| scholarly article | Q13442814 |
| P2093 | author name string | Elizabeth A Martin | |
| Ruth Roberts | |||
| Damian G Deavall | |||
| Judith M Horner | |||
| P2860 | cites work | Cardioprotective interventions for cancer patients receiving anthracyclines | Q24243021 |
| Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways | Q24309037 | ||
| Reactive oxygen species: role in the development of cancer and various chronic conditions | Q24548312 | ||
| The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic | Q24655011 | ||
| Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance | Q24813418 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| Oxidative DNA damage: mechanisms, mutation, and disease | Q28182969 | ||
| Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels | Q28203124 | ||
| Identification of a conserved oxidation-sensitive cysteine residue in the NFI family of DNA-binding proteins | Q28241014 | ||
| Mitochondrial myopathy caused by long-term zidovudine therapy | Q28334501 | ||
| Protein oxidative damage | Q74042771 | ||
| Involvement of H2O2 production in cisplatin-induced nephrotoxicity | Q74106583 | ||
| Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria | Q79538091 | ||
| Renal proximal tubule segment-specific nephrotoxicity: an overview on biomarkers and histopathology | Q79966933 | ||
| Savior and slayer: the two faces of p53 | Q81584503 | ||
| High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics. | Q45099684 | ||
| Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors | Q45275872 | ||
| Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy. | Q46034270 | ||
| The cochlear targets of cisplatin: an electrophysiological and morphological time-sequence study | Q46215201 | ||
| Investigation of the adducts formed by reaction of malondialdehyde with adenosine | Q46359330 | ||
| Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. | Q46368551 | ||
| Mechanism of cisplatin ototoxicity: antioxidant system. | Q50519742 | ||
| Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio. | Q51706854 | ||
| Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. | Q52457566 | ||
| Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. | Q52462539 | ||
| Evidence of a specific complex between adriamycin and negatively-charged phospholipids. | Q52764074 | ||
| Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. | Q53478361 | ||
| Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation | Q57267080 | ||
| LIPID PEROXIDATION AND PARKINSON'S DISEASE | Q57943458 | ||
| Cisplatin generates superoxide anion by interaction with DNA in a cell-free system | Q72207060 | ||
| Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro. | Q40398133 | ||
| Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells | Q40643885 | ||
| Cardiac toxicity 4 to 20 years after completing anthracycline therapy | Q41142694 | ||
| A semiquantitative analysis of the effects of cisplatin on the rat stria vascularis | Q42464258 | ||
| Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum | Q42585392 | ||
| The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway | Q42722343 | ||
| Propofol ameliorates doxorubicin-induced oxidative stress and cellular apoptosis in rat cardiomyocytes. | Q42725819 | ||
| Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical | Q42752836 | ||
| Reactive oxygen species assay-based risk assessment of drug-induced phototoxicity: classification criteria and application to drug candidates | Q42813612 | ||
| Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity | Q43297511 | ||
| Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells | Q43525505 | ||
| Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death | Q43664487 | ||
| Increase of enzyme activities following the in vitro peroxidation of normal human red blood cells | Q43665436 | ||
| Ascorbate-induced oxidation of glyceraldehyde-3-phosphate dehydrogenase | Q44546799 | ||
| Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents | Q45040858 | ||
| Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine | Q28366936 | ||
| Protective effects of carvedilol against doxorubicin-induced cardiomyopathy in rats | Q28373377 | ||
| The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival | Q28396081 | ||
| Cellular survival: a play in three Akts | Q29547806 | ||
| Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG | Q29616532 | ||
| Role of oxidative modifications in atherosclerosis | Q29617974 | ||
| Protein oxidation in aging, disease, and oxidative stress | Q29619442 | ||
| Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer | Q30486848 | ||
| Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer. EORTC Head and Neck Cooperative Group | Q33178760 | ||
| Creating context for the use of DNA adduct data in cancer risk assessment: II. Overview of methods of identification and quantitation of DNA damage. | Q33501834 | ||
| Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2). | Q33523365 | ||
| A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin | Q33540751 | ||
| Cardiomyocyte death in doxorubicin-induced cardiotoxicity | Q33604134 | ||
| Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine | Q33632356 | ||
| Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide. | Q33747406 | ||
| Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice | Q33851826 | ||
| Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. | Q33962101 | ||
| Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection? | Q34102834 | ||
| The cardioprotective effect of the iron chelator dexrazoxane (ICRF-187) on anthracycline-mediated cardiotoxicity. | Q34120033 | ||
| Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management | Q34129236 | ||
| Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway | Q34278037 | ||
| Lipid peroxidation in diabetes mellitus | Q34384380 | ||
| Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding | Q34397394 | ||
| The stalling of transcription at abasic sites is highly mutagenic | Q34463060 | ||
| Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein | Q34625381 | ||
| Biological consequences of free radical-damaged DNA bases. | Q34710048 | ||
| JNK signaling in apoptosis | Q34713366 | ||
| Lipid peroxidation in aging brain and Alzheimer's disease | Q34809194 | ||
| Trastuzumab-induced cardiac dysfunction: A 'dual-hit' | Q35532125 | ||
| Pharmacogenomics of cisplatin-induced ototoxicity | Q35553827 | ||
| Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity | Q35566803 | ||
| Substrate specificities and excision kinetics of DNA glycosylases involved in base-excision repair of oxidative DNA damage | Q35592862 | ||
| Free radical-mediated oxidation of free amino acids and amino acid residues in proteins | Q35602220 | ||
| Impact of long-term serum platinum concentrations on neuro- and ototoxicity in Cisplatin-treated survivors of testicular cancer | Q35721076 | ||
| Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis | Q35749434 | ||
| Oxidative DNA damage and disease: induction, repair and significance | Q35876708 | ||
| BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure | Q35886872 | ||
| Dexrazoxane : a review of its use for cardioprotection during anthracycline chemotherapy | Q36126521 | ||
| Free radicals and antioxidants in human health: current status and future prospects. | Q36135155 | ||
| Base-excision repair of oxidative DNA damage by DNA glycosylases | Q36212606 | ||
| Biomarkers of oxidative damage in human disease. | Q36399178 | ||
| Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products | Q36445449 | ||
| Future opportunities in preventing cisplatin induced ototoxicity | Q36509479 | ||
| Protein oxidation and cellular homeostasis: Emphasis on metabolism. | Q36615395 | ||
| Mechanisms of cell death in oxidative stress | Q36658125 | ||
| Mitochondrial and nuclear p53 localization in cardiomyocytes: redox modulation by doxorubicin (Adriamycin)? | Q36824985 | ||
| Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins | Q36843138 | ||
| Influence of the local helical conformation on the guanine modifications generated from one-electron DNA oxidation | Q36865494 | ||
| An introduction to the metabolic determinants of anthracycline cardiotoxicity. | Q36891719 | ||
| Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis | Q36891734 | ||
| Mechanism of oxidative DNA damage repair and relevance to human pathology | Q37033569 | ||
| Base excision repair of oxidative DNA damage and association with cancer and aging | Q37090426 | ||
| A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide | Q37229749 | ||
| Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction | Q37270571 | ||
| Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity | Q37318389 | ||
| Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity | Q37353430 | ||
| Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron | Q37421187 | ||
| Cardiac toxicity with anti-HER-2 therapies: what have we learned so far? | Q37471532 | ||
| Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy | Q37624003 | ||
| Liver injury caused by drugs: an update | Q37798493 | ||
| Role of oxidative stress and DNA damage in human carcinogenesis | Q37826939 | ||
| Molecular targets of oxidative stress. | Q37839122 | ||
| Akt signalling in health and disease. | Q37881228 | ||
| Drug-induced cardiac mitochondrial toxicity and protection: from doxorubicin to carvedilol. | Q37896107 | ||
| Regulation of protein tyrosine phosphatases by reversible oxidation | Q37920470 | ||
| Pharmacogenetics of genes across the doxorubicin pathway. | Q37932556 | ||
| Heart to heart with trastuzumab: a review on cardiac toxicity. | Q37962451 | ||
| Steady-state and pre-steady-state kinetic analysis of 8-oxo-7,8-dihydroguanosine triphosphate incorporation and extension by replicative and repair DNA polymerases | Q38333086 | ||
| Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity. | Q38487545 | ||
| Cisplatin nephrotoxicity. A review | Q38730217 | ||
| Nuclear transport: a switch for the oxidative stress-signaling circuit? | Q38733049 | ||
| Pro-oxidant properties of AZT and other thymidine analogues in macrophages: implication of the azido moiety in oxidative stress | Q39753791 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 645460 | |
| P577 | publication date | 2012-08-05 | |
| P1433 | published in | Journal of toxicology | Q26853888 |
| P1476 | title | Drug-induced oxidative stress and toxicity | |
| P478 | volume | 2012 |
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| Q35045461 | Fucoxanthin Protects Cultured Human Keratinocytes against Oxidative Stress by Blocking Free Radicals and Inhibiting Apoptosis |
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