resistance to Paracoccidioides brasiliensis infection is linked to a preferential Th1 immune response, whereas susceptibility is associated with absence of IFN-gamma productionQ44226306
DNAhsp65 vaccination induces protection in mice against Paracoccidioides brasiliensis infection.Q44713068
Lectin KM+-induced neutrophil haptotaxis involves binding to lamininQ45225284
Neutrophil activation induced by ArtinM: release of inflammatory mediators and enhancement of effector functions.Q46018567
Artin M: a rational substitution for the names artocarpin and KM+.Q46500500
Killing of Paracoccidioides brasiliensis yeast cells by IFN-gamma and TNF-alpha activated murine peritoneal macrophages: evidence of H(2)O (2) and NO effector mechanisms.Q46581736
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformansQ46970232
Cytokines produced by susceptible and resistant mice in the course of Paracoccidioides brasiliensis infectionQ47708217
Production of pro- and anti-inflammatory cytokines by monocytes from patients with paracoccidioidomycosisQ47925484
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cellsQ47991722
Protection againstParacoccidioides brasiliensisinfection conferred by the prophylactic administration of native and recombinant ArtinMQ58887780
Mast Cell Degranulation Induced by Lectins: Effect on Neutrophil RecruitmentQ59651713
Immunosuppression in paracoccidioidomycosis: T cell hyporesponsiveness to two Paracoccidioides brasiliensis glycoproteins that elicit strong humoral immune responseQ73292684
Imbalance of IL-2, IFN-gamma and IL-10 secretion in the immunosuppression associated with human paracoccidioidomycosisQ73584683
Production of IFN-gamma is impaired in patients with paracoccidioidomycosis during active disease and is restored after clinical remissionQ73991745
Production of pro-inflammatory cytokines during the early stages of experimental Paracoccidioides brasiliensis infectionQ79341221
[Guidelines in paracoccidioidomycosis]Q80102713
A centennial: discovery of Paracoccidioides brasiliensisQ81940271
HSP65 DNA as therapeutic strategy to treat experimental paracoccidioidomycosisQ82381855
Artin M enhances TNF-α production and phagocytosis of Candida albicans mediated by dectin-1 and mannose receptorsQ83153532
Interleukin-10 but not Transforming Growth Factor beta inhibits murine activated macrophages Paracoccidioides brasiliensis killing: effect on H2O2 and NO productionQ84107276
TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary model of fungal infectionQ84122762
Protective effect of Artin M from extract of Artocarpus integrifolia seeds by Th1 and Th17 immune response on the course of infection by Candida albicansQ84188724
P407language of work or nameEnglishQ1860
P304page(s)218
P577publication date2012-06-15
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleArtinM offers new perspectives in the development of antifungal therapy
P478volume3

Reverse relations

cites work (P2860)
Q38264288Adjuvants and delivery systems for antifungal vaccines: current state and future developments
Q54205003Effect of ArtinM on Human Blood Cells During Infection With Paracoccidioides brasiliensis.
Q38054150Important aspects of oral paracoccidioidomycosis--a literature review
Q38072603The immunomodulatory effect of plant lectins: a review with emphasis on ArtinM properties
Q34633989Therapeutic administration of recombinant Paracoccin confers protection against paracoccidioides brasiliensis infection: involvement of TLRs.
Q42002277Vaccines and immunotherapy against fungi: the new frontier